IN188411B - - Google Patents

Info

Publication number
IN188411B
IN188411B IN724DE1998A IN188411B IN 188411 B IN188411 B IN 188411B IN 724DE1998 A IN724DE1998 A IN 724DE1998A IN 188411 B IN188411 B IN 188411B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Wook Lee-Korea Jong
Young Lee-Korea Bong
Seop Kim-Korea Chang
Kyu Lee-Korea Seung
Seog Song-Korea Keun
Jin Lee-Korea Song
Jeon Shim-Korea Woo
Soon Hwang-Korea Man
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of IN188411B publication Critical patent/IN188411B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IN724DE1998 1997-03-27 1998-03-23 IN188411B (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19970010862 1997-03-27
KR19970010863 1997-03-27

Publications (1)

Publication Number Publication Date
IN188411B true IN188411B (fr) 2002-09-21

Family

ID=26632616

Family Applications (1)

Application Number Title Priority Date Filing Date
IN724DE1998 IN188411B (fr) 1997-03-27 1998-03-23

Country Status (22)

Country Link
US (1) US6352993B1 (fr)
EP (1) EP1015444B1 (fr)
JP (1) JP3176379B2 (fr)
KR (1) KR100278857B1 (fr)
CN (1) CN1118464C (fr)
AR (1) AR012181A1 (fr)
AT (1) ATE241613T1 (fr)
AU (1) AU720385B2 (fr)
BR (1) BR9808070A (fr)
CA (1) CA2284795C (fr)
DE (1) DE69815126T2 (fr)
DK (1) DK1015444T3 (fr)
ES (1) ES2200324T3 (fr)
HK (1) HK1026418A1 (fr)
HU (1) HUP0000851A3 (fr)
IN (1) IN188411B (fr)
PT (1) PT1015444E (fr)
RU (1) RU2203894C2 (fr)
TR (1) TR199902383T2 (fr)
TW (1) TW542831B (fr)
UY (1) UY24938A1 (fr)
WO (1) WO1998043968A1 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
AR038368A1 (es) 2002-02-01 2005-01-12 Novartis Ag Compuestos n-pirimidin-2-il-aminas sustituidas como inhibidores de ige, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de un medicamento
EP1534278A4 (fr) 2002-08-01 2006-09-06 Nitromed Inc Inhibiteurs nitroses de la pompe a protons, compositions et procedes d'utilisation
WO2005009980A1 (fr) * 2003-07-22 2005-02-03 Neurogen Corporation Analogues de pyridin-2-ylamine substitues
CA2541989C (fr) * 2003-10-24 2013-10-01 Exelixis, Inc. Modulateurs des p70s6 kinases et procede d'utilisation
EP1682133A1 (fr) 2003-11-03 2006-07-26 AstraZeneca AB Derives d'imidazo 1,2-a pydirine pour le traitement du reflux gastro-oesophagien sans douleur
KR101122376B1 (ko) * 2005-03-09 2012-03-26 주식회사유한양행 신규의 5,6-다이메틸피리미딘 유도체 및 그의 제조방법
WO2007042571A1 (fr) * 2005-10-14 2007-04-19 Neurosearch A/S Nouveaux derives de pyrimidine-2,4-diamine et leur utilisation comme modulateurs de canaux a potassium actives par calcium a conductance faible
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
EP2308877B1 (fr) 2008-08-05 2014-01-22 Daiichi Sankyo Company, Limited Dérivés d'imidazopyridin-2-one
GB0908394D0 (en) 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
GB0913636D0 (en) 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
WO2012065963A2 (fr) 2010-11-15 2012-05-24 Katholieke Universiteit Leuven Nouveaux composés antiviraux
US9850227B2 (en) 2011-02-25 2017-12-26 Yuhan Corporation Diaminopyrimidine derivatives and processes for the preparation thereof
RU2014137448A (ru) * 2012-02-17 2016-04-10 Эббви Инк. Диаминопиримидины, пригодные в качестве ингибиторов респираторно-синцитиального вируса человека (rsv)
WO2013181136A1 (fr) 2012-05-29 2013-12-05 Momentive Performance Materials Gmbh Préparation d'isocyanatosilanes
PE20151413A1 (es) 2012-11-21 2015-10-23 Ptc Therapeutics Inc Inhibidores de bmi-1 de pirimidina inversa sustituida
MX2015011898A (es) 2013-03-13 2016-05-05 Genentech Inc Compuestos de pirazolo y usos de los mismos.
JP6524094B2 (ja) 2013-08-30 2019-06-05 ピーティーシー セラピューティクス, インコーポレイテッド 置換ピリミジンBmi−1阻害剤
JP6507157B2 (ja) * 2013-10-07 2019-04-24 カドモン コーポレイション,リミティド ライアビリティ カンパニー Rhoキナーゼ阻害剤
US10584115B2 (en) 2013-11-21 2020-03-10 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine BMI-1 inhibitors
WO2016064970A1 (fr) * 2014-10-22 2016-04-28 The Board Of Regents Of The University Of Texas System Inhibiteurs à petites molécules ciblant le récepteur du domaine discoïdine 1 et ses utilisations
CN105669642B (zh) * 2014-11-19 2020-06-09 江苏天士力帝益药业有限公司 一种盐酸洛氟普啶的制备方法
AU2017205670B2 (en) * 2016-01-04 2021-05-20 Merck Serono S.A. L-valinate of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof
CN110461833A (zh) * 2017-04-05 2019-11-15 拜耳作物科学股份公司 2-氨基-5-氧基烷基嘧啶衍生物及其用于防治不希望的植物生长的用途
CN114685369B (zh) * 2022-05-17 2024-02-02 河南省科学院高新技术研究中心 一种利用离子液体制备1-甲基-1,2,3,4-四氢异喹啉的方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1182584A (en) 1966-03-31 1970-02-25 Ici Ltd Pyrimidine derivates and the use thereof as fungicides
US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
US3980781A (en) 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
GB1383409A (en) 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US4044136A (en) 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
US3956495A (en) 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4755218A (en) 1985-12-31 1988-07-05 Monsanto Company Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
IL88507A (en) * 1987-12-03 1993-02-21 Smithkline Beckman Intercredit 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them
US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
DE3901448A1 (de) 1989-01-19 1990-07-26 Basf Ag Emulsionscopolymerisate
ES2081863T3 (es) 1989-03-22 1996-03-16 Ciba Geigy Ag Plaguicidas.
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
CA2015981A1 (fr) * 1989-05-10 1990-11-10 Thomas H. Brown Composes
GB9012592D0 (en) 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
CA2095213A1 (fr) 1990-11-06 1992-05-07 Jotham W. Coe Derives de la quinazoline pour intensifier l'activite antitumorale
CZ390992A3 (en) * 1991-04-17 1994-03-16 Pfizer Pyrimidine derivatives, process of their preparation and use as substances for increase of anti-tumor activity
US5276186A (en) 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
KR0144833B1 (ko) 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
DK0640599T3 (da) 1993-08-26 1998-09-28 Ono Pharmaceutical Co 4-Aminopyrimidin-derivater
WO1995010506A1 (fr) 1993-10-12 1995-04-20 The Du Pont Merck Pharmaceutical Company 1n-alkyle-n-arylpyrimidinamines et leurs derives
CA2197298C (fr) 1994-08-13 1999-10-19 Jong Wook Lee Nouveaux derives de la pyrimidine; methodes de preparation
DE69706981T2 (de) * 1996-05-04 2002-06-06 Yuhan Corp Verfahren zur herstellung von pyrimidin-derivaten

Also Published As

Publication number Publication date
DE69815126D1 (de) 2003-07-03
BR9808070A (pt) 2000-03-08
ATE241613T1 (de) 2003-06-15
ES2200324T3 (es) 2004-03-01
PT1015444E (pt) 2003-10-31
HUP0000851A3 (en) 2002-04-29
HUP0000851A1 (hu) 2001-04-28
JP3176379B2 (ja) 2001-06-18
JP2000513014A (ja) 2000-10-03
AR012181A1 (es) 2000-09-27
DK1015444T3 (da) 2003-08-18
DE69815126T2 (de) 2004-04-08
AU6523998A (en) 1998-10-22
HK1026418A1 (en) 2000-12-15
AU720385B2 (en) 2000-06-01
EP1015444B1 (fr) 2003-05-28
UY24938A1 (es) 2001-01-31
TW542831B (en) 2003-07-21
EP1015444A1 (fr) 2000-07-05
KR19980080789A (ko) 1998-11-25
CA2284795C (fr) 2004-01-20
CN1251586A (zh) 2000-04-26
CN1118464C (zh) 2003-08-20
WO1998043968A1 (fr) 1998-10-08
US6352993B1 (en) 2002-03-05
TR199902383T2 (xx) 2000-06-21
KR100278857B1 (ko) 2001-01-15
RU2203894C2 (ru) 2003-05-10
CA2284795A1 (fr) 1998-10-08

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