PT97148A - Processo para a prepparacao de novos retinoides e de composicoes farmaceuticas que os contem - Google Patents

Processo para a prepparacao de novos retinoides e de composicoes farmaceuticas que os contem

Info

Publication number
PT97148A
PT97148A PT97148A PT9714891A PT97148A PT 97148 A PT97148 A PT 97148A PT 97148 A PT97148 A PT 97148A PT 9714891 A PT9714891 A PT 9714891A PT 97148 A PT97148 A PT 97148A
Authority
PT
Portugal
Prior art keywords
preparing
contain
pharmaceutical compositions
retinoids
new retinoids
Prior art date
Application number
PT97148A
Other languages
English (en)
Other versions
PT97148B (pt
Inventor
Gunter Gross
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT97148A publication Critical patent/PT97148A/pt
Publication of PT97148B publication Critical patent/PT97148B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
PT97148A 1990-03-27 1991-03-26 Processo para a prepparacao de novos retinoides e de composicoes farmaceuticas que os contem PT97148B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH100890 1990-03-27

Publications (2)

Publication Number Publication Date
PT97148A true PT97148A (pt) 1991-11-29
PT97148B PT97148B (pt) 1998-07-31

Family

ID=4200298

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97148A PT97148B (pt) 1990-03-27 1991-03-26 Processo para a prepparacao de novos retinoides e de composicoes farmaceuticas que os contem

Country Status (23)

Country Link
US (1) US5158773A (pt)
EP (1) EP0449099B1 (pt)
JP (1) JPH0798797B2 (pt)
KR (1) KR960008666B1 (pt)
AT (1) ATE130848T1 (pt)
AU (1) AU646439B2 (pt)
CA (1) CA2037150C (pt)
DE (1) DE59106962D1 (pt)
DK (1) DK0449099T3 (pt)
ES (1) ES2080848T3 (pt)
FI (1) FI96201C (pt)
GR (1) GR3019014T3 (pt)
HR (1) HRP930344B1 (pt)
HU (1) HU207980B (pt)
IE (1) IE71178B1 (pt)
IL (1) IL97607A (pt)
MC (1) MC2222A1 (pt)
NO (1) NO174801B (pt)
NZ (1) NZ237513A (pt)
PT (1) PT97148B (pt)
SA (1) SA91110302B1 (pt)
YU (1) YU48480B (pt)
ZA (1) ZA912075B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071923A (en) * 1994-09-16 2000-06-06 Bar-Ilan University Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US6040342A (en) * 1994-09-16 2000-03-21 Bar-Ilan University Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US5710176A (en) * 1994-09-16 1998-01-20 Bar-Ilan University Retinoyloxy (substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US5534261A (en) * 1995-01-17 1996-07-09 University Of Southern California Retinoid-based compositions and method for preventing adhesion formation using the same
IL127739A0 (en) * 1996-07-02 1999-10-28 Bar Illan University Retinoyloxy (substituted) alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US6130248A (en) * 1996-12-30 2000-10-10 Bar-Ilan University Tricarboxylic acid-containing oxyalkyl esters and uses thereof
US6030961A (en) * 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
US6124495A (en) * 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof
US6110970A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Nitrogen-containing oxyalkylene esters and uses thereof
US6043389A (en) * 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US6110955A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Metabolically stabilized oxyalkylene esters and uses thereof
US6720445B2 (en) * 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
CN113577050A (zh) 2015-10-30 2021-11-02 亭铂医药有限责任公司 异维甲酸制剂及其用途和方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476056A (en) * 1982-11-05 1984-10-09 Hoffmann-La Roche Inc. Trifluoromethoxy analogs of aromatic retinoids
US4677120A (en) * 1985-07-31 1987-06-30 Molecular Design International Topical prodrugs for treatment of acne and skin diseases
JP2622955B2 (ja) * 1986-07-29 1997-06-25 エイボン プロダクツ インコ−ポレイテツド 無水化粧品
DK498487A (da) * 1986-10-06 1988-04-07 Hoffmann La Roche Hidtil ukendte retinoider
ZA877325B (en) * 1986-10-06 1988-04-07 F. Hoffmann-La Roche & Co. Aktiengesellschaft Novel retinoids

Also Published As

Publication number Publication date
PT97148B (pt) 1998-07-31
JPH04221362A (ja) 1992-08-11
NO174801C (pt) 1994-07-13
HU910968D0 (en) 1991-10-28
IE911005A1 (en) 1991-10-09
AU646439B2 (en) 1994-02-24
US5158773A (en) 1992-10-27
FI911207A (fi) 1991-09-28
IL97607A (en) 1996-08-04
KR910016674A (ko) 1991-11-05
NO911233L (no) 1991-09-30
DK0449099T3 (da) 1996-01-22
YU45591A (sh) 1994-04-05
CA2037150C (en) 1999-12-28
KR960008666B1 (en) 1996-06-28
JPH0798797B2 (ja) 1995-10-25
CA2037150A1 (en) 1991-09-28
IE71178B1 (en) 1997-01-29
NZ237513A (en) 1993-09-27
MC2222A1 (fr) 1993-02-02
HU207980B (en) 1993-07-28
NO911233D0 (no) 1991-03-26
YU48480B (sh) 1998-09-18
HUT57178A (en) 1991-11-28
ZA912075B (en) 1991-12-24
ATE130848T1 (de) 1995-12-15
EP0449099A2 (de) 1991-10-02
EP0449099B1 (de) 1995-11-29
FI96201C (fi) 1996-05-27
DE59106962D1 (de) 1996-01-11
IL97607A0 (en) 1992-06-21
HRP930344B1 (en) 1998-12-31
ES2080848T3 (es) 1996-02-16
FI96201B (fi) 1996-02-15
FI911207A0 (fi) 1991-03-12
EP0449099A3 (en) 1993-02-03
GR3019014T3 (en) 1996-05-31
NO174801B (no) 1994-04-05
HRP930344A2 (en) 1994-10-31
AU7383191A (en) 1991-10-03
SA91110302B1 (ar) 2001-10-07

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910724

FG3A Patent granted, date of granting

Effective date: 19980421

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20041021