IN149973B - - Google Patents

Info

Publication number
IN149973B
IN149973B IN19/DEL/81A IN19DE1981A IN149973B IN 149973 B IN149973 B IN 149973B IN 19DE1981 A IN19DE1981 A IN 19DE1981A IN 149973 B IN149973 B IN 149973B
Authority
IN
India
Application number
IN19/DEL/81A
Other languages
English (en)
Inventor
S Campbell
J Danilewicz
A Evans
A Ham
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to IN19/DEL/81A priority Critical patent/IN149973B/en
Publication of IN149973B publication Critical patent/IN149973B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IN19/DEL/81A 1977-06-03 1981-01-13 IN149973B (cg-RX-API-DMAC10.html)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IN19/DEL/81A IN149973B (cg-RX-API-DMAC10.html) 1977-06-03 1981-01-13

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2358277 1977-06-03
IN364/DEL/78A IN148482B (cg-RX-API-DMAC10.html) 1977-06-03 1978-05-15
IN19/DEL/81A IN149973B (cg-RX-API-DMAC10.html) 1977-06-03 1981-01-13

Publications (1)

Publication Number Publication Date
IN149973B true IN149973B (cg-RX-API-DMAC10.html) 1982-06-19

Family

ID=10198020

Family Applications (3)

Application Number Title Priority Date Filing Date
IN364/DEL/78A IN148482B (cg-RX-API-DMAC10.html) 1977-06-03 1978-05-15
IN368/DEL/80A IN149550B (cg-RX-API-DMAC10.html) 1977-06-03 1980-05-20
IN19/DEL/81A IN149973B (cg-RX-API-DMAC10.html) 1977-06-03 1981-01-13

Family Applications Before (2)

Application Number Title Priority Date Filing Date
IN364/DEL/78A IN148482B (cg-RX-API-DMAC10.html) 1977-06-03 1978-05-15
IN368/DEL/80A IN149550B (cg-RX-API-DMAC10.html) 1977-06-03 1980-05-20

Country Status (29)

Country Link
US (1) US4289772A (cg-RX-API-DMAC10.html)
JP (1) JPS5416488A (cg-RX-API-DMAC10.html)
AR (2) AR222013A1 (cg-RX-API-DMAC10.html)
AT (2) AT362792B (cg-RX-API-DMAC10.html)
AU (1) AU505373B1 (cg-RX-API-DMAC10.html)
BE (1) BE867727A (cg-RX-API-DMAC10.html)
CA (1) CA1111850A (cg-RX-API-DMAC10.html)
DD (1) DD137355A5 (cg-RX-API-DMAC10.html)
DE (1) DE2824064A1 (cg-RX-API-DMAC10.html)
DK (1) DK248078A (cg-RX-API-DMAC10.html)
EG (1) EG13527A (cg-RX-API-DMAC10.html)
ES (4) ES470470A1 (cg-RX-API-DMAC10.html)
FI (1) FI781753A7 (cg-RX-API-DMAC10.html)
FR (1) FR2392986A1 (cg-RX-API-DMAC10.html)
GB (1) GB2000136B (cg-RX-API-DMAC10.html)
GR (1) GR74402B (cg-RX-API-DMAC10.html)
HU (1) HU179745B (cg-RX-API-DMAC10.html)
IL (1) IL54842A (cg-RX-API-DMAC10.html)
IN (3) IN148482B (cg-RX-API-DMAC10.html)
IT (1) IT1094944B (cg-RX-API-DMAC10.html)
LU (1) LU79761A1 (cg-RX-API-DMAC10.html)
NL (1) NL7806016A (cg-RX-API-DMAC10.html)
NO (1) NO781935L (cg-RX-API-DMAC10.html)
NZ (1) NZ187453A (cg-RX-API-DMAC10.html)
PL (3) PL113208B1 (cg-RX-API-DMAC10.html)
PT (1) PT68126A (cg-RX-API-DMAC10.html)
SE (1) SE7806519L (cg-RX-API-DMAC10.html)
SU (2) SU856383A3 (cg-RX-API-DMAC10.html)
ZA (1) ZA783183B (cg-RX-API-DMAC10.html)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
IL59619A0 (en) * 1979-03-28 1980-06-30 Pfizer Phthalazine derivatives,their preparation and pharmaceutical compositions containing them
PL129174B1 (en) * 1980-03-01 1984-04-30 Wyeth John & Brother Ltd Process for preparing novel derivatives of piperidine
GB8320958D0 (en) * 1983-08-03 1983-09-07 Pfizer Ltd Quinazoline cardiac stimulants
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
JP3169188B2 (ja) * 1991-01-31 2001-05-21 杏林製薬株式会社 カルバミン酸誘導体及びその製造方法
US5300515A (en) * 1991-01-31 1994-04-05 Kyorin Pharmaceutical Co., Ltd. Carbamic acid derivatives and method for preparing the same
EP0621267A1 (en) * 1993-04-07 1994-10-26 Shell Internationale Researchmaatschappij B.V. Spiropiperidine derivatives and their use as fungicides
US5728712A (en) * 1995-05-19 1998-03-17 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
CN1121220C (zh) * 1996-08-20 2003-09-17 卫材株式会社 稠合哒嗪系化合物的勃起机能不全症治疗剂
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
BR0313534A (pt) * 2002-08-16 2005-07-12 Janssen Pharmaceutica Nv Antagonistas de integrinade ácido carboxìlico de piperidinoìla
US20040224986A1 (en) * 2002-08-16 2004-11-11 Bart De Corte Piperidinyl targeting compounds that selectively bind integrins
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス,インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス,インコーポレイティド Pde阻害による神経新生の調節
JP2009513672A (ja) 2005-10-31 2009-04-02 ブレインセルス,インコーポレイティド 神経発生のgaba受容体媒介調節
BRPI0707223A2 (pt) * 2006-01-27 2011-04-26 Pfizer Prod Inc compostos de derivados de aminoftalazina
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US8247442B2 (en) 2006-03-29 2012-08-21 Purdue Pharma L.P. Benzenesulfonamide compounds and their use
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
WO2007118853A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and their use as blockers of calcium channels
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP1900731A1 (de) * 2006-09-07 2008-03-19 Bayer Schering Pharma Aktiengesellschaft N-(1-Phthalazin-1-yl-piperidin-4-yl)-amide als EP2-Rezeptor Modulatoren
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
MX2009002496A (es) 2006-09-08 2009-07-10 Braincells Inc Combinaciones que contienen un derivado de 4-acilaminopiridina.
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
JP2010535733A (ja) 2007-08-07 2010-11-25 エフ.ホフマン−ラ ロシュ アーゲー Nk3受容体アンタゴニストとしてのピロリジンアリールエーテル
BRPI0815674A2 (pt) 2007-08-22 2015-02-18 Hoffmann La Roche Aril-éter de pirrolidina como antagonista de receptor de nk3
BRPI0816971A2 (pt) * 2007-09-14 2015-03-24 Hoffmann La Roche Derivados de piperidina como antagonistas de receptor nk3
WO2009040659A2 (en) 2007-09-28 2009-04-02 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
AR077014A1 (es) * 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
CN116349204A (zh) 2020-10-13 2023-06-27 奋进生物医药公司 治疗纤维化的方法
CN113087654B (zh) * 2021-04-15 2022-12-23 苏州昊帆生物股份有限公司 哌啶-4-丁胺的制备方法
WO2025188802A1 (en) 2024-03-05 2025-09-12 Endeavor Biomedicines, Inc. Methods of improving lung function

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094044A (en) * 1965-07-12 1967-12-06 Vantorex Ltd Phthalazine derivatives
GB1199768A (en) 1966-10-31 1970-07-22 Pfizer & Co C Nitrogen Heterocycles and process for their preparation
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB1460389A (en) 1974-07-25 1977-01-06 Pfizer Ltd 4-substituted quinazoline cardiac stimulants

Also Published As

Publication number Publication date
GR74402B (cg-RX-API-DMAC10.html) 1984-06-28
ATA305080A (de) 1980-12-15
EG13527A (en) 1981-12-31
NO781935L (no) 1978-12-05
FI781753A7 (fi) 1978-12-04
PT68126A (en) 1978-07-01
NZ187453A (en) 1980-12-19
JPS5416488A (en) 1979-02-07
GB2000136A (en) 1979-01-04
ES478199A1 (es) 1980-01-16
CA1111850A (en) 1981-11-03
AT363096B (de) 1981-07-10
ZA783183B (en) 1979-06-27
LU79761A1 (fr) 1980-01-22
ATA400878A (de) 1980-11-15
DE2824064A1 (de) 1978-12-14
BE867727A (fr) 1978-12-01
FR2392986A1 (fr) 1978-12-29
SU856383A3 (ru) 1981-08-15
ES478200A1 (es) 1980-01-01
DK248078A (da) 1978-12-04
FR2392986B1 (cg-RX-API-DMAC10.html) 1982-07-16
IT1094944B (it) 1985-08-10
PL207337A1 (pl) 1979-06-04
DD137355A5 (de) 1979-08-29
AT362792B (de) 1981-06-10
IN149550B (cg-RX-API-DMAC10.html) 1982-01-16
AR222013A1 (es) 1981-04-15
AR223999A1 (es) 1981-10-15
GB2000136B (en) 1982-01-06
HU179745B (en) 1982-12-28
IN148482B (cg-RX-API-DMAC10.html) 1981-03-07
JPS5538351B2 (cg-RX-API-DMAC10.html) 1980-10-03
AU505373B1 (en) 1979-11-15
ES470470A1 (es) 1979-09-01
PL116420B1 (en) 1981-06-30
IL54842A (en) 1982-01-31
US4289772A (en) 1981-09-15
SU862826A3 (ru) 1981-09-07
PL113208B1 (en) 1980-11-29
ES478201A1 (es) 1980-02-01
PL116437B1 (en) 1981-06-30
IT7824106A0 (it) 1978-06-01
NL7806016A (nl) 1978-12-05
IL54842A0 (en) 1978-08-31
SE7806519L (sv) 1978-12-04

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