ES8702140A1 - Un procedimiento para la preparacion de una composicion de etoposido en forma de dosis unitaria para administracion oral - Google Patents

Un procedimiento para la preparacion de una composicion de etoposido en forma de dosis unitaria para administracion oral

Info

Publication number
ES8702140A1
ES8702140A1 ES541370A ES541370A ES8702140A1 ES 8702140 A1 ES8702140 A1 ES 8702140A1 ES 541370 A ES541370 A ES 541370A ES 541370 A ES541370 A ES 541370A ES 8702140 A1 ES8702140 A1 ES 8702140A1
Authority
ES
Spain
Prior art keywords
etoposide
capsules
acid
administered
ethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541370A
Other languages
English (en)
Other versions
ES541370A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES541370A0 publication Critical patent/ES541370A0/es
Publication of ES8702140A1 publication Critical patent/ES8702140A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION DE ETOPOSIDO EN FORMA DE DOSIS UNITARIA PARA ADMINISTRACION ORAL. SE COMBINA POLIETILENGLICOL Y ACIDO TAUROCOLICO PARA FORMAR UNA SUSPENSION, SE INCORPORA A ESTA SUFICIENTE AGUA, ALCOHOL Y UN ACIDO HIDROSOLUBLE PARA FORMAR UNA SOLUCION, SE CALIENTE ESTA A UNOS 65JC, SE ENFRIA HASTA UNOS 35JC, SE DISUELVE EL ETOPOSIDO EN ESTA SOLUCION A UNA TEMPERATURA DE 30 A 35JC, Y SE RELLENAN CAPSULAS DE GELATINA BLANDA CON ESTA SOLUCION TENER 100 MG DE ETOPOSIDO POR CAPSULA. EL PROCEDIMIENTO ES APLICABLE PARA FACILITAR LA ABSORCION DE LOS MEDICAMENTOS.
ES541370A 1984-03-19 1985-03-18 Un procedimiento para la preparacion de una composicion de etoposido en forma de dosis unitaria para administracion oral Expired ES8702140A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59114484A 1984-03-19 1984-03-19

Publications (2)

Publication Number Publication Date
ES541370A0 ES541370A0 (es) 1986-12-16
ES8702140A1 true ES8702140A1 (es) 1986-12-16

Family

ID=24365235

Family Applications (1)

Application Number Title Priority Date Filing Date
ES541370A Expired ES8702140A1 (es) 1984-03-19 1985-03-18 Un procedimiento para la preparacion de una composicion de etoposido en forma de dosis unitaria para administracion oral

Country Status (28)

Country Link
JP (1) JPS60209516A (es)
KR (1) KR850006136A (es)
AT (1) AT392904B (es)
AU (1) AU571308B2 (es)
BE (1) BE901963A (es)
CA (1) CA1238578A (es)
CH (1) CH662731A5 (es)
DE (1) DE3509741A1 (es)
DK (1) DK164535C (es)
EG (1) EG17521A (es)
ES (1) ES8702140A1 (es)
FI (1) FI84023C (es)
FR (1) FR2561104B1 (es)
GB (1) GB2155789B (es)
GR (1) GR850688B (es)
IE (1) IE58340B1 (es)
IL (1) IL74615A (es)
IT (1) IT1187640B (es)
LU (1) LU85812A1 (es)
MY (1) MY101916A (es)
NL (1) NL8500739A (es)
NO (1) NO170569C (es)
NZ (1) NZ211078A (es)
OA (1) OA07968A (es)
PT (1) PT80131B (es)
SE (1) SE8501312L (es)
YU (1) YU45243B (es)
ZA (1) ZA851935B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60239418A (ja) * 1984-05-15 1985-11-28 Nippon Kayaku Co Ltd エトポシド軟カプセル製剤
JPS61189230A (ja) * 1985-02-19 1986-08-22 Nippon Kayaku Co Ltd エトポシド製剤
DE3629386A1 (de) * 1986-08-29 1988-03-03 Scherer Gmbh R P Gelatinekapseln und verfahren zu ihrer herstellung
US4927638A (en) * 1986-10-08 1990-05-22 Bristol-Myers Company Etoposide solutions
US5154930A (en) * 1987-03-05 1992-10-13 The Liposome Company, Inc. Pharmacological agent-lipid solution preparation
US5376381A (en) * 1988-02-25 1994-12-27 The Liposome Company, Inc. Integrity protected gelatin
JP2000247911A (ja) * 1999-02-26 2000-09-12 Hisamitsu Pharmaceut Co Inc 大腸用吸収促進剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH580255A5 (es) * 1974-06-04 1976-09-30 Calinter Sa
DE2452785A1 (de) * 1974-11-07 1976-05-13 Universal Oil Prod Co Verfahren zum betrieb einer verbrennungsmaschine
FR2358144A1 (fr) * 1976-07-13 1978-02-10 Lipha Nouvelle composition medicamenteuse pour le traitement de la lithiase biliaire
JPS5940137B2 (ja) * 1976-10-14 1984-09-28 武田薬品工業株式会社 経口投与用医薬組成物
FR2410504A1 (fr) * 1977-12-05 1979-06-29 Air Liquide Procede de reglage de securite d'un reacteur chimique et installation de reaction d'oxydation mettant en oeuvre ce procede
DE2809543A1 (de) * 1978-03-06 1979-09-13 Werner Henke Verfahren und vorrichtung zum neutralisieren von gasen bei oel- und gasbohrungen
JPS60239418A (ja) * 1984-05-15 1985-11-28 Nippon Kayaku Co Ltd エトポシド軟カプセル製剤

Also Published As

Publication number Publication date
DK122285A (da) 1985-09-20
PT80131A (en) 1985-04-01
DK122285D0 (da) 1985-03-18
FR2561104B1 (fr) 1988-04-08
IL74615A (en) 1988-07-31
NZ211078A (en) 1987-08-31
NO851022L (no) 1985-09-20
AU571308B2 (en) 1988-04-14
AT392904B (de) 1991-07-10
IE850686L (en) 1985-09-19
CA1238578A (en) 1988-06-28
NO170569C (no) 1992-11-04
ZA851935B (en) 1985-10-30
DK164535B (da) 1992-07-13
KR850006136A (ko) 1985-10-02
GB2155789B (en) 1987-10-21
BE901963A (fr) 1985-09-18
SE8501312D0 (sv) 1985-03-18
IL74615A0 (en) 1985-06-30
YU42085A (en) 1988-02-29
ES541370A0 (es) 1986-12-16
IT8519897A0 (it) 1985-03-14
PT80131B (pt) 1987-10-20
SE8501312L (sv) 1985-09-20
CH662731A5 (de) 1987-10-30
GR850688B (es) 1985-07-08
AU3897585A (en) 1985-09-26
NL8500739A (nl) 1985-10-16
FI84023B (fi) 1991-06-28
EG17521A (en) 1990-06-30
GB2155789A (en) 1985-10-02
MY101916A (en) 1992-02-15
GB8506943D0 (en) 1985-04-24
FI851040A0 (fi) 1985-03-15
NO170569B (no) 1992-07-27
ATA81985A (de) 1990-12-15
LU85812A1 (fr) 1985-12-12
FR2561104A1 (fr) 1985-09-20
FI84023C (fi) 1991-10-10
DE3509741A1 (de) 1985-09-26
IT1187640B (it) 1987-12-23
FI851040L (fi) 1985-09-20
JPS60209516A (ja) 1985-10-22
IE58340B1 (en) 1993-09-08
YU45243B (en) 1992-05-28
OA07968A (fr) 1987-01-31
DK164535C (da) 1992-11-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519