IL98030A - Separation of the enantiomers of Cimatrol [S] - Cimatrol and its history, their preparation and pharmaceutical preparations containing them - Google Patents

Separation of the enantiomers of Cimatrol [S] - Cimatrol and its history, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL98030A
IL98030A IL9803091A IL9803091A IL98030A IL 98030 A IL98030 A IL 98030A IL 9803091 A IL9803091 A IL 9803091A IL 9803091 A IL9803091 A IL 9803091A IL 98030 A IL98030 A IL 98030A
Authority
IL
Israel
Prior art keywords
acid
compound
tartaric acid
dibenzoyl
cimaterol
Prior art date
Application number
IL9803091A
Other languages
English (en)
Hebrew (he)
Other versions
IL98030A0 (en
Original Assignee
Boehringer Ingelheim Vetmedia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedia filed Critical Boehringer Ingelheim Vetmedia
Publication of IL98030A0 publication Critical patent/IL98030A0/xx
Publication of IL98030A publication Critical patent/IL98030A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Pulmonology (AREA)
  • Food Science & Technology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Birds (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
IL9803091A 1990-05-04 1991-05-02 Separation of the enantiomers of Cimatrol [S] - Cimatrol and its history, their preparation and pharmaceutical preparations containing them IL98030A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4014252A DE4014252A1 (de) 1990-05-04 1990-05-04 Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer

Publications (2)

Publication Number Publication Date
IL98030A0 IL98030A0 (en) 1992-06-21
IL98030A true IL98030A (en) 1995-12-31

Family

ID=6405664

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9803091A IL98030A (en) 1990-05-04 1991-05-02 Separation of the enantiomers of Cimatrol [S] - Cimatrol and its history, their preparation and pharmaceutical preparations containing them

Country Status (27)

Country Link
US (4) US5248695A (id)
EP (2) EP0455155B1 (id)
JP (1) JP2944777B2 (id)
KR (1) KR0183024B1 (id)
AR (1) AR247728A1 (id)
AT (2) ATE124932T1 (id)
AU (1) AU645313B2 (id)
BG (1) BG60743B1 (id)
CA (1) CA2041818C (id)
CZ (1) CZ286389B6 (id)
DE (3) DE4014252A1 (id)
DK (2) DK0589488T3 (id)
ES (2) ES2075255T3 (id)
FI (1) FI109600B (id)
GR (2) GR3017064T3 (id)
HU (1) HU214335B (id)
ID (1) ID966B (id)
IE (2) IE80651B1 (id)
IL (1) IL98030A (id)
NO (1) NO174803B (id)
NZ (1) NZ238032A (id)
PT (1) PT97544B (id)
RU (1) RU2002737C1 (id)
SG (1) SG45439A1 (id)
SK (1) SK279258B6 (id)
TW (1) TW197415B (id)
ZA (1) ZA913337B (id)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4014252A1 (de) * 1990-05-04 1991-11-07 Boehringer Ingelheim Vetmed Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer
GB2289842B (en) * 1991-04-05 1996-01-31 Sepracor Inc Improved use of ß2 bronchodilator drugs
GB9107196D0 (en) * 1991-04-05 1991-05-22 Sandoz Ag Improvements in or relating to organic compounds
AU2247997A (en) * 1996-01-29 1997-08-20 Savor, Evelyn P. Method of treating undesired uterine contractions using optically pure R-or RR-isomers of adrenergic beta-2 agonists
EP1787529A3 (en) * 1997-04-30 2009-11-18 Courage Corporation Pty Ltd. Composition and methods using an eutomer
NZ500250A (en) 1997-04-30 2001-03-30 Bridge Pharma Inc Adrenergic beta-2 agonist eutomers, feed compositions and use for increasing muscle and decreasing fat
ZA994264B (en) 1998-07-01 2000-01-25 Warner Lambert Co Stereoisomers with high affinity for adrenergic receptors.
US7232837B2 (en) 1999-06-29 2007-06-19 Mcneil-Ppc, Inc. Stereoisomers with high affinity for adrenergic receptors
IL152140A0 (en) * 2000-04-27 2003-05-29 Boehringer Ingelheim Pharma Novel, slow-acting betamimetics, a method for their production and their use as medicaments
US20030162459A1 (en) * 2002-02-27 2003-08-28 Osbon Robert Lindsay Method for producing a nonwoven fabric with enhanced characteristics
US20040235922A1 (en) * 2003-05-15 2004-11-25 Baile Clifton A. Compositions and methods for inducing adipose tissue cell death
PL1663197T3 (pl) * 2003-09-09 2008-09-30 Biogen Idec Int Gmbh Zastosowanie pochodnych kwasu fumarowego do leczenia niewydolności serca oraz astmy
SG124283A1 (en) * 2004-03-24 2006-08-30 Trusted Hub Ltd Document signature method & system
ES2348920T3 (es) 2005-04-13 2010-12-17 Astion Development A/S Agonistas de adrenoceptores beta-2 para el tratamiento de enfermedades del tejido conectivo de la piel.
WO2006128180A2 (en) * 2005-05-27 2006-11-30 Children's Medical Center Corporation Methods for the treatment of disease
WO2006138243A2 (en) * 2005-06-13 2006-12-28 University Of Vermont And State Agricultural College Inhibition of creatine uptake to promote weight loss
DK2925725T3 (en) 2012-12-03 2017-01-16 Pfizer androgen receptor modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL136601C (id) * 1967-06-15
US4119710A (en) * 1972-12-18 1978-10-10 Boehringer Ingelheim Gmbh Bronchospasmolytic 1-(p-amino-phenyl)-2-amino-ethanols-(1) and salts
US4407819A (en) * 1980-08-25 1983-10-04 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for the depression of fat deposition in warm blooded animals
US4814350A (en) * 1986-09-10 1989-03-21 American Cyanamid Company Method of treating diabetes with 5-[1-hydroxy-2-(isopropylamino)ethyl]anthranilonitrile
US4792546A (en) * 1986-12-05 1988-12-20 American Cyanamid Company Method for increasing weight gains and reducing deposition of fat in animals
DE4014252A1 (de) * 1990-05-04 1991-11-07 Boehringer Ingelheim Vetmed Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer

Also Published As

Publication number Publication date
KR0183024B1 (ko) 1999-05-15
PT97544B (pt) 1998-08-31
NO174803B (no) 1994-04-05
ZA913337B (en) 1993-01-27
HU214335B (hu) 1998-03-02
GR3025547T3 (en) 1998-03-31
ATE124932T1 (de) 1995-07-15
EP0589488A1 (de) 1994-03-30
KR910019966A (ko) 1991-12-19
NO911746D0 (no) 1991-05-03
DE59108853D1 (de) 1997-10-23
ATE158277T1 (de) 1997-10-15
HU911502D0 (en) 1991-11-28
AU7611191A (en) 1991-11-07
BG60743B1 (bg) 1996-02-29
EP0455155B1 (de) 1995-07-12
DK0589488T3 (da) 1998-05-04
CS129291A3 (en) 1991-11-12
HUT60999A (en) 1992-11-30
PT97544A (pt) 1992-01-31
US5248695A (en) 1993-09-28
NO911746L (no) 1991-11-05
JP2944777B2 (ja) 1999-09-06
IL98030A0 (en) 1992-06-21
ES2075255T3 (es) 1995-10-01
GR3017064T3 (en) 1995-11-30
IE69017B1 (en) 1996-07-24
EP0455155A1 (de) 1991-11-06
CA2041818C (en) 2003-02-11
US5292753A (en) 1994-03-08
AR247728A1 (es) 1995-03-31
CZ286389B6 (cs) 2000-03-15
US5395957A (en) 1995-03-07
ES2109412T3 (es) 1998-01-16
FI912151A (fi) 1991-11-05
US5648386A (en) 1997-07-15
TW197415B (id) 1993-01-01
ID966B (id) 1996-09-30
NO174803C (id) 1994-07-13
JPH04225944A (ja) 1992-08-14
FI109600B (fi) 2002-09-13
IE80651B1 (en) 1998-11-04
FI912151A0 (fi) 1991-05-03
IE911507A1 (en) 1991-11-06
NZ238032A (en) 1996-02-27
SK279258B6 (sk) 1998-08-05
DE4014252A1 (de) 1991-11-07
BG94342A (en) 1994-06-30
AU645313B2 (en) 1994-01-13
CA2041818A1 (en) 1991-11-05
DK0455155T3 (da) 1995-11-13
RU2002737C1 (ru) 1993-11-15
EP0589488B1 (de) 1997-09-17
SG45439A1 (en) 1998-01-16
DE59105957D1 (de) 1995-08-17

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees