ES8707529A1 - Procedimiento para preparar compuestos de imidazo-isoquinoleina y de imidazo-tienopiridina - Google Patents

Procedimiento para preparar compuestos de imidazo-isoquinoleina y de imidazo-tienopiridina

Info

Publication number
ES8707529A1
ES8707529A1 ES553140A ES553140A ES8707529A1 ES 8707529 A1 ES8707529 A1 ES 8707529A1 ES 553140 A ES553140 A ES 553140A ES 553140 A ES553140 A ES 553140A ES 8707529 A1 ES8707529 A1 ES 8707529A1
Authority
ES
Spain
Prior art keywords
imidazo
isoquinoline
preparation
medicaments containing
thienopyridine compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES553140A
Other languages
English (en)
Other versions
ES553140A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19853510044 external-priority patent/DE3510044A1/de
Priority claimed from DE19853546244 external-priority patent/DE3546244A1/de
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES553140A0 publication Critical patent/ES553140A0/es
Publication of ES8707529A1 publication Critical patent/ES8707529A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Abstract

METODO DE PREPARAR COMPUESTOS DE IMIDAZO-ISOQUINOLEINA Y DE IMIDAZO-TIENOPIRIDINA. CONSISTE EN CICLIZAR, EN PRESENCIA DE UN AGENTE CONDENSANTE APROPIADO, UN COMPUESTO DE FORMULA (II), Y EN CASO DADO UNA BASE ASI OBTENIDA SE TRANSFORMA EN UNA SAL POR ADICION DE ACIDO FISIOLOGICAMENTE INOCUA, PARA OBTENER COMPUESTOS IMIDAZO-ISOQUINOLEINA E IMIDAZO-TIENOPIRIDINA DE FORMULA (I), DONDE A ES UN GRUPO, QUE JUNTAMENTE CON LOS DOS ATOMOS DE CARBONO DEL SISTEMA PIRIDILO, FORMA UN GRUPO BENZO SUSTITUIDO; R5 ES UN GRUPO ALQUILO CON C 1 A 4; Y R ES OH, UN GRUPO ALCOXI DE C 1 A 5 SATURADO O INSATURADO, RAMIFICADO O NO RAMIFICADO Y OTROS. TIENEN APLICACIONES FARMACEUTICAS COMO AGENTES DILATADORES DE LOS BRONQUIOS.
ES553140A 1985-03-20 1986-03-19 Procedimiento para preparar compuestos de imidazo-isoquinoleina y de imidazo-tienopiridina Expired ES8707529A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853510044 DE3510044A1 (de) 1985-03-20 1985-03-20 Neue 4-dihydroisochinolinyl- bzw. 4-thieno-dihydropyridinyl-5-amino-oxazole und deren saeureadditionssalze, verfahren zu ihrer herstellung und verwendung
DE19853546244 DE3546244A1 (de) 1985-12-28 1985-12-28 Imidazo-isochinoline und imidazo-thienopyridin-verbindungen, arzneimittel enthaltend diese verbindungen und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ES553140A0 ES553140A0 (es) 1987-08-01
ES8707529A1 true ES8707529A1 (es) 1987-08-01

Family

ID=25830540

Family Applications (2)

Application Number Title Priority Date Filing Date
ES553140A Expired ES8707529A1 (es) 1985-03-20 1986-03-19 Procedimiento para preparar compuestos de imidazo-isoquinoleina y de imidazo-tienopiridina
ES557264A Expired ES8705888A1 (es) 1985-03-20 1986-12-17 Procedimiento para preparar compuetos de imidazo-isoquino-leina y de imidazo-tienopiridina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES557264A Expired ES8705888A1 (es) 1985-03-20 1986-12-17 Procedimiento para preparar compuetos de imidazo-isoquino-leina y de imidazo-tienopiridina

Country Status (15)

Country Link
EP (1) EP0198227A3 (es)
KR (1) KR860007256A (es)
AU (1) AU592551B2 (es)
CA (1) CA1262545A (es)
DK (1) DK127186A (es)
ES (2) ES8707529A1 (es)
FI (1) FI83315C (es)
GR (1) GR860743B (es)
HU (1) HU203751B (es)
IL (1) IL78186A (es)
NO (1) NO163405C (es)
NZ (1) NZ215528A (es)
PT (1) PT82228B (es)
SU (1) SU1456016A3 (es)
YU (1) YU44284B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86131A0 (en) * 1987-04-24 1988-11-15 Boehringer Ingelheim Kg Benzo-and thieno-3,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917610A (en) * 1972-06-30 1975-11-04 Chinoin Gyogyszer Es Vegyeszet Amino-imidazo and amino-pyrazolo-isoquinolines and process for the preparation thereof
HU176214B (en) * 1977-05-18 1981-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new 5,6-dihydro-imidazo-square bracket-5,1-a-square bracket closed-isoquinolin derivatives

Also Published As

Publication number Publication date
ES553140A0 (es) 1987-08-01
EP0198227A2 (de) 1986-10-22
CA1262545A (en) 1989-10-31
FI83315B (fi) 1991-03-15
NO163405B (no) 1990-02-12
YU44284B (en) 1990-04-30
YU43586A (en) 1988-02-29
IL78186A0 (en) 1986-07-31
HUT40657A (en) 1987-01-28
PT82228A (en) 1986-04-01
PT82228B (pt) 1988-07-29
FI861115A (fi) 1986-09-21
NO163405C (no) 1990-05-23
SU1456016A3 (ru) 1989-01-30
ES557264A0 (es) 1987-05-16
AU592551B2 (en) 1990-01-18
FI861115A0 (fi) 1986-03-18
ES8705888A1 (es) 1987-05-16
GR860743B (en) 1986-07-21
IL78186A (en) 1989-09-10
EP0198227A3 (de) 1988-01-13
KR860007256A (ko) 1986-10-10
HU203751B (en) 1991-09-30
NO861083L (no) 1986-09-22
DK127186D0 (da) 1986-03-19
FI83315C (fi) 1991-06-25
NZ215528A (en) 1989-10-27
DK127186A (da) 1986-09-21
AU5495386A (en) 1986-09-25

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506