IL98459A - An injectable medical compound that includes microspheres - Google Patents

An injectable medical compound that includes microspheres

Info

Publication number
IL98459A
IL98459A IL9845991A IL9845991A IL98459A IL 98459 A IL98459 A IL 98459A IL 9845991 A IL9845991 A IL 9845991A IL 9845991 A IL9845991 A IL 9845991A IL 98459 A IL98459 A IL 98459A
Authority
IL
Israel
Prior art keywords
microspheres
injection
active substance
microsphere
progesterone
Prior art date
Application number
IL9845991A
Other languages
English (en)
Hebrew (he)
Other versions
IL98459A0 (en
Original Assignee
Aplicaciones Farmaceuticas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aplicaciones Farmaceuticas filed Critical Aplicaciones Farmaceuticas
Publication of IL98459A0 publication Critical patent/IL98459A0/xx
Publication of IL98459A publication Critical patent/IL98459A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
IL9845991A 1990-06-14 1991-06-11 An injectable medical compound that includes microspheres IL98459A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007416A FR2663223B1 (fr) 1990-06-14 1990-06-14 Forme galenique parenterale.

Publications (2)

Publication Number Publication Date
IL98459A0 IL98459A0 (en) 1992-07-15
IL98459A true IL98459A (en) 1996-09-12

Family

ID=9397598

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9845991A IL98459A (en) 1990-06-14 1991-06-11 An injectable medical compound that includes microspheres

Country Status (30)

Country Link
US (3) US5360616A (es)
EP (1) EP0533739B1 (es)
JP (1) JP2675675B2 (es)
KR (1) KR0157439B1 (es)
CN (1) CN1057442C (es)
AT (1) ATE109658T1 (es)
AU (1) AU661275B2 (es)
BG (1) BG61179B1 (es)
BR (1) BR9106545A (es)
CA (1) CA2085344C (es)
CZ (1) CZ286793B6 (es)
DE (1) DE69103419T2 (es)
DK (1) DK0533739T3 (es)
ES (1) ES2059142T3 (es)
FI (1) FI107698B (es)
FR (1) FR2663223B1 (es)
HU (1) HUT68709A (es)
IE (1) IE62679B1 (es)
IL (1) IL98459A (es)
NO (1) NO302998B1 (es)
NZ (1) NZ238542A (es)
PL (1) PL167234B1 (es)
PT (1) PT97975B (es)
RU (1) RU2104692C1 (es)
SK (1) SK280564B6 (es)
TN (1) TNSN91048A1 (es)
UA (1) UA27043C2 (es)
UY (1) UY23240A1 (es)
WO (1) WO1991019484A1 (es)
ZA (1) ZA914550B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2663224B1 (fr) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa Forme galenique parenterale.
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
FR2732621B1 (fr) * 1995-04-10 1997-06-06 Rhone Poulenc Chimie Perles d'un produit presentant le phenomene de surfusion et leur procede d'obtention
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
US6028057A (en) * 1998-02-19 2000-02-22 Thorn Bioscience, Llc Regulation of estrus and ovulation in gilts
US6287693B1 (en) * 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
CA2321924A1 (en) * 1998-02-25 1999-09-02 Abbott Laboratories Butorphanol sustained release formulations
WO2001013885A1 (en) * 1999-08-20 2001-03-01 Norton Healthcare Ltd. Method to produce powders for pulmonary or nasal administration
US20070254008A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic formulation and method of treatment
US20070254009A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic/bone morphogenic protein formulation and method of treatment
US20030055075A1 (en) * 2001-07-13 2003-03-20 Rubsamen Reid M. Programmable controlled release injectable opioid formulation
GB0117696D0 (en) * 2001-07-20 2001-09-12 Bradford Particle Design Plc Particle information
EP1820494B1 (en) * 2003-06-13 2010-01-13 Skendi Finance, Ltd. Microparticles consisting of estradiol and cholesterol
US20050032811A1 (en) 2003-08-06 2005-02-10 Josiah Brown Methods for administering aripiprazole
SI1660009T1 (sl) 2003-09-03 2015-07-31 Miscon Trading S.A. Metode za zdravljenje endometrioze
EP3025722B1 (en) * 2003-10-03 2020-05-27 Thorn BioScience, LLC Process for the synchronization of ovulation for timed breeding without heat detection
JP4836797B2 (ja) 2003-10-23 2011-12-14 大塚製薬株式会社 放出制御性無菌注射アリピプラゾール製剤および方法
US7413690B1 (en) 2003-10-29 2008-08-19 The University Of Mississippi Process and apparatus for producing spherical pellets using molten solid matrices
US7491263B2 (en) * 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
US7392635B2 (en) * 2005-06-09 2008-07-01 Tipper Tie, Inc. Breech loader packaging systems and associated breech loading chutes and methods
US20070197435A1 (en) * 2006-02-17 2007-08-23 Webel Stephen K Process for the synchronization of ovulation for timed breeding without heat detection
WO2008054725A2 (en) 2006-10-31 2008-05-08 Surmodics Pharmaceuticals, Inc. Spheronized polymer particles
DK2170279T3 (en) 2007-07-31 2018-03-12 Otsuka Pharma Co Ltd PROCEDURES FOR PREPARING AN ARIPIPRAZOL SUSPENSION AND A FREEZER DRIED FORMULATION
CN102056611A (zh) * 2008-04-14 2011-05-11 Posi维森纳里解决方案有限责任公司 用于获得不同的治疗适应症所需要的血浆孕酮水平的方法和药物组合物
PL2421545T3 (pl) 2009-04-23 2018-05-30 Jbs United Animal Health Ii Llc Sposób i kompozycja do synchronizacji czasu inseminacji
UY33103A (es) * 2009-12-15 2011-07-29 Techsphere S A De C V Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico
WO2014085674A1 (en) 2012-11-28 2014-06-05 Jbs United Animal Health Ii Llc Method for synchronizing time of insemination in gilts
WO2017105512A1 (en) 2015-12-18 2017-06-22 Proinvet Innovations S.A. Formulations and methods for controlling the reproductive cycle and ovulation
WO2017147274A1 (en) * 2016-02-24 2017-08-31 Eastern Virginia Medical School An improved formulation of long-acting levonorgestrel butanoate injectable depot suspension
CN106063783B (zh) * 2016-06-16 2019-03-12 浙江爱生药业有限公司 一种黄体酮缓释微囊制剂及其制备方法
US11376220B2 (en) 2017-06-30 2022-07-05 Therio, LLC Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals
CN115212170B (zh) * 2021-04-19 2024-01-26 中国人民解放军军事科学院军事医学研究院 一种致密圆整的药物球形微晶及其制备方法和其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE670438A (es) * 1964-10-06 1966-01-31
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3928566A (en) * 1970-08-14 1975-12-23 Du Pont Lyophilized biological products
JPS5017525A (es) * 1973-06-14 1975-02-24
CA1077842A (en) * 1975-10-09 1980-05-20 Minnesota Mining And Manufacturing Company Albumin medicament carrier system
US4244949A (en) * 1978-04-06 1981-01-13 The Population Council, Inc. Manufacture of long term contraceptive implant
US4349580A (en) * 1978-08-18 1982-09-14 Queen's University At Kingston Process and solution for preserving green plant tissues
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
US4349530A (en) * 1980-12-11 1982-09-14 The Ohio State University Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
IL79407A (en) * 1985-08-01 1991-03-10 Theragenics Corp System and method for delivering insoluble material into a living body
ES2039219T3 (es) * 1986-08-11 1993-09-16 American Cyanamid Company Composiciones para administracion parenteral y su uso.
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use
US4892734A (en) * 1987-04-06 1990-01-09 Endocon, Inc. Dispensing paste for forming medicinal pellets
US4748024A (en) * 1987-04-06 1988-05-31 Endocon, Inc. Flash flow fused medicinal implants
DE3851145T2 (de) * 1987-04-06 1994-12-15 Aberlyn Capital Management Par Durch schnellschmelzen hergestellte medizinische implantate.
US5019400A (en) * 1989-05-01 1991-05-28 Enzytech, Inc. Very low temperature casting of controlled release microspheres
DE69005800T2 (de) * 1989-05-01 1994-05-19 Alkermes Inc Verfahren zur herstellung von kleinen partikeln von biologisch aktiven molekülen.

Also Published As

Publication number Publication date
FI925661A0 (fi) 1992-12-11
ATE109658T1 (de) 1994-08-15
ES2059142T3 (es) 1994-11-01
CS181691A3 (en) 1992-06-17
CA2085344A1 (en) 1991-12-15
PT97975A (pt) 1992-04-30
NO302998B1 (no) 1998-05-18
BG61179B1 (bg) 1997-02-28
US5633014A (en) 1997-05-27
PT97975B (pt) 1998-11-30
FR2663223B1 (fr) 1994-12-02
US5512303A (en) 1996-04-30
AU8084791A (en) 1992-01-07
CN1057961A (zh) 1992-01-22
FI925661A (fi) 1992-12-11
PL167234B1 (pl) 1995-08-31
UY23240A1 (es) 1991-07-12
RU2104692C1 (ru) 1998-02-20
DE69103419D1 (de) 1994-09-15
SK280564B6 (sk) 2000-03-13
CA2085344C (en) 1998-06-30
CZ286793B6 (cs) 2000-07-12
DE69103419T2 (de) 1995-03-30
FI107698B (fi) 2001-09-28
JP2675675B2 (ja) 1997-11-12
NO924792L (no) 1993-02-03
BR9106545A (pt) 1993-06-01
EP0533739B1 (fr) 1994-08-10
WO1991019484A1 (fr) 1991-12-26
UA27043C2 (uk) 2000-02-28
IL98459A0 (en) 1992-07-15
IE62679B1 (en) 1995-02-22
HU9203958D0 (en) 1993-03-29
PL290677A1 (en) 1992-11-30
CN1057442C (zh) 2000-10-18
AU661275B2 (en) 1995-07-20
NO924792D0 (no) 1992-12-11
IE912017A1 (en) 1991-12-18
KR0157439B1 (ko) 1998-11-16
ZA914550B (en) 1992-03-25
HUT68709A (en) 1995-07-28
JPH05507694A (ja) 1993-11-04
NZ238542A (en) 1993-09-27
FR2663223A1 (fr) 1991-12-20
BG97166A (bg) 1993-12-24
TNSN91048A1 (fr) 1992-10-25
EP0533739A1 (fr) 1993-03-31
DK0533739T3 (da) 1995-01-09
US5360616A (en) 1994-11-01

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees