DK0512883T3 - Fremgangsmåde til fremstilling af et koncentrat af blodkoaguleringsfaktor XI med høj specifik aktivitet, til terapeutisk anvendelse - Google Patents

Fremgangsmåde til fremstilling af et koncentrat af blodkoaguleringsfaktor XI med høj specifik aktivitet, til terapeutisk anvendelse

Info

Publication number
DK0512883T3
DK0512883T3 DK92401157.0T DK92401157T DK0512883T3 DK 0512883 T3 DK0512883 T3 DK 0512883T3 DK 92401157 T DK92401157 T DK 92401157T DK 0512883 T3 DK0512883 T3 DK 0512883T3
Authority
DK
Denmark
Prior art keywords
concentrate
specific activity
high specific
therapeutic use
preparing
Prior art date
Application number
DK92401157.0T
Other languages
Danish (da)
English (en)
Inventor
Nee Radosevich Miryana Burnouf
Dominique Dernis
Original Assignee
Ass Pour Lessor De La Transfus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ass Pour Lessor De La Transfus filed Critical Ass Pour Lessor De La Transfus
Application granted granted Critical
Publication of DK0512883T3 publication Critical patent/DK0512883T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6443—Coagulation factor XIa (3.4.21.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21027—Coagulation factor XIa (3.4.21.27)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK92401157.0T 1991-05-07 1992-04-23 Fremgangsmåde til fremstilling af et koncentrat af blodkoaguleringsfaktor XI med høj specifik aktivitet, til terapeutisk anvendelse DK0512883T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105572A FR2676231A1 (fr) 1991-05-07 1991-05-07 Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.

Publications (1)

Publication Number Publication Date
DK0512883T3 true DK0512883T3 (da) 1998-03-16

Family

ID=9412593

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92401157.0T DK0512883T3 (da) 1991-05-07 1992-04-23 Fremgangsmåde til fremstilling af et koncentrat af blodkoaguleringsfaktor XI med høj specifik aktivitet, til terapeutisk anvendelse

Country Status (16)

Country Link
US (1) US5252217A (lt)
EP (1) EP0512883B1 (lt)
AT (1) ATE156360T1 (lt)
AU (1) AU652043B2 (lt)
BR (1) BR9201718A (lt)
CA (1) CA2068069C (lt)
DE (1) DE69221369T2 (lt)
DK (1) DK0512883T3 (lt)
EE (1) EE03017B1 (lt)
ES (1) ES2107511T3 (lt)
FR (1) FR2676231A1 (lt)
GR (1) GR3025134T3 (lt)
IL (1) IL99567A (lt)
LT (1) LT3417B (lt)
RU (1) RU2097047C1 (lt)
UA (1) UA27733C2 (lt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030040480A1 (en) * 2001-07-20 2003-02-27 Rasmus Rojkjaer Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
JP2004534855A (ja) * 2001-07-20 2004-11-18 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 第ｖｉｉ因子ポリペプチドおよび第ｘｉ因子ポリペプチドを含んでなる医薬組成物
US20050181978A1 (en) * 2003-11-20 2005-08-18 Rasmus Rojkjaer Therapeutic use of factor XI
BRPI0416461A (pt) * 2003-11-20 2007-03-06 Novo Nordisk Healthcare Ag método para o tratamento de episódios de sangramento, formulação farmacêutica, e, uso de um polipeptìdeo fxi
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
EP2059258B1 (en) * 2006-09-08 2019-11-13 Wyeth LLC Arginine wash in protein purification using affinity chromatography
EP2102335B1 (en) * 2007-01-04 2012-02-22 Crucell Holland B.V. Purification of factor xi
EP3335715A3 (en) 2008-10-15 2018-08-08 Ionis Pharmaceuticals, Inc. Modulation of factor 11 expression
FR2974301B1 (fr) 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
FR2974366B1 (fr) 2011-04-20 2016-06-24 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur xi
IL212911A0 (en) 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
DE102012022233A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Verfahren zur Reinigung eines (Blut)plasmaproteins
DE102012022234A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Einstufiges Verfahren zur Reinigung von (Blut)Plasmaproteinen wie Albumin aus Gemischen
FR3032621A1 (fr) 2015-02-13 2016-08-19 Lab Francais Du Fractionnement Colle biologique et son utilisation comme medicament
KR101941974B1 (ko) * 2016-11-18 2019-01-24 주식회사 녹십자 혈장 단백질 정제시 fxi의 제거방법
JOP20200280A1 (ar) 2018-05-09 2020-11-05 Ionis Pharmaceuticals Inc مركبات وطرق لتقليل التعبير الوراثي عن fxi

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859340A (en) * 1976-03-15 1989-08-22 Cuno, Incorporated Filter sheet
US4783262A (en) * 1987-03-30 1988-11-08 Cuno Incorporated Separator for cell type filter element

Also Published As

Publication number Publication date
LT3417B (en) 1995-09-25
FR2676231A1 (fr) 1992-11-13
LTIP265A (en) 1994-10-25
IL99567A0 (en) 1992-08-18
EP0512883A1 (fr) 1992-11-11
UA27733C2 (uk) 2000-10-16
AU1526392A (en) 1992-11-12
EE03017B1 (et) 1997-08-15
DE69221369D1 (de) 1997-09-11
RU2097047C1 (ru) 1997-11-27
AU652043B2 (en) 1994-08-11
ATE156360T1 (de) 1997-08-15
EP0512883B1 (fr) 1997-08-06
DE69221369T2 (de) 1998-03-19
IL99567A (en) 1996-01-19
CA2068069A1 (en) 1992-11-08
ES2107511T3 (es) 1997-12-01
FR2676231B1 (lt) 1995-04-21
GR3025134T3 (en) 1998-02-27
US5252217A (en) 1993-10-12
CA2068069C (en) 2005-03-15
BR9201718A (pt) 1992-12-29

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