IL99567A - Concentrate of high-activity blood clotting factor IX, suitable for drug use, and its preparation - Google Patents

Concentrate of high-activity blood clotting factor IX, suitable for drug use, and its preparation

Info

Publication number
IL99567A
IL99567A IL9956791A IL9956791A IL99567A IL 99567 A IL99567 A IL 99567A IL 9956791 A IL9956791 A IL 9956791A IL 9956791 A IL9956791 A IL 9956791A IL 99567 A IL99567 A IL 99567A
Authority
IL
Israel
Prior art keywords
factor
process according
solution
sodium chloride
concentrate
Prior art date
Application number
IL9956791A
Other languages
English (en)
Hebrew (he)
Other versions
IL99567A0 (en
Original Assignee
Aetsrn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aetsrn filed Critical Aetsrn
Publication of IL99567A0 publication Critical patent/IL99567A0/xx
Publication of IL99567A publication Critical patent/IL99567A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6443—Coagulation factor XIa (3.4.21.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21027—Coagulation factor XIa (3.4.21.27)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
IL9956791A 1991-05-07 1991-09-25 Concentrate of high-activity blood clotting factor IX, suitable for drug use, and its preparation IL99567A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105572A FR2676231A1 (fr) 1991-05-07 1991-05-07 Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.

Publications (2)

Publication Number Publication Date
IL99567A0 IL99567A0 (en) 1992-08-18
IL99567A true IL99567A (en) 1996-01-19

Family

ID=9412593

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9956791A IL99567A (en) 1991-05-07 1991-09-25 Concentrate of high-activity blood clotting factor IX, suitable for drug use, and its preparation

Country Status (16)

Country Link
US (1) US5252217A (lt)
EP (1) EP0512883B1 (lt)
AT (1) ATE156360T1 (lt)
AU (1) AU652043B2 (lt)
BR (1) BR9201718A (lt)
CA (1) CA2068069C (lt)
DE (1) DE69221369T2 (lt)
DK (1) DK0512883T3 (lt)
EE (1) EE03017B1 (lt)
ES (1) ES2107511T3 (lt)
FR (1) FR2676231A1 (lt)
GR (1) GR3025134T3 (lt)
IL (1) IL99567A (lt)
LT (1) LT3417B (lt)
RU (1) RU2097047C1 (lt)
UA (1) UA27733C2 (lt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1304050C (zh) * 2001-07-20 2007-03-14 诺沃挪第克健康护理股份公司 含有因子ⅶ多肽和因子ⅺ多肽的药用组合物
US20030040480A1 (en) * 2001-07-20 2003-02-27 Rasmus Rojkjaer Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
BRPI0416461A (pt) * 2003-11-20 2007-03-06 Novo Nordisk Healthcare Ag método para o tratamento de episódios de sangramento, formulação farmacêutica, e, uso de um polipeptìdeo fxi
US20050181978A1 (en) * 2003-11-20 2005-08-18 Rasmus Rojkjaer Therapeutic use of factor XI
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
CL2007002615A1 (es) * 2006-09-08 2008-04-18 Wyeth Corp Metodos para aislar o purificar un producto que comprende poner el producto enlazado en contacto con al menos una solucion de lavado que comprende arginina y luego eluir el producto; y dicho producto.
ATE546520T1 (de) * 2007-01-04 2012-03-15 Crucell Holland Bv Faktor-xi-reinigung
JP5809058B2 (ja) * 2008-10-15 2015-11-10 アイシス ファーマシューティカルズ， インコーポレーテッド 第１１因子発現の調節
FR2974301B1 (fr) 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
FR2974366B1 (fr) 2011-04-20 2016-06-24 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur xi
IL212911A0 (en) 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
DE102012022233A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Verfahren zur Reinigung eines (Blut)plasmaproteins
DE102012022234A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Einstufiges Verfahren zur Reinigung von (Blut)Plasmaproteinen wie Albumin aus Gemischen
FR3032621A1 (fr) 2015-02-13 2016-08-19 Lab Francais Du Fractionnement Colle biologique et son utilisation comme medicament
KR101941974B1 (ko) * 2016-11-18 2019-01-24 주식회사 녹십자 혈장 단백질 정제시 fxi의 제거방법
JOP20200280A1 (ar) 2018-05-09 2020-11-05 Ionis Pharmaceuticals Inc مركبات وطرق لتقليل التعبير الوراثي عن fxi

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859340A (en) * 1976-03-15 1989-08-22 Cuno, Incorporated Filter sheet
US4783262A (en) * 1987-03-30 1988-11-08 Cuno Incorporated Separator for cell type filter element

Also Published As

Publication number Publication date
CA2068069A1 (en) 1992-11-08
DE69221369D1 (de) 1997-09-11
AU1526392A (en) 1992-11-12
IL99567A0 (en) 1992-08-18
FR2676231A1 (fr) 1992-11-13
AU652043B2 (en) 1994-08-11
UA27733C2 (uk) 2000-10-16
LTIP265A (en) 1994-10-25
FR2676231B1 (lt) 1995-04-21
DK0512883T3 (da) 1998-03-16
LT3417B (en) 1995-09-25
BR9201718A (pt) 1992-12-29
EP0512883B1 (fr) 1997-08-06
DE69221369T2 (de) 1998-03-19
GR3025134T3 (en) 1998-02-27
RU2097047C1 (ru) 1997-11-27
EE03017B1 (et) 1997-08-15
US5252217A (en) 1993-10-12
ES2107511T3 (es) 1997-12-01
ATE156360T1 (de) 1997-08-15
CA2068069C (en) 2005-03-15
EP0512883A1 (fr) 1992-11-11

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