IL97607A - 3, 7-Dimethyl-9-) 2, 6, 6- Trimethyl-1-cycloxen-1-yl (-Z (4, 6, 8,) E) 2 (- Non-tetraanoate and pharmaceutical preparations containing it - Google Patents

3, 7-Dimethyl-9-) 2, 6, 6- Trimethyl-1-cycloxen-1-yl (-Z (4, 6, 8,) E) 2 (- Non-tetraanoate and pharmaceutical preparations containing it

Info

Publication number
IL97607A
IL97607A IL9760791A IL9760791A IL97607A IL 97607 A IL97607 A IL 97607A IL 9760791 A IL9760791 A IL 9760791A IL 9760791 A IL9760791 A IL 9760791A IL 97607 A IL97607 A IL 97607A
Authority
IL
Israel
Prior art keywords
compound
cyclohexen
dimethyl
nonatetraenoate
active substance
Prior art date
Application number
IL9760791A
Other languages
English (en)
Hebrew (he)
Other versions
IL97607A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL97607A0 publication Critical patent/IL97607A0/xx
Publication of IL97607A publication Critical patent/IL97607A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Vapour Deposition (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
IL9760791A 1990-03-27 1991-03-20 3, 7-Dimethyl-9-) 2, 6, 6- Trimethyl-1-cycloxen-1-yl (-Z (4, 6, 8,) E) 2 (- Non-tetraanoate and pharmaceutical preparations containing it IL97607A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH100890 1990-03-27

Publications (2)

Publication Number Publication Date
IL97607A0 IL97607A0 (en) 1992-06-21
IL97607A true IL97607A (en) 1996-08-04

Family

ID=4200298

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9760791A IL97607A (en) 1990-03-27 1991-03-20 3, 7-Dimethyl-9-) 2, 6, 6- Trimethyl-1-cycloxen-1-yl (-Z (4, 6, 8,) E) 2 (- Non-tetraanoate and pharmaceutical preparations containing it

Country Status (23)

Country Link
US (1) US5158773A (pt)
EP (1) EP0449099B1 (pt)
JP (1) JPH0798797B2 (pt)
KR (1) KR960008666B1 (pt)
AT (1) ATE130848T1 (pt)
AU (1) AU646439B2 (pt)
CA (1) CA2037150C (pt)
DE (1) DE59106962D1 (pt)
DK (1) DK0449099T3 (pt)
ES (1) ES2080848T3 (pt)
FI (1) FI96201C (pt)
GR (1) GR3019014T3 (pt)
HR (1) HRP930344B1 (pt)
HU (1) HU207980B (pt)
IE (1) IE71178B1 (pt)
IL (1) IL97607A (pt)
MC (1) MC2222A1 (pt)
NO (1) NO174801B (pt)
NZ (1) NZ237513A (pt)
PT (1) PT97148B (pt)
SA (1) SA91110302B1 (pt)
YU (1) YU48480B (pt)
ZA (1) ZA912075B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710176A (en) * 1994-09-16 1998-01-20 Bar-Ilan University Retinoyloxy (substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US6071923A (en) * 1994-09-16 2000-06-06 Bar-Ilan University Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US6040342A (en) * 1994-09-16 2000-03-21 Bar-Ilan University Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US5534261A (en) * 1995-01-17 1996-07-09 University Of Southern California Retinoid-based compositions and method for preventing adhesion formation using the same
WO1998000127A1 (en) * 1996-07-02 1998-01-08 Bar-Ilan University Retinoyloxy(substituted)alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US6130248A (en) * 1996-12-30 2000-10-10 Bar-Ilan University Tricarboxylic acid-containing oxyalkyl esters and uses thereof
US6124495A (en) * 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof
US6110970A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Nitrogen-containing oxyalkylene esters and uses thereof
US6043389A (en) * 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US6110955A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Metabolically stabilized oxyalkylene esters and uses thereof
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
US6030961A (en) * 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
RU2018119510A (ru) 2015-10-30 2019-12-05 Тимбер Фармасьютикалз ЭлЭлСи Композиции изотретиноина и их применение и способы

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476056A (en) * 1982-11-05 1984-10-09 Hoffmann-La Roche Inc. Trifluoromethoxy analogs of aromatic retinoids
US4677120A (en) * 1985-07-31 1987-06-30 Molecular Design International Topical prodrugs for treatment of acne and skin diseases
JP2622955B2 (ja) * 1986-07-29 1997-06-25 エイボン プロダクツ インコ−ポレイテツド 無水化粧品
ZA877325B (en) * 1986-10-06 1988-04-07 F. Hoffmann-La Roche & Co. Aktiengesellschaft Novel retinoids
DK498487A (da) * 1986-10-06 1988-04-07 Hoffmann La Roche Hidtil ukendte retinoider

Also Published As

Publication number Publication date
AU646439B2 (en) 1994-02-24
HU910968D0 (en) 1991-10-28
ATE130848T1 (de) 1995-12-15
SA91110302B1 (ar) 2001-10-07
NO911233L (no) 1991-09-30
FI96201C (fi) 1996-05-27
DK0449099T3 (da) 1996-01-22
YU48480B (sh) 1998-09-18
CA2037150A1 (en) 1991-09-28
HUT57178A (en) 1991-11-28
US5158773A (en) 1992-10-27
FI96201B (fi) 1996-02-15
AU7383191A (en) 1991-10-03
ZA912075B (en) 1991-12-24
GR3019014T3 (en) 1996-05-31
EP0449099A3 (en) 1993-02-03
KR910016674A (ko) 1991-11-05
IE911005A1 (en) 1991-10-09
FI911207A0 (fi) 1991-03-12
PT97148B (pt) 1998-07-31
NO174801C (pt) 1994-07-13
NO911233D0 (no) 1991-03-26
PT97148A (pt) 1991-11-29
NZ237513A (en) 1993-09-27
CA2037150C (en) 1999-12-28
HRP930344A2 (en) 1994-10-31
ES2080848T3 (es) 1996-02-16
FI911207A (fi) 1991-09-28
KR960008666B1 (en) 1996-06-28
JPH04221362A (ja) 1992-08-11
DE59106962D1 (de) 1996-01-11
JPH0798797B2 (ja) 1995-10-25
HU207980B (en) 1993-07-28
EP0449099A2 (de) 1991-10-02
HRP930344B1 (en) 1998-12-31
MC2222A1 (fr) 1993-02-02
IE71178B1 (en) 1997-01-29
NO174801B (no) 1994-04-05
IL97607A0 (en) 1992-06-21
YU45591A (sh) 1994-04-05
EP0449099B1 (de) 1995-11-29

Similar Documents

Publication Publication Date Title
CA2037150C (en) Retinoids
EP0366713B1 (en) Esters of 13-trans-retinoic acid
US4016287A (en) Dermatological compositions containing an acylamino-carboxylic acid or an alkyl ester thereof
US4906617A (en) Pharmaceutical compositions containing saturated aromatic peroxides
US4900478A (en) Novel retinoids
US3836665A (en) Dermatological compositions containing certain higher alkyl esters of 5-pyrrolidone-(2)-carboxylic acid
US10239839B2 (en) Compounds and formulations suitable for radical scavenging
IL44742A (en) Rich in acylamino acids, their preparation and preparations containing them
DE68902772T2 (de) Sulfurierte eicosanoide und deren verwendung in arzneimitteln und kosmetika.
NZ209109A (en) Monohydroxy-benzoyl peroxide and compositions for the treatment of acne
US4654354A (en) Retinoic acid derivatives, process for their preparation and pharmaceutical and cosmetic compositions containing them
EP0290020B1 (fr) Nouveaux rétinoates d'ammonium quaternaires, leur utilisation en cosmétique et en dermopharmacie
DE68915094T2 (de) Benzofuranverbindungen, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische und kosmetische Zusammenstellungen und Verwendung dieser Zusammenstellungen.
EP0365519B1 (en) Topical prodrugs for treatment of acne and skin diseases
DE3523231C2 (de) 1,8-Diacyloxy-10-acylanthrone, Verfahren zu ihrer Herstellung und pharmazeutische und kosmetische Mittel
CA1254517A (fr) Compositions pharmaceutiques contenant comme ingredient actif la dihydroxy-1,8 phenyl-10 anthrone- 9
JPH0761905A (ja) 美白化粧料
FR2540872A1 (fr) Le l-thiazolidine-4 carboxylate de zinc, sa preparation, les compositions topiques le contenant et son utilisation
US5268494A (en) Sulphur-containing eicosanoides and their application in pharmacy and in cosmetics
DE3645312C2 (de) Verwendung von Salicylsäurederivaten in einem topischen kosmetischen oder dermatologischen Mittel mit keratolytischer Wirkung
EP0427625B1 (fr) Nouveaux sels internes des hydroxydes de diamino-2,4 alcoxy-6 sulfooxy-3 pyrimidinium et leur utilisation pour le traitement et la prévention de la chute des cheveux
CA1127655A (en) N-benzoyl-retinylamines, their preparation and pharmaceutical formulations containing these compounds
JP5613776B2 (ja) 新規過酸化物の誘導体、その調製方法、および、ニキビを治療または予防するためのヒト用医薬品および化粧品における使用
DE4033568A1 (de) Bicyclische verbindungen mit antiseborrhoischer wirkung
EP0409729A1 (fr) Thioesters bi-aromatiques, leur procédé de préparation et leur utilisation en médecine humaine ou vétérinaire et en cosmétique

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees