ES2059142T3 - Composicion farmaceutica inyectable. - Google Patents

Composicion farmaceutica inyectable.

Info

Publication number
ES2059142T3
ES2059142T3 ES91910762T ES91910762T ES2059142T3 ES 2059142 T3 ES2059142 T3 ES 2059142T3 ES 91910762 T ES91910762 T ES 91910762T ES 91910762 T ES91910762 T ES 91910762T ES 2059142 T3 ES2059142 T3 ES 2059142T3
Authority
ES
Spain
Prior art keywords
pharmaceutical composition
injectable pharmaceutical
estradiol
steroids
parenteral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91910762T
Other languages
English (en)
Inventor
Garza Flores Josue
Soto Laura P Laiseca
Pichardo Jose Guillen
Uribe Juan Angeles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aplicaciones Farmaceuticas SA de CV
Original Assignee
Aplicaciones Farmaceuticas SA de CV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aplicaciones Farmaceuticas SA de CV filed Critical Aplicaciones Farmaceuticas SA de CV
Application granted granted Critical
Publication of ES2059142T3 publication Critical patent/ES2059142T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

FORMULACIONES DE MEDICAMENTOS DE LIBERACION PROGRAMADA DESTINADAS A LA ADMINISTRACION, PARENTERAL POR INYECCION, QUE COMPRENDEN MICROESFERAS CALIBRADAS SOLIDAS (1 A 300 MICRONES) DE SUSTANCIAS ACTIVAS. PRESENTADAS BAJO ESTA FORMA, UNOS ESTEROIDES (POR EJEMPLO PROGESTERONA Y 17-BETA-ESTRADIOL) PUEDEN CONSTITUIR ANTICONCEPTIVOS INYECTABLES, Y LA ACCION DE MEDICAMENTOS DE DURACION DEL ORDEN DE 24 HORAS PUEDEN SER REGULADA Y PROLONGADA.
ES91910762T 1990-06-14 1991-06-12 Composicion farmaceutica inyectable. Expired - Lifetime ES2059142T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007416A FR2663223B1 (fr) 1990-06-14 1990-06-14 Forme galenique parenterale.

Publications (1)

Publication Number Publication Date
ES2059142T3 true ES2059142T3 (es) 1994-11-01

Family

ID=9397598

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91910762T Expired - Lifetime ES2059142T3 (es) 1990-06-14 1991-06-12 Composicion farmaceutica inyectable.

Country Status (30)

Country Link
US (3) US5360616A (es)
EP (1) EP0533739B1 (es)
JP (1) JP2675675B2 (es)
KR (1) KR0157439B1 (es)
CN (1) CN1057442C (es)
AT (1) ATE109658T1 (es)
AU (1) AU661275B2 (es)
BG (1) BG61179B1 (es)
BR (1) BR9106545A (es)
CA (1) CA2085344C (es)
CZ (1) CZ286793B6 (es)
DE (1) DE69103419T2 (es)
DK (1) DK0533739T3 (es)
ES (1) ES2059142T3 (es)
FI (1) FI107698B (es)
FR (1) FR2663223B1 (es)
HU (1) HUT68709A (es)
IE (1) IE62679B1 (es)
IL (1) IL98459A (es)
NO (1) NO302998B1 (es)
NZ (1) NZ238542A (es)
PL (1) PL167234B1 (es)
PT (1) PT97975B (es)
RU (1) RU2104692C1 (es)
SK (1) SK280564B6 (es)
TN (1) TNSN91048A1 (es)
UA (1) UA27043C2 (es)
UY (1) UY23240A1 (es)
WO (1) WO1991019484A1 (es)
ZA (1) ZA914550B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2663224B1 (fr) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa Forme galenique parenterale.
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
FR2732621B1 (fr) * 1995-04-10 1997-06-06 Rhone Poulenc Chimie Perles d'un produit presentant le phenomene de surfusion et leur procede d'obtention
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
US6028057A (en) * 1998-02-19 2000-02-22 Thorn Bioscience, Llc Regulation of estrus and ovulation in gilts
ATE265846T1 (de) * 1998-02-25 2004-05-15 Abbott Lab Butorphanol enthaltende formulierungen mit verzögerter freisetzung
US6287693B1 (en) 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
CA2382216A1 (en) * 1999-08-20 2001-03-01 Xian Ming Zeng Method to produce powders for pulmonary or nasal administration
US20030055075A1 (en) * 2001-07-13 2003-03-20 Rubsamen Reid M. Programmable controlled release injectable opioid formulation
US20070254008A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic formulation and method of treatment
US20070254009A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic/bone morphogenic protein formulation and method of treatment
GB0117696D0 (en) * 2001-07-20 2001-09-12 Bradford Particle Design Plc Particle information
AU2004246870B2 (en) 2003-06-13 2009-07-23 Skendi Finance Ltd Slow release estradiol-progesterone formulation for contraception and hormone replacement therapy
US20050032811A1 (en) 2003-08-06 2005-02-10 Josiah Brown Methods for administering aripiprazole
US9532995B2 (en) 2003-09-03 2017-01-03 Miscon Trading S.A. Methods for the treatment of endometriosis
US7205281B2 (en) 2003-10-03 2007-04-17 Thorn Bioscience, Llc Process for the synchronization of ovulation for timed breeding without heat detection
BRPI0415531B8 (pt) 2003-10-23 2021-05-25 Otsuka Pharma Co Ltd formulação de aripiprazol injetável estéril de liberação controlada e método para a sua preparação
US7413690B1 (en) 2003-10-29 2008-08-19 The University Of Mississippi Process and apparatus for producing spherical pellets using molten solid matrices
US7491263B2 (en) * 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
US7392635B2 (en) * 2005-06-09 2008-07-01 Tipper Tie, Inc. Breech loader packaging systems and associated breech loading chutes and methods
US20070197435A1 (en) * 2006-02-17 2007-08-23 Webel Stephen K Process for the synchronization of ovulation for timed breeding without heat detection
ATE475686T1 (de) 2006-10-31 2010-08-15 Surmodics Pharmaceuticals Inc Kugelförmige polymer-teilchen
AR067747A1 (es) 2007-07-31 2009-10-21 Otsuka Pharma Co Ltd Metodos para producir suspension de aripiprazol y formulacion liofilizada
CN102056611A (zh) * 2008-04-14 2011-05-11 Posi维森纳里解决方案有限责任公司 用于获得不同的治疗适应症所需要的血浆孕酮水平的方法和药物组合物
WO2010124220A1 (en) 2009-04-23 2010-10-28 Pennatek, Llc Method and composition for synchronizing time of insemination
UY33103A (es) * 2009-12-15 2011-07-29 Techsphere S A De C V Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico
CN113398243A (zh) 2012-11-28 2021-09-17 联合动物健康第二有限责任公司 用于同步小母猪的授精时间的方法
WO2017105512A1 (en) 2015-12-18 2017-06-22 Proinvet Innovations S.A. Formulations and methods for controlling the reproductive cycle and ovulation
CA3015781C (en) * 2016-02-24 2024-04-23 Eastern Virginia Medical School An improved formulation of long-acting levonorgestrel butanoate injectable depot suspension
CN106063783B (zh) * 2016-06-16 2019-03-12 浙江爱生药业有限公司 一种黄体酮缓释微囊制剂及其制备方法
US11376220B2 (en) 2017-06-30 2022-07-05 Therio, LLC Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals
CN115212170B (zh) * 2021-04-19 2024-01-26 中国人民解放军军事科学院军事医学研究院 一种致密圆整的药物球形微晶及其制备方法和其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE670438A (es) * 1964-10-06 1966-01-31
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3928566A (en) * 1970-08-14 1975-12-23 Du Pont Lyophilized biological products
JPS5017525A (es) * 1973-06-14 1975-02-24
CA1077842A (en) * 1975-10-09 1980-05-20 Minnesota Mining And Manufacturing Company Albumin medicament carrier system
US4244949A (en) * 1978-04-06 1981-01-13 The Population Council, Inc. Manufacture of long term contraceptive implant
US4349580A (en) * 1978-08-18 1982-09-14 Queen's University At Kingston Process and solution for preserving green plant tissues
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
US4349530A (en) * 1980-12-11 1982-09-14 The Ohio State University Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
IL79407A (en) * 1985-08-01 1991-03-10 Theragenics Corp System and method for delivering insoluble material into a living body
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use
ES2039219T3 (es) * 1986-08-11 1993-09-16 American Cyanamid Company Composiciones para administracion parenteral y su uso.
US4892734A (en) * 1987-04-06 1990-01-09 Endocon, Inc. Dispensing paste for forming medicinal pellets
ATE109941T1 (de) * 1987-04-06 1994-09-15 Endocon Inc Durch schnellschmelzen hergestellte medizinische implantate.
US4748024A (en) * 1987-04-06 1988-05-31 Endocon, Inc. Flash flow fused medicinal implants
CA2030551C (en) * 1989-05-01 1998-08-25 Wayne Gombotz Process for producing small particles of biologically active molecules
US5019400A (en) * 1989-05-01 1991-05-28 Enzytech, Inc. Very low temperature casting of controlled release microspheres

Also Published As

Publication number Publication date
CS181691A3 (en) 1992-06-17
DE69103419D1 (de) 1994-09-15
US5633014A (en) 1997-05-27
FI925661A (fi) 1992-12-11
NO924792L (no) 1993-02-03
ATE109658T1 (de) 1994-08-15
EP0533739A1 (fr) 1993-03-31
IL98459A0 (en) 1992-07-15
HUT68709A (en) 1995-07-28
RU2104692C1 (ru) 1998-02-20
BG61179B1 (bg) 1997-02-28
PL167234B1 (pl) 1995-08-31
DE69103419T2 (de) 1995-03-30
PT97975A (pt) 1992-04-30
CZ286793B6 (cs) 2000-07-12
UA27043C2 (uk) 2000-02-28
FI107698B (fi) 2001-09-28
NZ238542A (en) 1993-09-27
TNSN91048A1 (fr) 1992-10-25
WO1991019484A1 (fr) 1991-12-26
FR2663223B1 (fr) 1994-12-02
DK0533739T3 (da) 1995-01-09
CA2085344A1 (en) 1991-12-15
NO302998B1 (no) 1998-05-18
FI925661A0 (fi) 1992-12-11
PL290677A1 (en) 1992-11-30
CN1057442C (zh) 2000-10-18
UY23240A1 (es) 1991-07-12
ZA914550B (en) 1992-03-25
HU9203958D0 (en) 1993-03-29
PT97975B (pt) 1998-11-30
EP0533739B1 (fr) 1994-08-10
CN1057961A (zh) 1992-01-22
AU8084791A (en) 1992-01-07
IE912017A1 (en) 1991-12-18
NO924792D0 (no) 1992-12-11
KR0157439B1 (ko) 1998-11-16
CA2085344C (en) 1998-06-30
BR9106545A (pt) 1993-06-01
US5512303A (en) 1996-04-30
JPH05507694A (ja) 1993-11-04
SK280564B6 (sk) 2000-03-13
AU661275B2 (en) 1995-07-20
JP2675675B2 (ja) 1997-11-12
FR2663223A1 (fr) 1991-12-20
BG97166A (bg) 1993-12-24
IE62679B1 (en) 1995-02-22
US5360616A (en) 1994-11-01
IL98459A (en) 1996-09-12

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