ATE212840T1 - Oral anzuwendende feste arzneizubereitungen mit modulierter wirkstoffabgabe enthaltend nicorandil und verfahren zu deren herstellung - Google Patents

Oral anzuwendende feste arzneizubereitungen mit modulierter wirkstoffabgabe enthaltend nicorandil und verfahren zu deren herstellung

Info

Publication number
ATE212840T1
ATE212840T1 AT98935235T AT98935235T ATE212840T1 AT E212840 T1 ATE212840 T1 AT E212840T1 AT 98935235 T AT98935235 T AT 98935235T AT 98935235 T AT98935235 T AT 98935235T AT E212840 T1 ATE212840 T1 AT E212840T1
Authority
AT
Austria
Prior art keywords
production
active ingredients
oral application
medicinal preparations
modulated release
Prior art date
Application number
AT98935235T
Other languages
English (en)
Inventor
Giampaolo Saccucci
Daniele Giovannone
Fabio Carli
Original Assignee
Foscama Biomed Chim Farma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foscama Biomed Chim Farma filed Critical Foscama Biomed Chim Farma
Application granted granted Critical
Publication of ATE212840T1 publication Critical patent/ATE212840T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT98935235T 1997-08-08 1998-08-06 Oral anzuwendende feste arzneizubereitungen mit modulierter wirkstoffabgabe enthaltend nicorandil und verfahren zu deren herstellung ATE212840T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI001913A IT1293835B1 (it) 1997-08-08 1997-08-08 Composizioni farmaceutiche orali in forma solida a cessione modulata contenenti nicorandil e procedimento per la loro preparazione
PCT/IB1998/001207 WO1999007370A1 (en) 1997-08-08 1998-08-06 Oral solid pharmaceutical compositions containing nicorandil for a modulated release and the process for their preparation

Publications (1)

Publication Number Publication Date
ATE212840T1 true ATE212840T1 (de) 2002-02-15

Family

ID=11377749

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98935235T ATE212840T1 (de) 1997-08-08 1998-08-06 Oral anzuwendende feste arzneizubereitungen mit modulierter wirkstoffabgabe enthaltend nicorandil und verfahren zu deren herstellung

Country Status (6)

Country Link
EP (1) EP1001773B1 (de)
AT (1) ATE212840T1 (de)
DE (2) DE69803772D1 (de)
ES (1) ES2172172T3 (de)
IT (1) IT1293835B1 (de)
WO (1) WO1999007370A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417207B1 (en) 1999-05-12 2002-07-09 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
PL2098249T3 (pl) 2008-03-05 2013-03-29 Rivopharm Sa Nośniki o zwiększonej trwałości dla nikorandylu
CN114732792A (zh) * 2022-03-25 2022-07-12 北京诺康达医药科技股份有限公司 一种尼可地尔口腔崩解片及其制备方法
CN115317456A (zh) * 2022-08-17 2022-11-11 北京科源创欣科技有限公司 一种尼可地尔片组合物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
JPH0653658B2 (ja) * 1984-12-17 1994-07-20 中外製薬株式会社 安定な錠剤の製造法
KR940000232B1 (ko) * 1986-01-17 1994-01-12 쥬우가이세이야꾸 가부시끼가이샤 니코란딜 제제의 안정화 방법
JPS6351326A (ja) * 1986-08-22 1988-03-04 Nisshin Flour Milling Co Ltd ニコランジル外用剤
IT1256386B (it) * 1992-11-13 1995-12-04 Luigi Boltri Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo
JPH07228531A (ja) * 1994-02-17 1995-08-29 Toyo Capsule Kk ニコランジルカプセル剤
GB2290965A (en) * 1994-07-11 1996-01-17 Therapicon Srl Multiple layer capsules for drugs
JPH08175996A (ja) * 1994-12-22 1996-07-09 Taiyo Yakuhin Kogyo Kk ニコランジル安定化固形製剤の製法
JPH10203935A (ja) * 1996-11-22 1998-08-04 Sansho Seiyaku Co Ltd 育毛剤

Also Published As

Publication number Publication date
IT1293835B1 (it) 1999-03-10
DE69803772T4 (de) 2003-08-28
EP1001773B1 (de) 2002-02-06
ES2172172T3 (es) 2002-09-16
DE69803772D1 (de) 2002-03-21
DE69803772T2 (de) 2002-09-12
EP1001773A1 (de) 2000-05-24
ITMI971913A1 (it) 1999-02-08
WO1999007370A1 (en) 1999-02-18

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties