FI911207A0 - Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi - Google Patents

Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi

Info

Publication number
FI911207A0
FI911207A0 FI911207A FI911207A FI911207A0 FI 911207 A0 FI911207 A0 FI 911207A0 FI 911207 A FI911207 A FI 911207A FI 911207 A FI911207 A FI 911207A FI 911207 A0 FI911207 A0 FI 911207A0
Authority
FI
Finland
Prior art keywords
preparation
therapeutically useful
new therapeutically
useful retinoid
retinoid
Prior art date
Application number
FI911207A
Other languages
English (en)
Swedish (sv)
Other versions
FI911207A (fi
FI96201B (fi
FI96201C (fi
Inventor
Guenter Gross
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI911207A0 publication Critical patent/FI911207A0/fi
Publication of FI911207A publication Critical patent/FI911207A/fi
Publication of FI96201B publication Critical patent/FI96201B/fi
Application granted granted Critical
Publication of FI96201C publication Critical patent/FI96201C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Vapour Deposition (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
FI911207A 1990-03-27 1991-03-12 Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi FI96201C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH100890 1990-03-27
CH100890 1990-03-27

Publications (4)

Publication Number Publication Date
FI911207A0 true FI911207A0 (fi) 1991-03-12
FI911207A FI911207A (fi) 1991-09-28
FI96201B FI96201B (fi) 1996-02-15
FI96201C FI96201C (fi) 1996-05-27

Family

ID=4200298

Family Applications (1)

Application Number Title Priority Date Filing Date
FI911207A FI96201C (fi) 1990-03-27 1991-03-12 Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi

Country Status (23)

Country Link
US (1) US5158773A (fi)
EP (1) EP0449099B1 (fi)
JP (1) JPH0798797B2 (fi)
KR (1) KR960008666B1 (fi)
AT (1) ATE130848T1 (fi)
AU (1) AU646439B2 (fi)
CA (1) CA2037150C (fi)
DE (1) DE59106962D1 (fi)
DK (1) DK0449099T3 (fi)
ES (1) ES2080848T3 (fi)
FI (1) FI96201C (fi)
GR (1) GR3019014T3 (fi)
HR (1) HRP930344B1 (fi)
HU (1) HU207980B (fi)
IE (1) IE71178B1 (fi)
IL (1) IL97607A (fi)
MC (1) MC2222A1 (fi)
NO (1) NO174801B (fi)
NZ (1) NZ237513A (fi)
PT (1) PT97148B (fi)
SA (1) SA91110302B1 (fi)
YU (1) YU48480B (fi)
ZA (1) ZA912075B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710176A (en) * 1994-09-16 1998-01-20 Bar-Ilan University Retinoyloxy (substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US6040342A (en) * 1994-09-16 2000-03-21 Bar-Ilan University Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US6071923A (en) * 1994-09-16 2000-06-06 Bar-Ilan University Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US5534261A (en) * 1995-01-17 1996-07-09 University Of Southern California Retinoid-based compositions and method for preventing adhesion formation using the same
IL127739A0 (en) * 1996-07-02 1999-10-28 Bar Illan University Retinoyloxy (substituted) alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US6130248A (en) * 1996-12-30 2000-10-10 Bar-Ilan University Tricarboxylic acid-containing oxyalkyl esters and uses thereof
US6030961A (en) * 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
US6043389A (en) 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US6110955A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Metabolically stabilized oxyalkylene esters and uses thereof
US6110970A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Nitrogen-containing oxyalkylene esters and uses thereof
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
US6124495A (en) * 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
KR102406880B1 (ko) 2015-10-30 2022-06-08 팀버 파마슈티칼스 엘엘씨 이소트레티노인 제형 및 이의 용도 및 사용 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476056A (en) * 1982-11-05 1984-10-09 Hoffmann-La Roche Inc. Trifluoromethoxy analogs of aromatic retinoids
US4677120A (en) * 1985-07-31 1987-06-30 Molecular Design International Topical prodrugs for treatment of acne and skin diseases
JP2622955B2 (ja) * 1986-07-29 1997-06-25 エイボン プロダクツ インコ−ポレイテツド 無水化粧品
DK498487A (da) * 1986-10-06 1988-04-07 Hoffmann La Roche Hidtil ukendte retinoider
ZA877325B (en) * 1986-10-06 1988-04-07 F. Hoffmann-La Roche & Co. Aktiengesellschaft Novel retinoids

Also Published As

Publication number Publication date
KR960008666B1 (en) 1996-06-28
AU7383191A (en) 1991-10-03
FI911207A (fi) 1991-09-28
ZA912075B (en) 1991-12-24
YU45591A (sh) 1994-04-05
NZ237513A (en) 1993-09-27
HU207980B (en) 1993-07-28
MC2222A1 (fr) 1993-02-02
GR3019014T3 (en) 1996-05-31
IL97607A0 (en) 1992-06-21
DK0449099T3 (da) 1996-01-22
JPH0798797B2 (ja) 1995-10-25
EP0449099B1 (de) 1995-11-29
KR910016674A (ko) 1991-11-05
HUT57178A (en) 1991-11-28
EP0449099A2 (de) 1991-10-02
SA91110302B1 (ar) 2001-10-07
CA2037150A1 (en) 1991-09-28
AU646439B2 (en) 1994-02-24
IE911005A1 (en) 1991-10-09
HRP930344A2 (en) 1994-10-31
EP0449099A3 (en) 1993-02-03
PT97148A (pt) 1991-11-29
HU910968D0 (en) 1991-10-28
IE71178B1 (en) 1997-01-29
DE59106962D1 (de) 1996-01-11
IL97607A (en) 1996-08-04
US5158773A (en) 1992-10-27
ATE130848T1 (de) 1995-12-15
CA2037150C (en) 1999-12-28
FI96201B (fi) 1996-02-15
ES2080848T3 (es) 1996-02-16
YU48480B (sh) 1998-09-18
JPH04221362A (ja) 1992-08-11
PT97148B (pt) 1998-07-31
NO911233D0 (no) 1991-03-26
NO174801C (fi) 1994-07-13
NO911233L (no) 1991-09-30
HRP930344B1 (en) 1998-12-31
NO174801B (no) 1994-04-05
FI96201C (fi) 1996-05-27

Similar Documents

Publication Publication Date Title
CA2083179A1 (en) Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides, pharmaceuticals containing these compounds and their use
FI96204C (fi) Menetelmä terapeuttisesti käyttökelpoisten heterosyklisten yhdisteiden valmistamiseksi
FI911207A0 (fi) Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi
KR960705815A (ko) 신규한 피라진 카복스아미드 유도체, 이의 제조방법 및 약제에 있어서의 이의 용도(Novel pyrazine carboxamide derivatives, their production and their use in medicaments)
FI851637A0 (fi) 1,4-dihydro-4-oxonaftyridinderivat och deras salter, foerfarande foer framstaellning av dessa och dessa omfattande antibakteriella aemnen.
ATE40365T1 (de) 3-acylaminomethylimidazo (1,2-a> pyridine, dessen herstellung und therapeutische anwendung.
NO802843L (no) Fremgangsmaate for fremstilling av aktivt karbon i fibroes form
PT80820B (pt) Processo para a preparacao de derivados de 1,3-propilidenodifosfonato 2-substituidos
NO865275L (no) Fremgangsmaate for kontroll av valsestipp prosess.
PT86314A (de) Zytostatisch wirksame anthracyclinderivate
FI890864A (fi) Anvaendning av 1,4-dihydropyridinderivat.
ES486749A1 (es) Procedimiento para la preparacion de amidas de acidos isoxa-zol-4-carboxilicos
JPS5421509A (en) Drive stop system for motor
IT1141080B (it) L'applicazione in terapuetica come agenti analgesici dei derivati del 4,5,6,7-tetraidroisossazolo (5,4-c)piridin-3-ol
YU42048B (en) Process for obtaining new pyrido (1,2-aopyrimidine derivatives, and optically active and pnysiologically tolerated salts thereof
PT70177A (de) 3,4-dihydroxyzimtaldehydderivat dessen herstellung und arzneimittel
IT7927202A0 (it) Nuove 2-fenilammino-imidazoline-(2)sostitutite, dotate di particolari proprieta' terapeutiche, loro processo di sintesi e composizioni farmaceutiche.
IT1236394B (it) Agente anti psoriasi a base di salicilato di papaverina
SU1095491A1 (ru) Средство дл лечени кардиалгий и легких форм ишемической болезни сердца "мебикар
JPS5362543A (en) Electrochromic display device

Legal Events

Date Code Title Description
BB Publication of examined application
MA Patent expired