MC2222A1 - Nouveaux retinoides - Google Patents

Nouveaux retinoides

Info

Publication number
MC2222A1
MC2222A1 MC912176A MC2176A MC2222A1 MC 2222 A1 MC2222 A1 MC 2222A1 MC 912176 A MC912176 A MC 912176A MC 2176 A MC2176 A MC 2176A MC 2222 A1 MC2222 A1 MC 2222A1
Authority
MC
Monaco
Prior art keywords
signifies
retinoids
alkyl
new retinoids
new
Prior art date
Application number
MC912176A
Other languages
English (en)
French (fr)
Inventor
Gross Guenter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC2222A1 publication Critical patent/MC2222A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Vapour Deposition (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
MC912176A 1990-03-27 1991-03-21 Nouveaux retinoides MC2222A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH100890 1990-03-27

Publications (1)

Publication Number Publication Date
MC2222A1 true MC2222A1 (fr) 1993-02-02

Family

ID=4200298

Family Applications (1)

Application Number Title Priority Date Filing Date
MC912176A MC2222A1 (fr) 1990-03-27 1991-03-21 Nouveaux retinoides

Country Status (23)

Country Link
US (1) US5158773A (xx)
EP (1) EP0449099B1 (xx)
JP (1) JPH0798797B2 (xx)
KR (1) KR960008666B1 (xx)
AT (1) ATE130848T1 (xx)
AU (1) AU646439B2 (xx)
CA (1) CA2037150C (xx)
DE (1) DE59106962D1 (xx)
DK (1) DK0449099T3 (xx)
ES (1) ES2080848T3 (xx)
FI (1) FI96201C (xx)
GR (1) GR3019014T3 (xx)
HR (1) HRP930344B1 (xx)
HU (1) HU207980B (xx)
IE (1) IE71178B1 (xx)
IL (1) IL97607A (xx)
MC (1) MC2222A1 (xx)
NO (1) NO174801B (xx)
NZ (1) NZ237513A (xx)
PT (1) PT97148B (xx)
SA (1) SA91110302B1 (xx)
YU (1) YU48480B (xx)
ZA (1) ZA912075B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710176A (en) * 1994-09-16 1998-01-20 Bar-Ilan University Retinoyloxy (substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US6071923A (en) * 1994-09-16 2000-06-06 Bar-Ilan University Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US6040342A (en) * 1994-09-16 2000-03-21 Bar-Ilan University Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US5534261A (en) * 1995-01-17 1996-07-09 University Of Southern California Retinoid-based compositions and method for preventing adhesion formation using the same
JP2002514161A (ja) * 1996-07-02 2002-05-14 バー イラン ユニバーシティー ガンおよび他の細胞増殖性疾患の治療に有用なレチノイルオキシ（置換）アルキレンブチレート
US6130248A (en) * 1996-12-30 2000-10-10 Bar-Ilan University Tricarboxylic acid-containing oxyalkyl esters and uses thereof
US6043389A (en) 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US6110955A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Metabolically stabilized oxyalkylene esters and uses thereof
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
US6124495A (en) 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof
US6030961A (en) * 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
US6110970A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Nitrogen-containing oxyalkylene esters and uses thereof
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
RU2018119510A (ru) 2015-10-30 2019-12-05 Тимбер Фармасьютикалз ЭлЭлСи Композиции изотретиноина и их применение и способы

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476056A (en) * 1982-11-05 1984-10-09 Hoffmann-La Roche Inc. Trifluoromethoxy analogs of aromatic retinoids
US4677120A (en) * 1985-07-31 1987-06-30 Molecular Design International Topical prodrugs for treatment of acne and skin diseases
JP2622955B2 (ja) * 1986-07-29 1997-06-25 エイボン プロダクツ インコ−ポレイテツド 無水化粧品
ZA877325B (en) * 1986-10-06 1988-04-07 F. Hoffmann-La Roche & Co. Aktiengesellschaft Novel retinoids
DK498487A (da) * 1986-10-06 1988-04-07 Hoffmann La Roche Hidtil ukendte retinoider

Also Published As

Publication number Publication date
IL97607A0 (en) 1992-06-21
IE71178B1 (en) 1997-01-29
FI96201B (fi) 1996-02-15
EP0449099A3 (en) 1993-02-03
YU45591A (sh) 1994-04-05
HRP930344B1 (en) 1998-12-31
AU7383191A (en) 1991-10-03
PT97148A (pt) 1991-11-29
DK0449099T3 (da) 1996-01-22
US5158773A (en) 1992-10-27
FI911207A (fi) 1991-09-28
NO911233L (no) 1991-09-30
FI96201C (fi) 1996-05-27
HU207980B (en) 1993-07-28
IE911005A1 (en) 1991-10-09
KR910016674A (ko) 1991-11-05
PT97148B (pt) 1998-07-31
EP0449099B1 (de) 1995-11-29
NO174801C (xx) 1994-07-13
NO174801B (no) 1994-04-05
NO911233D0 (no) 1991-03-26
JPH0798797B2 (ja) 1995-10-25
JPH04221362A (ja) 1992-08-11
HRP930344A2 (en) 1994-10-31
KR960008666B1 (en) 1996-06-28
EP0449099A2 (de) 1991-10-02
HU910968D0 (en) 1991-10-28
DE59106962D1 (de) 1996-01-11
GR3019014T3 (en) 1996-05-31
YU48480B (sh) 1998-09-18
ES2080848T3 (es) 1996-02-16
NZ237513A (en) 1993-09-27
ATE130848T1 (de) 1995-12-15
CA2037150C (en) 1999-12-28
FI911207A0 (fi) 1991-03-12
CA2037150A1 (en) 1991-09-28
SA91110302B1 (ar) 2001-10-07
IL97607A (en) 1996-08-04
HUT57178A (en) 1991-11-28
ZA912075B (en) 1991-12-24
AU646439B2 (en) 1994-02-24

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