ES8107189A1 - Procedimiento para la preparacion de sulfonilureas - Google Patents
Procedimiento para la preparacion de sulfonilureasInfo
- Publication number
- ES8107189A1 ES8107189A1 ES497101A ES497101A ES8107189A1 ES 8107189 A1 ES8107189 A1 ES 8107189A1 ES 497101 A ES497101 A ES 497101A ES 497101 A ES497101 A ES 497101A ES 8107189 A1 ES8107189 A1 ES 8107189A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical compositions
- compounds
- processes
- preparation
- compositions based
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE SULFONILUREAS DE FORMULA (I) Y SUS SALES FISIOLOGICAMENTE COMPATIBLES, EN LA QUE N VALE 1 O 2, Y ES ALCOHILENO C2-3 Y R Y R1 PUEDEN SER VARIOS TIPOS DE RADICALES. LA REACCION DE SINTESIS SE LLEVA A CABO POR METODOS CONOCIDOS QUE DEPENDEN DE LOS COMPUESTOS DE PARTIDA UTILIZADOS. SE HACE REACCIONAR UNA AMINA DE FORMULA R1NH2, O SUS SALES, CON DERIVADOS BENCENOSULFONILICOS DE ISOCIANATOS, ESTERES Y TIOLESTERES DE ACIDOS CARBAMICOS, UREAS, SEMICARBACIDAS O SEMICARBAZONAS, SUSTITUIDAS EN POSICION 4 CON EL RADICAL DE FORMULA (II); O SE HACEN REACCIONAR SULFONAMIDAS DE FORMULA (III), O SUS SALES, CON ISOCIANATOS, O ESTERES, TIOLESTERES O HALUROS DE ACIDOS CARBAMICOS O CON UREAS, SUSTITUIDAS CON EL RADICAL R1. TAMBIEN SE PUEDEN OBTENER LAS SULFONILUREAS POR DESDOBLAMIENTO, SUSTITUCION DE AZUFRE POR OXIGENO, OXIDACION O REACCIONES DE CONDENSACION, UTILIZANDO LOS COMPUESTOS DE PARTIDA ADECUADOS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD HIPOGLUCEMICA. *FORMULA*
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792948472 DE2948472A1 (de) | 1979-12-01 | 1979-12-01 | Benzolsulfonylharnstoffe und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES497101A0 ES497101A0 (es) | 1981-10-01 |
| ES8107189A1 true ES8107189A1 (es) | 1981-10-01 |
Family
ID=6087396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES497101A Expired ES8107189A1 (es) | 1979-12-01 | 1980-11-25 | Procedimiento para la preparacion de sulfonilureas |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0029982A1 (es) |
| JP (1) | JPS5690061A (es) |
| DE (1) | DE2948472A1 (es) |
| ES (1) | ES8107189A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2636340B1 (fr) * | 1988-09-09 | 1992-04-17 | Elf France | Procede de preparation de compositions bitume-polymere, application des compositions obtenues a la realisation de revetements et solution mere de polymere utilisable pour l'obtention desdites compositions |
| DE3927369A1 (de) * | 1989-08-19 | 1991-02-21 | Bayer Ag | Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2621958A1 (de) * | 1976-05-18 | 1977-12-08 | Hoechst Ag | Benzolsulfonylharnstoffe und verfahren zu ihrer herstellung |
-
1979
- 1979-12-01 DE DE19792948472 patent/DE2948472A1/de not_active Withdrawn
-
1980
- 1980-11-24 EP EP80107306A patent/EP0029982A1/de not_active Withdrawn
- 1980-11-25 ES ES497101A patent/ES8107189A1/es not_active Expired
- 1980-12-01 JP JP16816680A patent/JPS5690061A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES497101A0 (es) | 1981-10-01 |
| DE2948472A1 (de) | 1981-06-11 |
| JPS5690061A (en) | 1981-07-21 |
| EP0029982A1 (de) | 1981-06-10 |
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