ES8704484A1 - Procedimiento para preparar 5(4h)-isoxazolonas - Google Patents
Procedimiento para preparar 5(4h)-isoxazolonasInfo
- Publication number
- ES8704484A1 ES8704484A1 ES554312A ES554312A ES8704484A1 ES 8704484 A1 ES8704484 A1 ES 8704484A1 ES 554312 A ES554312 A ES 554312A ES 554312 A ES554312 A ES 554312A ES 8704484 A1 ES8704484 A1 ES 8704484A1
- Authority
- ES
- Spain
- Prior art keywords
- aryl
- preparation
- isoxazolines
- medicaments containing
- aminoalkylidene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEIDMIENTO PARA LA OBTENCION DE 5(4H)-ISOXAZOLONAS DE FORMULA (I), Y DE SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES. COMPRENDE LA REACCION DE UNA AMINA DCE FORMULA HNR3R4 CON UN COMPUESTO DE FORMULA (II) Y 1,3,5-TRIAZINA, PARA FORMAR UN COMPUESTO DE FORMULA (I), EN LA QUE R1-R4 PUEDE SER VARIOS TIPOS DE RADICALES Y Z VALE 1-3. TAMBIEN SE PUEDE HACER REACCIONAR EL COMPUESTO DE FORMULA (III), DONDE X ES UNO DE VARIOS RADICALES CON LA MISMA AMINA; O ESTA AMINA Y EL COMPUESTO DE FORMULA (II) CON EL ORTOESTER DE FORMULA R2C(OR10)3, SIENDO R10 METILO O ETILO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE DISFUNCIONES COGNITIVAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19853515093 DE3515093A1 (de) | 1985-04-26 | 1985-04-26 | 4-aminoalkylidensubstituierte 3-aryl-5(4h)-isoxazolone, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8704484A1 true ES8704484A1 (es) | 1987-04-01 |
ES554312A0 ES554312A0 (es) | 1987-04-01 |
Family
ID=6269184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES554312A Expired ES8704484A1 (es) | 1985-04-26 | 1986-04-24 | Procedimiento para preparar 5(4h)-isoxazolonas |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0199323A3 (es) |
JP (1) | JPS61251674A (es) |
KR (1) | KR860008171A (es) |
AU (1) | AU5671486A (es) |
DE (1) | DE3515093A1 (es) |
DK (1) | DK189786A (es) |
ES (1) | ES8704484A1 (es) |
FI (1) | FI861729A (es) |
GR (1) | GR861100B (es) |
HU (1) | HU194193B (es) |
IL (1) | IL78616A0 (es) |
PT (1) | PT82454B (es) |
ZA (1) | ZA863112B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0367393A3 (en) * | 1988-10-31 | 1991-03-27 | Takeda Chemical Industries, Ltd. | New heterocyclic compounds, production and use thereof |
DK0532725T3 (da) * | 1991-03-28 | 1997-06-02 | Givaudan Roure Int | Isoxazolderivater som lysfilterpræparater |
GB2274282B (en) * | 1993-01-19 | 1996-08-14 | Erba Carlo Spa | Piperazine-and piperidine-isoxazole derivatives |
-
1985
- 1985-04-26 DE DE19853515093 patent/DE3515093A1/de not_active Withdrawn
-
1986
- 1986-04-21 EP EP86105468A patent/EP0199323A3/de not_active Withdrawn
- 1986-04-24 AU AU56714/86A patent/AU5671486A/en not_active Abandoned
- 1986-04-24 ES ES554312A patent/ES8704484A1/es not_active Expired
- 1986-04-24 PT PT82454A patent/PT82454B/pt unknown
- 1986-04-24 FI FI861729A patent/FI861729A/fi not_active Application Discontinuation
- 1986-04-24 HU HU861710A patent/HU194193B/hu unknown
- 1986-04-24 DK DK189786A patent/DK189786A/da not_active Application Discontinuation
- 1986-04-25 GR GR861100A patent/GR861100B/el unknown
- 1986-04-25 IL IL78616A patent/IL78616A0/xx unknown
- 1986-04-25 KR KR1019860003198A patent/KR860008171A/ko not_active Application Discontinuation
- 1986-04-25 JP JP61094974A patent/JPS61251674A/ja active Pending
- 1986-04-25 ZA ZA863112A patent/ZA863112B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PT82454A (de) | 1986-05-01 |
EP0199323A3 (de) | 1987-10-28 |
DK189786D0 (da) | 1986-04-24 |
ZA863112B (en) | 1987-06-24 |
EP0199323A2 (de) | 1986-10-29 |
KR860008171A (ko) | 1986-11-12 |
FI861729A (fi) | 1986-10-27 |
ES554312A0 (es) | 1987-04-01 |
PT82454B (de) | 1988-04-29 |
IL78616A0 (en) | 1986-08-31 |
HUT41749A (en) | 1987-05-28 |
HU194193B (en) | 1988-01-28 |
FI861729A0 (fi) | 1986-04-24 |
AU5671486A (en) | 1986-10-30 |
DK189786A (da) | 1986-10-27 |
GR861100B (en) | 1986-08-19 |
JPS61251674A (ja) | 1986-11-08 |
DE3515093A1 (de) | 1986-10-30 |
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