GB2231568B - New aromatase inhibiting 4(5)-imidazoles - Google Patents

New aromatase inhibiting 4(5)-imidazoles

Info

Publication number
GB2231568B
GB2231568B GB8907309A GB8907309A GB2231568B GB 2231568 B GB2231568 B GB 2231568B GB 8907309 A GB8907309 A GB 8907309A GB 8907309 A GB8907309 A GB 8907309A GB 2231568 B GB2231568 B GB 2231568B
Authority
GB
United Kingdom
Prior art keywords
imidazoles
aromatase inhibiting
new
new aromatase
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
GB8907309A
Other versions
GB8907309D0 (en
GB2231568A (en
Inventor
Arto Johannes Karjalainen
Reino Pelkonen Olavi
Arja Leena Karjalainen
Matti Antero Lahde
Risto Arvo Sakari Lammintausta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmos Yhtyma Oy
Original Assignee
Farmos Yhtyma Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Yhtyma Oy filed Critical Farmos Yhtyma Oy
Priority to GB8907309A priority Critical patent/GB2231568B/en
Publication of GB8907309D0 publication Critical patent/GB8907309D0/en
Priority to CS92593A priority patent/CZ281546B6/en
Priority to FI901317A priority patent/FI901317A0/en
Priority to JP2080548A priority patent/JPH032168A/en
Priority to AU52325/90A priority patent/AU627559B2/en
Priority to DE69012184T priority patent/DE69012184T2/en
Priority to HU901894A priority patent/HU205345B/en
Priority to IE115290A priority patent/IE64655B1/en
Priority to NO901451A priority patent/NO172797C/en
Priority to UA4895673A priority patent/UA13471A/en
Priority to HU914010A priority patent/HU206685B/en
Priority to IL9394090A priority patent/IL93940A/en
Priority to EP90303362A priority patent/EP0390558B1/en
Priority to CS901555A priority patent/CZ281611B6/en
Priority to ES90303362T priority patent/ES2063260T3/en
Priority to IL10726090A priority patent/IL107260A/en
Priority to NZ233127A priority patent/NZ233127A/en
Priority to AT90303362T priority patent/ATE111084T1/en
Priority to DK90303362.9T priority patent/DK0390558T3/en
Priority to PT93606A priority patent/PT93606B/en
Priority to PL28896490A priority patent/PL162556B1/en
Priority to CN90102676A priority patent/CN1046527A/en
Priority to PL28455290A priority patent/PL162513B1/en
Priority to PL28896390A priority patent/PL162555B1/en
Publication of GB2231568A publication Critical patent/GB2231568A/en
Priority to NO911040A priority patent/NO172119C/en
Priority to SU914895631A priority patent/RU2067578C1/en
Priority to SU914895673A priority patent/RU1836354C/en
Application granted granted Critical
Publication of GB2231568B publication Critical patent/GB2231568B/en
Priority to US08/063,471 priority patent/US5439928A/en
Priority to CN93108897A priority patent/CN1086812A/en
Priority to IL107260A priority patent/IL107260A0/en
Priority to LVP-95-273A priority patent/LV11027B/en
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB8907309A 1989-03-30 1989-03-31 New aromatase inhibiting 4(5)-imidazoles Revoked GB2231568B (en)

Priority Applications (31)

Application Number Priority Date Filing Date Title
GB8907309A GB2231568B (en) 1989-03-31 1989-03-31 New aromatase inhibiting 4(5)-imidazoles
CS92593A CZ281546B6 (en) 1989-03-31 1990-02-07 Novel aromatase inhibiting 4/5/-diarylalkylimidazoles
FI901317A FI901317A0 (en) 1989-03-31 1990-03-16 FREQUENCY REFRIGERATION FOR NY 4 (5) -IMIDAZOLER.
JP2080548A JPH032168A (en) 1989-03-30 1990-03-28 Novel 4 (5)-imidazole having aromatase inhibitive activity
AU52325/90A AU627559B2 (en) 1989-03-30 1990-03-28 Novel aromatase inhibiting 4(5)-imidazoles
NZ233127A NZ233127A (en) 1989-03-30 1990-03-29 Imidazole derivatives and pharmaceutical compositions
HU901894A HU205345B (en) 1989-03-30 1990-03-29 Process for producing new 4(5)-imidazole derivatives
IE115290A IE64655B1 (en) 1989-03-30 1990-03-29 Novel aromatase inhibiting 4(5)-imidazoles
NO901451A NO172797C (en) 1989-03-30 1990-03-29 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE SUBSTITUTED IMIDAZOLE COMPOUNDS
UA4895673A UA13471A (en) 1989-03-30 1990-03-29 METHOD OF OBTAINING SUBSTITUTED IMIDAZOLE OR ITS NON-TOXIC PHARMACEUTICALLY ACCEPTABLE ACID-ADDITIVE SALT
HU914010A HU206685B (en) 1989-03-30 1990-03-29 Process for producing new 4/5/-imidazol derivatives
IL9394090A IL93940A (en) 1989-03-30 1990-03-29 Aromatase inhibiting diphenylalkyl 4(5)-imidazoles and pharmaceutical compositions containing them
EP90303362A EP0390558B1 (en) 1989-03-30 1990-03-29 Aromatase inhibiting 4(5)-imidazoles
CS901555A CZ281611B6 (en) 1989-03-30 1990-03-29 4(5)-diarylalkylimidazole derivatives, process of their preparation, pharmaceutical preparatin in which said derivatives are comprised and their use
ES90303362T ES2063260T3 (en) 1989-03-30 1990-03-29 NEW 4 (5) -IMIDAZOLES INHIBITORS OF AROMATASE.
IL10726090A IL107260A (en) 1989-03-30 1990-03-29 Aromatase inhibiting diphenylalkyl 4(5)-imidazoles and pharmaceutical compositions containing them
DE69012184T DE69012184T2 (en) 1989-03-30 1990-03-29 Aromatase inhibiting 4 (5) imidazoles.
AT90303362T ATE111084T1 (en) 1989-03-30 1990-03-29 AROMATASE INHIBITING 4(5)-IMIDAZOLE.
DK90303362.9T DK0390558T3 (en) 1989-03-30 1990-03-29 Aromatase inhibitor 4 (5) -imidazoles
PT93606A PT93606B (en) 1989-03-30 1990-03-29 METHOD FOR PREPARING NEW 4 (5) -IMIDAZOES THAT INHIBIT THE AROMATASE
PL28896490A PL162556B1 (en) 1989-03-31 1990-03-30 Method of obtaining novel derivatives of imidazole
PL28896390A PL162555B1 (en) 1989-03-31 1990-03-30 Method of obtaining novel derivatives of imidazole
CN90102676A CN1046527A (en) 1989-03-30 1990-03-30 Novel aromatization enzyme inhibitor 4 (5)-imidazoles
PL28455290A PL162513B1 (en) 1989-03-30 1990-03-30 Method for manufacturing new derivatives of imidazol
NO911040A NO172119C (en) 1989-03-30 1991-03-15 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE SUBSTITUTED IMIDAZOLE COMPOUNDS
SU914895631A RU2067578C1 (en) 1989-03-31 1991-06-19 Method of synthesis of substituted imidazoles or their pharmaceutical acceptable acid additive salts
SU914895673A RU1836354C (en) 1989-03-30 1991-06-25 Method for obtaining substituted imidazole or its nontoxic pharmaceutically acceptable acid-additive salt
US08/063,471 US5439928A (en) 1989-03-30 1993-05-19 Aromatase inhibiting 4(5)-imidazoles
CN93108897A CN1086812A (en) 1989-03-30 1993-07-14 The preparation method of novel aromatization enzyme inhibitor 4 (5)-imidazoles
IL107260A IL107260A0 (en) 1989-03-30 1993-10-12 Aromatase inhibiting diphenylalkyl 4(5)-imidazoles and pharmaceutical compositions containing them
LVP-95-273A LV11027B (en) 1989-03-30 1995-09-07 Aromatase inhibiting 4(5)-imidazoles aromatase inhibiting 4(5)-imidazoles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8907309A GB2231568B (en) 1989-03-31 1989-03-31 New aromatase inhibiting 4(5)-imidazoles

Publications (3)

Publication Number Publication Date
GB8907309D0 GB8907309D0 (en) 1989-05-17
GB2231568A GB2231568A (en) 1990-11-21
GB2231568B true GB2231568B (en) 1992-07-08

Family

ID=10654267

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8907309A Revoked GB2231568B (en) 1989-03-30 1989-03-31 New aromatase inhibiting 4(5)-imidazoles

Country Status (5)

Country Link
CZ (1) CZ281546B6 (en)
FI (1) FI901317A0 (en)
GB (1) GB2231568B (en)
PL (2) PL162556B1 (en)
RU (1) RU2067578C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2248058B (en) * 1990-09-21 1994-09-14 Orion Yhtymae Oy Aromatase inhibiting 4(5)-imidazoles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chemical Abstracts, vol. 57, abstract no 15120d-f *

Also Published As

Publication number Publication date
CZ59392A3 (en) 1996-07-17
FI901317A0 (en) 1990-03-16
PL162555B1 (en) 1993-12-31
CZ281546B6 (en) 1996-11-13
PL288964A1 (en) 1991-10-21
PL288963A1 (en) 1991-10-21
PL162556B1 (en) 1993-12-31
GB8907309D0 (en) 1989-05-17
RU2067578C1 (en) 1996-10-10
GB2231568A (en) 1990-11-21

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Legal Events

Date Code Title Description
773K Patent revoked under sect. 73(2)/1977