IL99285A - Propellant-free inhalation device - Google Patents

Propellant-free inhalation device

Info

Publication number
IL99285A
IL99285A IL9928591A IL9928591A IL99285A IL 99285 A IL99285 A IL 99285A IL 9928591 A IL9928591 A IL 9928591A IL 9928591 A IL9928591 A IL 9928591A IL 99285 A IL99285 A IL 99285A
Authority
IL
Israel
Prior art keywords
substance
propellant
dose
button
powdered substance
Prior art date
Application number
IL9928591A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of IL99285A publication Critical patent/IL99285A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0096Hindering inhalation before activation of the dispenser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • A61M2205/071General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicinal Preparation (AREA)
  • Lasers (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Sorption Type Refrigeration Machines (AREA)
  • Feeding And Controlling Fuel (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • External Artificial Organs (AREA)
  • Treating Waste Gases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nozzles (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Cosmetics (AREA)
  • Engine Equipment That Uses Special Cycles (AREA)
IL9928591A 1990-08-30 1991-08-23 Propellant-free inhalation device IL99285A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4027391A DE4027391A1 (de) 1990-08-30 1990-08-30 Treibgasfreies inhalationsgeraet
PCT/EP1991/001593 WO1992004068A1 (de) 1990-08-30 1991-08-22 Treibgasfreies inhalationsgerät mit fremdluftstrom

Publications (1)

Publication Number Publication Date
IL99285A true IL99285A (en) 1995-12-31

Family

ID=6413200

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9928591A IL99285A (en) 1990-08-30 1991-08-23 Propellant-free inhalation device

Country Status (26)

Country Link
US (1) US5617845A (sk)
EP (1) EP0549605B1 (sk)
JP (1) JP2505339B2 (sk)
KR (1) KR0179376B1 (sk)
AT (1) ATE116558T1 (sk)
AU (1) AU654499B2 (sk)
CA (1) CA2090227C (sk)
CZ (1) CZ281264B6 (sk)
DE (2) DE4027391A1 (sk)
DK (1) DK0549605T3 (sk)
EE (1) EE03092B1 (sk)
ES (1) ES2066463T3 (sk)
FI (1) FI105078B (sk)
GR (1) GR3015540T3 (sk)
HU (1) HU213661B (sk)
IE (1) IE71162B1 (sk)
IL (1) IL99285A (sk)
LT (1) LT3125B (sk)
LV (1) LV10398B (sk)
NO (1) NO304353B1 (sk)
NZ (1) NZ239530A (sk)
PL (1) PL166852B1 (sk)
RU (1) RU2098144C1 (sk)
SK (1) SK278886B6 (sk)
WO (1) WO1992004068A1 (sk)
ZA (1) ZA916741B (sk)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2087911T3 (es) * 1989-04-28 1996-08-01 Riker Laboratories Inc Dispositivo de inhalacion de polvo seco.
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
DE4133274A1 (de) * 1991-08-22 1993-02-25 Boehringer Ingelheim Kg Vorrichtung zum atemzugsynchronen ausloesen eines mechanischen schaltvorganges
DK0601071T3 (da) * 1991-08-26 2000-04-03 Minnesota Mining & Mfg Pulverdispenser
US6119688A (en) * 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
EP0632734B1 (en) * 1992-03-25 1998-06-10 Tebro S.A. Powder jet dispenser for medicament inhalation therapies
DK0572969T3 (sk) * 1992-06-05 1997-02-24 Hoechst Ag
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
AU5595694A (en) * 1992-11-12 1994-06-08 Minnesota Mining And Manufacturing Company Powder inhaler
FR2700279B1 (fr) * 1993-01-14 1995-03-17 Valois Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé.
FR2701653B1 (fr) * 1993-02-18 1995-04-07 Valois Dispositif doseur pour l'inhalation de poudre sèche.
DE4319514C2 (de) * 1993-06-14 2003-06-18 Sofotec Gmbh & Co Kg Pulverinhalator
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
FR2718968B1 (fr) * 1994-04-20 1996-07-26 Valois Sa Insert délimitant une chambre de dosage d'un inhalateur.
FI95441C (fi) * 1994-05-31 1996-02-12 Leiras Oy Inhalointilaitteen lääkeainekammio
SI9620081B (en) * 1995-06-21 2001-06-30 Asta Medica Ag Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments
DE19522415C2 (de) * 1995-06-21 2003-12-04 Sofotec Gmbh & Co Kg Arzneimittelpulverpatrone mit integrierter Dosiereinrichtung und Pulverinhalator mit Mitteln zum Betätigen der Dosiereinrichtung der Arzneimittelpulverpatrone
JP3317823B2 (ja) * 1995-08-11 2002-08-26 株式会社ユニシアジェックス 投薬器
FR2738153B1 (fr) * 1995-09-04 1998-01-02 Valois Appareil d'inhalation destine a distribuer des doses precises et reproductibles de produit pulverulent
SE9700936D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
SE9700937D0 (sv) 1997-03-14 1997-03-14 Astra Ab Powder inhaler I
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
SE9700935D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
GB9719093D0 (en) 1997-09-10 1997-11-12 Ml Lab Plc Improvements to dry powder inhalers
NZ504021A (en) * 1997-10-17 2003-04-29 Systemic Pulmonary Delivery Lt Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication
DE19825434C2 (de) * 1998-01-30 2002-03-28 Ig Spruehtechnik Gmbh Inhalationsgerät für pulverförmige Medikamente
AU742962B2 (en) 1998-01-30 2002-01-17 Mibe Gmbh Arzneimittel Inhalation apparatus for powder medications
US6223746B1 (en) * 1998-02-12 2001-05-01 Iep Pharmaceutical Devices Inc. Metered dose inhaler pump
PL343276A1 (en) 1998-03-16 2001-08-13 Inhale Therapeutic Syst Aerosolized active agent delivery
US6260549B1 (en) 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
EP1089783B1 (de) 1998-06-22 2004-09-29 AstraZeneca AB Vorrichtung zum leersaugen pulverenthaltender kavitäten
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
FI990915A0 (fi) * 1999-04-23 1999-04-23 Orion Yhtymae Oyj Jauheinhalaattori
CA2725731A1 (en) * 1999-06-05 2000-12-14 Innovata Biomed Limited Delivery system
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB9920839D0 (en) * 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
US6626171B2 (en) 2000-05-12 2003-09-30 Iep Pharmaceutical Devices Inc. Powder/liquid metering valve
GB0015043D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
WO2002013897A2 (en) 2000-08-14 2002-02-21 Advanced Inhalation Research, Inc. Inhalation device and method
DE10047722A1 (de) 2000-09-27 2002-04-11 Schuckmann Alfred Von Von Saugluftstrom des Benutzers aktivierbare Dosiervorrichtung
US20110301569A1 (en) 2001-01-20 2011-12-08 Gordon Wayne Dyer Methods and apparatus for the CVCS
BR0207062A (pt) * 2001-02-06 2004-10-05 Innovata Biomed Ltd Composição farmacêutica bimodal, inalador para pó seco, método de aplicação de uma quantidade terapeuticamente eficaz de um ingrediente ativo substancialmente fino aos pulmões de um paciente, método de tratamento de um distúrbio respiratório, método de tratamento de doença pulmonar obstrutiva crÈnica (copd), uso de um agente antiinflamatório, uso de um broncodilatador, uso de uma mistura de um agente antiinflamatório e de um broncodilatador, e, processo para a fabricação de uma composição farmacêutica bimodal
US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
FI20011317A0 (fi) * 2001-06-20 2001-06-20 Orion Corp Jauheinhalaattori
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10165101B3 (de) * 2001-09-11 2014-02-13 Sanofi Sa Inhalator für pulverförmige, insbesondere medizinische Substanzen
DE10144572B4 (de) * 2001-09-11 2013-08-01 Sanofi Sa Inhalator für pulverförmige, insbesondere medizinische Substanzen
DE10165112B3 (de) * 2001-09-11 2013-08-01 Sanofi Sa Inhalator für pulverförmige, insbesondere medizinische Substanzen
GB0128148D0 (en) * 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
US7258118B2 (en) 2002-01-24 2007-08-21 Sofotec Gmbh & Co, Kg Pharmaceutical powder cartridge, and inhaler equipped with same
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
EP1905474A3 (de) 2002-09-16 2008-04-16 von Schuckmann, Alfred Inhalator für pulverförmige, insbesondere medizinische Substanzen
EP1539286B1 (de) 2002-09-16 2015-01-21 Sanofi SA Inhalator für pulverförmige, insbesondere medizinische substanzen
FR2849386B1 (fr) * 2002-12-27 2005-03-18 Bertin Technologies Sa Dispositif d'inhalation de poudre seche
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
GB0407627D0 (en) * 2004-04-02 2004-05-05 Vectura Ltd Corkscrew pump
CA2562386C (en) * 2004-04-21 2014-11-18 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
PL1891974T3 (pl) 2004-05-31 2010-12-31 Almirall Sa Kombinacje zawierające środki przeciwmuskarynowe i inhibitory PDE4
ES2257152B1 (es) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
MX2007000592A (es) 2004-07-16 2008-03-04 Almirall Lab Inhalador para la administracion de farmaceuticos en polvo, y un sistema de cartuchos de polvo para uso con este inhalador.
ES2265276B1 (es) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
DE102005033397A1 (de) 2005-07-18 2007-01-25 Alfred Von Schuckmann Inhalator für pulverförmige, insbesondere medizinische Substanzen
GB2433207B (en) 2006-02-21 2009-01-07 Jianhe Li Active suction actuated inhalers with timing devices
DE102006029753A1 (de) 2006-03-10 2007-09-13 Alfred Von Schuckmann Inhalator für pulverförmige Substanzen
GB0614621D0 (en) * 2006-07-24 2006-08-30 3M Innovative Properties Co Metered dose dispensers
DE102006044752A1 (de) 2006-09-20 2008-04-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Kolbendosierer
WO2008056370A2 (en) * 2006-11-19 2008-05-15 Aespira Ltd. Dry-powder inhaler
CA2673553C (en) 2006-12-22 2014-06-17 Laboratorios Almirall, S.A. Breath actuated metering slide for a powder inhaler
ES2306595B1 (es) 2007-02-09 2009-09-11 Laboratorios Almirall S.A. Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.
WO2008101991A1 (en) * 2007-02-21 2008-08-28 Novo Nordisk A/S Breath actuation mechanism for an aerosol generating device
ES2320955B1 (es) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
WO2008156586A2 (en) * 2007-06-12 2008-12-24 Alkermes, Inc. Inhalation device for powdered substances
EP2042208A1 (en) * 2007-09-25 2009-04-01 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
DE102007053590A1 (de) * 2007-11-09 2009-05-14 Astra Zeneca Ab Handgerät zum Inhalieren von Substanzen
DE102007056263A1 (de) * 2007-11-22 2009-05-28 Siegfried Generics International Ag Dosiervorrichtung zur Inhalierung einer pulverförmigen Substanz
ES2320961B1 (es) 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2.
WO2009068617A1 (en) 2007-11-30 2009-06-04 Boehringer Ingelheim International Gmbh 1, 5-dihydro-pyrazolo (3, 4-d) pyrimidin-4-one derivatives and their use as pde9a modulators for the teatment of cns disorders
EP2534958A1 (en) 2007-12-14 2012-12-19 AeroDesigns, Inc Delivering aerosolizable food products
EP2096105A1 (en) 2008-02-28 2009-09-02 Laboratorios Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
UA105362C2 (en) 2008-04-02 2014-05-12 Бьорингер Ингельхайм Интернациональ Гмбх 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
EP2108641A1 (en) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
US8517009B2 (en) * 2008-07-13 2013-08-27 Map Pharmaceuticals, Inc. Methods and apparatus for delivering aerosolized medication
NZ590788A (en) 2008-09-08 2012-11-30 Boehringer Ingelheim Int Pyrazolopyrimidines and their use for the treatment of cns disorders
US8109414B2 (en) 2008-10-07 2012-02-07 Ing. Erich Pfeiffer Gmbh Discharge device
EP2196465A1 (en) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
EP2201977A1 (de) * 2008-12-23 2010-06-30 Siegfried Generics International AG Dosiervorrichtung zur Erzeugung eines Gasstromes mit einem in diesem fein verteilten Wirkstoff
EP2221297A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases
EP2221055A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function
EP2226323A1 (en) 2009-02-27 2010-09-08 Almirall, S.A. New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives
EP2228368A1 (en) 2009-03-12 2010-09-15 Almirall, S.A. Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
ES2460019T3 (es) 2009-03-31 2014-05-13 Boehringer Ingelheim International Gmbh Derivados de 1-heterociclil-1,5-dihidro-pirazolo[3,4-d]pirimidin-4-ona y su uso como moduladores de PDE9A
EP2322176A1 (en) 2009-11-11 2011-05-18 Almirall, S.A. New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives
EP2380890A1 (en) 2010-04-23 2011-10-26 Almirall, S.A. New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors
EP2386555A1 (en) 2010-05-13 2011-11-16 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities
EP2394998A1 (en) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
HUE033378T2 (en) 2010-08-12 2017-11-28 Boehringer Ingelheim Int 6-Cycloalkyl-1,5-dihydro-pyrazolo [3,4-D] pyrimidin-4-one and their use as PDE9A inhibitors
KR101857834B1 (ko) * 2010-09-06 2018-05-14 키에시 파르마슈티시 엣스. 피. 에이. 계량된-투여량 흡입기 액츄에이터, 계량된-투여량 흡입기
EP2441755A1 (en) 2010-09-30 2012-04-18 Almirall, S.A. Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
EP2463289A1 (en) 2010-11-26 2012-06-13 Almirall, S.A. Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors
US8809345B2 (en) 2011-02-15 2014-08-19 Boehringer Ingelheim International Gmbh 6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders
EP2489663A1 (en) 2011-02-16 2012-08-22 Almirall, S.A. Compounds as syk kinase inhibitors
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
EP2518071A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Imidazopyridine derivatives as PI3K inhibitors
EP2518070A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Pyrrolotriazinone derivatives as PI3K inhibitors
EP2527344A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases
EP2526945A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. New CRTH2 Antagonists
EP2548863A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists.
EP2548876A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists
EP2554544A1 (en) 2011-08-01 2013-02-06 Almirall, S.A. Pyridin-2(1h)-one derivatives as jak inhibitors
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2592077A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
EP2592078A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
EP2647627A1 (en) 2012-04-02 2013-10-09 Almirall, S.A. Salts of 5-[(1r)-2-({2-[4-(2,2-difluoro-2-phenylethoxy)phenyl] ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1h)-one.
EP2666465A1 (en) 2012-05-25 2013-11-27 Almirall, S.A. Novel dosage and formulation
EP2668941A1 (en) 2012-05-31 2013-12-04 Almirall, S.A. Novel dosage form and formulation of abediterol
US20150202392A1 (en) * 2012-07-20 2015-07-23 Sanofi Sa Metering element for an inhalation device and inhalation device comprising a metering element
WO2014060431A1 (en) 2012-10-16 2014-04-24 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
EP2738172A1 (en) 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
MA38260B1 (fr) 2012-12-18 2018-04-30 Almirall Sa Nouveaux dérivés de cyclohexyl et quinuclidinyl carbamate ayant une activité d'agoniste adrénergique beta2 et une activité d'antagoniste muscarinique m3
UY35332A (es) 2013-02-15 2014-11-28 Almirall Sa Derivados de pirrolotriazina como inhibidores de pi3k
AR095222A1 (es) * 2013-04-03 2015-09-30 Sanofi Sa Elemento de medición para un dispositivo de inhalación y montaje para un dispositivo de inhalación que comprende un elemento de medición
EP2848615A1 (en) 2013-07-03 2015-03-18 Almirall, S.A. New pyrazole derivatives as CRAC channel modulators
WO2015091285A1 (en) 2013-12-19 2015-06-25 Almirall S.A. Dosage formulation comprising salmeterol and fluticasone propionate
US10610651B2 (en) 2014-06-09 2020-04-07 Aerami Therapeutics, Inc. Self-puncturing liquid drug cartridges and associated dispenser
US10214509B2 (en) 2015-04-21 2019-02-26 Almirall, S.A. Amino-substituted heterocyclic derivatives as sodium channel inhibitors
WO2016202800A1 (en) 2015-06-16 2016-12-22 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
WO2017076990A1 (en) 2015-11-05 2017-05-11 Almirall, S.A. Addition salts of n-[4-(4-{[(1s)-1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-1h-indol-6-yl]sulfamide
TW201919682A (zh) 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 活化Nrf2路徑的新穎化合物
CN109172978B (zh) * 2018-10-17 2024-07-02 河南省人民医院 智能可调式单向排气装置
EP3693044A1 (en) * 2019-02-07 2020-08-12 Koninklijke Philips N.V. Breath actuated inhalers
KR20210117266A (ko) * 2019-01-14 2021-09-28 필립모리스 프로덕츠 에스.에이. 건조 분말 흡입기
WO2024015888A1 (en) * 2022-07-14 2024-01-18 Boston Scientific Scimed, Inc. Valve assembly for a device for delivering agents

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US2829642A (en) * 1954-10-18 1958-04-08 Melfy Frank A De Nebulizer having means for eliminating failures
US2992645A (en) * 1958-05-06 1961-07-18 Benger Lab Ltd Disperser for powders
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
US3900138A (en) * 1972-08-07 1975-08-19 Minnesota Mining & Mfg Medicament dispenser
FR2224175B1 (sk) * 1973-04-04 1978-04-14 Isf Spa
GB1479283A (en) * 1973-07-23 1977-07-13 Bespak Industries Ltd Inhaler for powdered medicament
US4014336A (en) * 1975-01-13 1977-03-29 Syntex Puerto Rico, Inc. Inhalation device
FR2299011A1 (fr) * 1975-01-29 1976-08-27 Obert Jean Claude Generateur d'aerosols de part
SE411705B (sv) * 1976-11-09 1980-02-04 Draco Ab Anordning for generering av en avskermad, vesentligen drivmedelsfri aerosol
DE2726934A1 (de) * 1977-06-15 1979-01-04 Wokoeck Hans Dieter Vorrichtung zur feinverteilten gleichmaessigen bedeckung eines unregelmaessig gestalteten gegenstandes
US4274403A (en) * 1979-08-29 1981-06-23 Struve Roger L Inhaler
DE3040641A1 (de) * 1980-10-29 1982-05-27 C.H. Boehringer Sohn, 6507 Ingelheim Mundrohr fuer dosieraerosol-geraete
SE438261B (sv) * 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
FR2516387A1 (fr) * 1981-11-16 1983-05-20 Fabre Sa Pierre Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication
US4570630A (en) * 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
FI69963C (fi) * 1984-10-04 1986-09-12 Orion Yhtymae Oy Doseringsanordning
US4803978A (en) * 1985-08-09 1989-02-14 Johnson Iv John J Apparatus for actuating an inhaler
FR2598918B1 (fr) * 1986-05-23 1988-08-05 Lille Ii Universite Droit Sant Dispositif permettant l'insufflation dans les voies respiratoires d'une poudre radio-opaque a l'etat finement divise
GB8804069D0 (en) * 1988-02-22 1988-03-23 Britains Petite Ltd Dispensers for powdered medication
EP0363060B1 (en) * 1988-10-04 1994-04-27 The Johns Hopkins University Aerosol inhaler
DK479189D0 (da) * 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.

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AU654499B2 (en) 1994-11-10
HUT66984A (en) 1995-01-30
LV10398A (lv) 1995-02-20
WO1992004068A1 (de) 1992-03-19
RU2098144C1 (ru) 1997-12-10
CZ281264B6 (cs) 1996-07-17
US5617845A (en) 1997-04-08
ZA916741B (en) 1992-05-27
FI105078B (fi) 2000-06-15
AU8339891A (en) 1992-03-30
CA2090227A1 (en) 1992-03-01
JP2505339B2 (ja) 1996-06-05
DE4027391A1 (de) 1992-03-12
HU213661B (en) 1997-09-29
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LT3125B (en) 1994-12-27
KR930702037A (ko) 1993-09-08
NO304353B1 (no) 1998-12-07
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FI930845A (fi) 1993-02-25
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FI930845A0 (fi) 1993-02-25
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ATE116558T1 (de) 1995-01-15
DE59104168D1 (de) 1995-02-16
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NZ239530A (en) 1994-12-22
LV10398B (en) 1996-06-20

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