IL99472A - History 4 (5) -Imidazolyl - diphenylalkyl and diphenylalkanol inhibiting aromatase and pharmaceutical preparations containing them - Google Patents

History 4 (5) -Imidazolyl - diphenylalkyl and diphenylalkanol inhibiting aromatase and pharmaceutical preparations containing them

Info

Publication number
IL99472A
IL99472A IL9947291A IL9947291A IL99472A IL 99472 A IL99472 A IL 99472A IL 9947291 A IL9947291 A IL 9947291A IL 9947291 A IL9947291 A IL 9947291A IL 99472 A IL99472 A IL 99472A
Authority
IL
Israel
Prior art keywords
compounds
formula
imidazole
halogen
compound
Prior art date
Application number
IL9947291A
Other languages
English (en)
Hebrew (he)
Other versions
IL99472A0 (en
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of IL99472A0 publication Critical patent/IL99472A0/xx
Publication of IL99472A publication Critical patent/IL99472A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
IL9947291A 1990-09-21 1991-09-13 History 4 (5) -Imidazolyl - diphenylalkyl and diphenylalkanol inhibiting aromatase and pharmaceutical preparations containing them IL99472A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9020629A GB2248058B (en) 1990-09-21 1990-09-21 Aromatase inhibiting 4(5)-imidazoles

Publications (2)

Publication Number Publication Date
IL99472A0 IL99472A0 (en) 1992-08-18
IL99472A true IL99472A (en) 1995-11-27

Family

ID=10682560

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9947291A IL99472A (en) 1990-09-21 1991-09-13 History 4 (5) -Imidazolyl - diphenylalkyl and diphenylalkanol inhibiting aromatase and pharmaceutical preparations containing them

Country Status (20)

Country Link
EP (1) EP0476944B1 (xx)
JP (1) JPH04230668A (xx)
AT (1) ATE130295T1 (xx)
AU (1) AU640817B2 (xx)
CA (1) CA2051803A1 (xx)
CZ (1) CZ280088B6 (xx)
DE (1) DE69114644T2 (xx)
FI (1) FI914254A (xx)
GB (1) GB2248058B (xx)
HU (1) HUT59107A (xx)
IE (1) IE68934B1 (xx)
IL (1) IL99472A (xx)
LT (1) LT3441B (xx)
LV (1) LV10095B (xx)
NO (1) NO913712L (xx)
NZ (1) NZ239800A (xx)
PL (1) PL167741B1 (xx)
PT (1) PT99019A (xx)
RU (1) RU2036193C1 (xx)
ZA (1) ZA917476B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9125924D0 (en) * 1991-06-18 1992-02-05 Orion Yhtymae Oy Stereoisomers of an imidazole derivative
GB9224144D0 (en) * 1992-11-18 1993-01-06 Erba Carlo Spa Phenyl-imidazolidinone derivatives and process for their preparation
WO2009082268A2 (ru) * 2007-12-21 2009-07-02 Alla Chem, Llc ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605661A (en) * 1984-06-18 1986-08-12 Eli Lilly And Company Aromastase inhibiting α,α-diarylimidazole-4(5)-propionitriles, α,α-diarylimidazole-4(5)-propionamides, and 4(5)-(2,2-diarylethyl)imidazoles
LU85747A1 (fr) * 1985-01-28 1986-08-04 Continental Pharma Derives d'imidazole leur preparation et utilisation ainsi que les compositions pharmaceutiques contenant des derives
GB2210875B (en) * 1987-10-09 1991-05-29 Farmos Oy Aromatase inhibiting 4(5)-imidazoles
GB8818561D0 (en) * 1988-08-04 1988-09-07 Ici Plc Diphenylethane derivatives
GB2229719B (en) * 1989-03-30 1992-04-29 Farmos Oy Novel aromatase inhibiting 4(5)-imidazoles
JPH032168A (ja) * 1989-03-30 1991-01-08 Farmos Yhtymae Oy アロマターゼ阻害活性を有する新規な４（５）―イミダゾール
GB2231568B (en) * 1989-03-31 1992-07-08 Farmos Oy New aromatase inhibiting 4(5)-imidazoles

Also Published As

Publication number Publication date
CZ280088B6 (cs) 1995-10-18
PL167741B1 (pl) 1995-10-31
JPH04230668A (ja) 1992-08-19
GB2248058B (en) 1994-09-14
LV10095B (en) 1995-02-20
ZA917476B (en) 1992-05-27
PT99019A (pt) 1992-08-31
IL99472A0 (en) 1992-08-18
HU913019D0 (en) 1992-01-28
DE69114644T2 (de) 1996-05-15
GB9020629D0 (en) 1990-10-31
CA2051803A1 (en) 1992-03-22
FI914254A0 (fi) 1991-09-10
NO913712D0 (no) 1991-09-20
DE69114644D1 (de) 1995-12-21
ATE130295T1 (de) 1995-12-15
NO913712L (no) 1992-03-23
EP0476944A1 (en) 1992-03-25
GB2248058A (en) 1992-03-25
NZ239800A (en) 1993-11-25
IE913314A1 (en) 1992-02-25
CS286891A3 (en) 1992-04-15
AU8382691A (en) 1992-04-09
IE68934B1 (en) 1996-07-24
FI914254A (fi) 1992-03-22
LT3441B (en) 1995-10-25
LTIP582A (en) 1994-12-27
LV10095A (lv) 1994-05-10
RU2036193C1 (ru) 1995-05-27
PL291747A1 (en) 1992-10-19
EP0476944B1 (en) 1995-11-15
HUT59107A (en) 1992-04-28
AU640817B2 (en) 1993-09-02

Similar Documents

Publication Publication Date Title
US5098923A (en) Aromatase inhibiting 4(5)-imidazoles
EP0674626B1 (en) Selective aromatase inhibiting compounds
EP0371805A2 (en) Piperidine derivatives and hypotensives containing the same
IL102216A (en) 4) 5 (-Amidazoles and aromatase-inhibiting pharmaceutical preparations with selectivity containing them
IL99472A (en) History 4 (5) -Imidazolyl - diphenylalkyl and diphenylalkanol inhibiting aromatase and pharmaceutical preparations containing them
RU1836354C (ru) Способ получени замещенного имидазола или его нетоксичной фармацевтически приемлемой кислотно-аддитивной соли
GB2231568A (en) New aromatase inhibiting 4(5)-imidazoles
PL162554B1 (pl) S posób wytwarzania nowych pochodnych imidazolu PL PL PL PL PL
IL107260A (en) Diphenylalkyl 4) 5 (- Imidazoles that inhibit aromatase and medicinal preparations containing them

Legal Events

Date Code Title Description
FF Patent granted
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees