IN188411B - - Google Patents

Info

Publication number
IN188411B
IN188411B IN724DE1998A IN188411B IN 188411 B IN188411 B IN 188411B IN 724DE1998 A IN724DE1998 A IN 724DE1998A IN 188411 B IN188411 B IN 188411B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Wook Lee-Korea Jong
Young Lee-Korea Bong
Seop Kim-Korea Chang
Kyu Lee-Korea Seung
Seog Song-Korea Keun
Jin Lee-Korea Song
Jeon Shim-Korea Woo
Soon Hwang-Korea Man
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of IN188411B publication Critical patent/IN188411B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IN724DE1998 1997-03-27 1998-03-23 IN188411B (cg-RX-API-DMAC7.html)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19970010862 1997-03-27
KR19970010863 1997-03-27

Publications (1)

Publication Number Publication Date
IN188411B true IN188411B (cg-RX-API-DMAC7.html) 2002-09-21

Family

ID=26632616

Family Applications (1)

Application Number Title Priority Date Filing Date
IN724DE1998 IN188411B (cg-RX-API-DMAC7.html) 1997-03-27 1998-03-23

Country Status (21)

Country Link
US (1) US6352993B1 (cg-RX-API-DMAC7.html)
EP (1) EP1015444B1 (cg-RX-API-DMAC7.html)
JP (1) JP3176379B2 (cg-RX-API-DMAC7.html)
KR (1) KR100278857B1 (cg-RX-API-DMAC7.html)
CN (1) CN1118464C (cg-RX-API-DMAC7.html)
AR (1) AR012181A1 (cg-RX-API-DMAC7.html)
AT (1) ATE241613T1 (cg-RX-API-DMAC7.html)
AU (1) AU720385B2 (cg-RX-API-DMAC7.html)
BR (1) BR9808070A (cg-RX-API-DMAC7.html)
CA (1) CA2284795C (cg-RX-API-DMAC7.html)
DE (1) DE69815126T2 (cg-RX-API-DMAC7.html)
DK (1) DK1015444T3 (cg-RX-API-DMAC7.html)
ES (1) ES2200324T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0000851A3 (cg-RX-API-DMAC7.html)
IN (1) IN188411B (cg-RX-API-DMAC7.html)
PT (1) PT1015444E (cg-RX-API-DMAC7.html)
RU (1) RU2203894C2 (cg-RX-API-DMAC7.html)
TR (1) TR199902383T2 (cg-RX-API-DMAC7.html)
TW (1) TW542831B (cg-RX-API-DMAC7.html)
UY (1) UY24938A1 (cg-RX-API-DMAC7.html)
WO (1) WO1998043968A1 (cg-RX-API-DMAC7.html)

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KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
AR038368A1 (es) 2002-02-01 2005-01-12 Novartis Ag Compuestos n-pirimidin-2-il-aminas sustituidas como inhibidores de ige, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de un medicamento
CA2493618A1 (en) 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
CN1826328A (zh) * 2003-07-22 2006-08-30 神经能质公司 经取代的吡啶－2－基胺类似物
JP4800216B2 (ja) * 2003-10-24 2011-10-26 エグゼリクシス， インコーポレイテッド ｐ７０Ｓ６キナーゼモジュレーターおよび使用方法
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
KR101122376B1 (ko) * 2005-03-09 2012-03-26 주식회사유한양행 신규의 5,6-다이메틸피리미딘 유도체 및 그의 제조방법
WO2007042571A1 (en) * 2005-10-14 2007-04-19 Neurosearch A/S Novel pyrimidine-2,4-diamine derivatives and their use as modulators of small-conductance calcium-activated potassium channels
JP4946482B2 (ja) 2007-02-08 2012-06-06 船井電機株式会社 緩衝用梱包材及びｔｖ受像機の緩衝用梱包材
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
WO2010016490A1 (ja) 2008-08-05 2010-02-11 第一三共株式会社 イミダゾピリジン－２－オン誘導体
GB0908394D0 (en) 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
GB0913636D0 (en) 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
MX2013005478A (es) 2010-11-15 2013-08-29 Univ Leuven Kath Compuestos heterociclicos condensados antivirales.
PL2678331T3 (pl) 2011-02-25 2016-12-30 Pochodne diaminopirymidyny i sposoby ich wytwarzania
JP6141334B2 (ja) * 2012-02-17 2017-06-07 アッヴィ・インコーポレイテッド ヒト呼吸器多核体ウイルス（ｒｓｖ）の阻害剤として有用なジアミノピリミジン
CN104334565A (zh) 2012-05-29 2015-02-04 莫门蒂夫性能材料有限责任公司 异氰酸基硅烷的制备
SG11201503982XA (en) 2012-11-21 2015-06-29 Ptc Therapeutics Inc Substituted reverse pyrimidine bmi-1 inhibitors
CN105980386B (zh) 2013-03-13 2021-08-13 基因泰克公司 吡唑并化合物及其用途
WO2015030847A1 (en) * 2013-08-30 2015-03-05 Ptc Therapeutics, Inc. Substituted pyrimidine bmi-1 inhibitors
JP6507157B2 (ja) * 2013-10-07 2019-04-24 カドモン コーポレイション，リミティド ライアビリティ カンパニー Ｒｈｏキナーゼ阻害剤
US10584115B2 (en) 2013-11-21 2020-03-10 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine BMI-1 inhibitors
CN107206004A (zh) * 2014-10-22 2017-09-26 德克萨斯大学系统董事会 靶向盘状结构域受体1的小分子抑制剂及其用途
CN105669642B (zh) * 2014-11-19 2020-06-09 江苏天士力帝益药业有限公司 一种盐酸洛氟普啶的制备方法
CA3009576A1 (en) * 2016-01-04 2017-07-13 Merck Serono S.A. L-valinate of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof
WO2018184978A1 (de) * 2017-04-05 2018-10-11 Bayer Cropscience Aktiengesellschaft 2-amino-5-oxyalkyl-pyrimidinderivate und deren verwendung zur bekämpfung unerwünschten pflanzenwachstums
BR112021002630A2 (pt) 2018-08-17 2021-05-11 Ptc Therapeutics, Inc. método para tratar câncer pancreático
CN114685369B (zh) * 2022-05-17 2024-02-02 河南省科学院高新技术研究中心 一种利用离子液体制备1-甲基-1,2,3,4-四氢异喹啉的方法

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US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
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US4044136A (en) 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
GB1383409A (en) 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US3956495A (en) 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4755218A (en) 1985-12-31 1988-07-05 Monsanto Company Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
IL88507A (en) * 1987-12-03 1993-02-21 Smithkline Beckman Intercredit 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them
US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
DE3901448A1 (de) 1989-01-19 1990-07-26 Basf Ag Emulsionscopolymerisate
DK0388838T3 (da) 1989-03-22 1996-02-05 Ciba Geigy Ag Parasiticid
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
CA2015981A1 (en) * 1989-05-10 1990-11-10 Thomas H. Brown Compounds
GB9012592D0 (en) 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
DK0556310T3 (da) 1990-11-06 1995-08-21 Pfizer Quinazolinderivater til forhøjelse af antitumoraktivitet
EP0580753B1 (en) 1991-04-17 1995-03-01 Pfizer Inc. Pyrimidine derivatives for enhancing antitumor activity
US5276186A (en) 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
KR0144833B1 (ko) * 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
FI960628L (fi) * 1993-08-12 1996-02-12 Astra Ab Amidiinijohdannaisia, joilla on typpioksidisyntetaasiaktiivisuuksia
ATE163647T1 (de) 1993-08-26 1998-03-15 Ono Pharmaceutical Co 4-aminopyrimidin derivate
RU2153494C2 (ru) 1993-10-12 2000-07-27 Дзе Дюпон Мерк Фармасьютикал Компани 1-n-алкил-n-арилпиримидинамины, способ лечения заболеваний, фармацевтическая композиция
RU2129549C1 (ru) * 1994-08-13 1999-04-27 Юхан Корпорейшн Производные пиримидина и способы их получения
US5990311A (en) 1996-05-04 1999-11-23 Uhan Corporation Process for preparation of pyrimidine derivatives

Also Published As

Publication number Publication date
TR199902383T2 (xx) 2000-06-21
WO1998043968A1 (en) 1998-10-08
BR9808070A (pt) 2000-03-08
EP1015444B1 (en) 2003-05-28
RU2203894C2 (ru) 2003-05-10
HK1026418A1 (en) 2000-12-15
PT1015444E (pt) 2003-10-31
HUP0000851A3 (en) 2002-04-29
JP3176379B2 (ja) 2001-06-18
KR100278857B1 (ko) 2001-01-15
AU6523998A (en) 1998-10-22
CA2284795C (en) 2004-01-20
DE69815126T2 (de) 2004-04-08
DK1015444T3 (da) 2003-08-18
JP2000513014A (ja) 2000-10-03
CA2284795A1 (en) 1998-10-08
KR19980080789A (ko) 1998-11-25
UY24938A1 (es) 2001-01-31
DE69815126D1 (de) 2003-07-03
ES2200324T3 (es) 2004-03-01
EP1015444A1 (en) 2000-07-05
TW542831B (en) 2003-07-21
US6352993B1 (en) 2002-03-05
ATE241613T1 (de) 2003-06-15
AR012181A1 (es) 2000-09-27
CN1118464C (zh) 2003-08-20
HUP0000851A1 (hu) 2001-04-28
CN1251586A (zh) 2000-04-26
AU720385B2 (en) 2000-06-01

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