DE3851145T2 - Durch schnellschmelzen hergestellte medizinische implantate. - Google Patents

Durch schnellschmelzen hergestellte medizinische implantate.

Info

Publication number
DE3851145T2
DE3851145T2 DE3851145T DE3851145T DE3851145T2 DE 3851145 T2 DE3851145 T2 DE 3851145T2 DE 3851145 T DE3851145 T DE 3851145T DE 3851145 T DE3851145 T DE 3851145T DE 3851145 T2 DE3851145 T2 DE 3851145T2
Authority
DE
Germany
Prior art keywords
starting materials
clear liquid
melting
quick
heat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3851145T
Other languages
English (en)
Other versions
DE3851145D1 (de
Inventor
Robert J Leonard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aberlyn Capital Management Partnership Waltham M
Original Assignee
ABERLYN CAPITAL MANAGEMENT PARTNERSHIP WALTHAM MASS US
ABERLYN CAPITAL MANAGEMENT PAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/035,379 external-priority patent/US4748024A/en
Priority claimed from US07/175,540 external-priority patent/US4892734A/en
Application filed by ABERLYN CAPITAL MANAGEMENT PARTNERSHIP WALTHAM MASS US, ABERLYN CAPITAL MANAGEMENT PAR filed Critical ABERLYN CAPITAL MANAGEMENT PARTNERSHIP WALTHAM MASS US
Publication of DE3851145D1 publication Critical patent/DE3851145D1/de
Application granted granted Critical
Publication of DE3851145T2 publication Critical patent/DE3851145T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
DE3851145T 1987-04-06 1988-04-04 Durch schnellschmelzen hergestellte medizinische implantate. Expired - Fee Related DE3851145T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/035,379 US4748024A (en) 1987-04-06 1987-04-06 Flash flow fused medicinal implants
US17553388A 1988-03-31 1988-03-31
US07/175,540 US4892734A (en) 1987-04-06 1988-03-31 Dispensing paste for forming medicinal pellets
PCT/US1988/001059 WO1988007816A1 (en) 1987-04-06 1988-04-04 Flash flow fused medicinal implants

Publications (2)

Publication Number Publication Date
DE3851145D1 DE3851145D1 (de) 1994-09-22
DE3851145T2 true DE3851145T2 (de) 1994-12-15

Family

ID=27364836

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3851145T Expired - Fee Related DE3851145T2 (de) 1987-04-06 1988-04-04 Durch schnellschmelzen hergestellte medizinische implantate.

Country Status (5)

Country Link
EP (1) EP0357644B1 (de)
AT (1) ATE109941T1 (de)
DE (1) DE3851145T2 (de)
NO (1) NO178783C (de)
WO (1) WO1988007816A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990010437A1 (en) * 1989-03-09 1990-09-20 Endocon, Inc. Partially fused peptide pellet
FR2663224B1 (fr) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa Forme galenique parenterale.
FR2663223B1 (fr) * 1990-06-14 1994-12-02 Af Aplicaciones Far Lab Forme galenique parenterale.
HU222501B1 (hu) * 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
US5589194A (en) * 1993-09-20 1996-12-31 Minnesota Mining And Manufacturing Company Method of encapsulation and microcapsules produced thereby
US5449679A (en) * 1994-07-29 1995-09-12 Leonard; Robert J. Process and products for reducing biological fluid levels of a lipid soluble waste
US5736152A (en) * 1995-10-27 1998-04-07 Atrix Laboratories, Inc. Non-polymeric sustained release delivery system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4244949A (en) * 1978-04-06 1981-01-13 The Population Council, Inc. Manufacture of long term contraceptive implant
US4349530A (en) * 1980-12-11 1982-09-14 The Ohio State University Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal
DE3273714D1 (en) * 1981-07-31 1986-11-20 Nordtend As Method and means for repelling animals
US4432964A (en) * 1981-08-24 1984-02-21 Alza Corporation Topical composition containing steroid in two forms released independently from polymeric carrier

Also Published As

Publication number Publication date
EP0357644A4 (en) 1991-01-30
DE3851145D1 (de) 1994-09-22
EP0357644A1 (de) 1990-03-14
WO1988007816A1 (en) 1988-10-20
NO178783B (no) 1996-02-26
ATE109941T1 (de) 1994-09-15
NO885376D0 (no) 1988-12-02
NO178783C (no) 1996-06-05
EP0357644B1 (de) 1994-08-17
NO885376L (no) 1989-02-03

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: ABERLYN CAPITAL MANAGEMENT PARTNERSHIP, WALTHAM, M

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee