IL95094A - Process for purifying amino methylenephosphonic acids - Google Patents

Process for purifying amino methylenephosphonic acids

Info

Publication number
IL95094A
IL95094A IL9509490A IL9509490A IL95094A IL 95094 A IL95094 A IL 95094A IL 9509490 A IL9509490 A IL 9509490A IL 9509490 A IL9509490 A IL 9509490A IL 95094 A IL95094 A IL 95094A
Authority
IL
Israel
Prior art keywords
solution
temperature
acid
water
edtmp
Prior art date
Application number
IL9509490A
Other languages
English (en)
Other versions
IL95094A0 (en
Inventor
Joseph R Garlich
Jaime Simon
Tipton T Masterson
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Priority to IL11086190A priority Critical patent/IL110861A/xx
Publication of IL95094A0 publication Critical patent/IL95094A0/xx
Publication of IL95094A publication Critical patent/IL95094A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/44—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/025—Purification; Separation; Stabilisation; Desodorisation of organo-phosphorus compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • C07F9/3817—Acids containing the structure (RX)2P(=X)-alk-N...P (X = O, S, Se)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL9509490A 1989-08-04 1990-07-16 Process for purifying amino methylenephosphonic acids IL95094A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL11086190A IL110861A (en) 1989-08-04 1990-07-16 Process for preparing pure ethylediaminetetra (methylenphosphonic acid)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/389,441 US4937333A (en) 1989-08-04 1989-08-04 Method for purifying aminomethylenephosphonic acids for pharmaceutical use

Publications (2)

Publication Number Publication Date
IL95094A0 IL95094A0 (en) 1991-06-10
IL95094A true IL95094A (en) 1995-05-26

Family

ID=23538280

Family Applications (3)

Application Number Title Priority Date Filing Date
IL9509490A IL95094A (en) 1989-08-04 1990-07-16 Process for purifying amino methylenephosphonic acids
IL11086190A IL110861A (en) 1989-08-04 1990-07-16 Process for preparing pure ethylediaminetetra (methylenphosphonic acid)
IL11086194A IL110861A0 (en) 1989-08-04 1994-09-05 Process for preparing pure ethylenediaminetetra (methylenephosphonic acid)

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL11086190A IL110861A (en) 1989-08-04 1990-07-16 Process for preparing pure ethylediaminetetra (methylenphosphonic acid)
IL11086194A IL110861A0 (en) 1989-08-04 1994-09-05 Process for preparing pure ethylenediaminetetra (methylenephosphonic acid)

Country Status (38)

Country Link
US (1) US4937333A (cs)
EP (1) EP0411941B1 (cs)
JP (1) JP2922263B2 (cs)
KR (2) KR0178779B1 (cs)
CN (2) CN1031191C (cs)
AP (1) AP163A (cs)
AT (1) ATE140459T1 (cs)
AU (1) AU634267B2 (cs)
BG (1) BG60519B1 (cs)
BR (2) BR9003694A (cs)
CA (1) CA2020950C (cs)
CZ (1) CZ290556B6 (cs)
DD (1) DD297414A5 (cs)
DE (1) DE69027818T2 (cs)
DK (1) DK0411941T3 (cs)
DZ (1) DZ1436A1 (cs)
EG (1) EG19250A (cs)
ES (1) ES2090105T3 (cs)
FI (1) FI105033B (cs)
GR (1) GR3020932T3 (cs)
HK (1) HK1007558A1 (cs)
HU (1) HU205128B (cs)
IE (1) IE902812A1 (cs)
IL (3) IL95094A (cs)
LV (1) LV10718B (cs)
MA (1) MA21922A1 (cs)
NO (2) NO178196C (cs)
NZ (2) NZ234464A (cs)
OA (1) OA09300A (cs)
PH (1) PH26901A (cs)
PL (2) PL166453B1 (cs)
PT (1) PT94188B (cs)
RO (1) RO105967B1 (cs)
RU (1) RU1838321C (cs)
SA (1) SA90110175B1 (cs)
SK (1) SK379690A3 (cs)
YU (1) YU47368B (cs)
ZA (1) ZA905564B (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937333A (en) * 1989-08-04 1990-06-26 The Dow Chemical Company Method for purifying aminomethylenephosphonic acids for pharmaceutical use
MC2260A1 (fr) * 1990-06-18 1993-04-26 Dow Chemical Co Formulations de produits radiopharmaceutiques,leur methode d'administration et leur procede de preparation
EP0494603A3 (en) * 1991-01-10 1993-10-20 Hoechst Ag Process for extractive separation of phospho- and sulphobetaines from acidic reaction solutions
US5410043A (en) * 1991-12-06 1995-04-25 Schering Aktiengesellschaft Process for the production of mono-N-substituted tetraaza macrocycles
US5320829A (en) * 1991-12-10 1994-06-14 The Dow Chemical Company Oral compositions for inhibiting plaque formation
DE4218744C2 (de) * 1992-06-04 1997-11-06 Schering Ag Verfahren zur Herstellung von N-ß-Hxdroxyalkyl-tri-N-carboxylalkyl-1,4,7,10-tetraazacyclododecan- und N-ß-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivaten und deren Metallkomplexe
US5495042A (en) * 1993-11-04 1996-02-27 Cytogen Corporation Non-alkaline purification of aminophosphonic acids
CA2371728C (en) 1999-06-11 2009-06-02 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) * 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
CA2382877A1 (en) * 1999-10-18 2001-04-26 Dow Global Technologies Inc. Aminoalkylenephosphonates for treatment of bone disorders
US6794371B1 (en) * 1999-10-18 2004-09-21 The Dow Chemical Company Aminoalkylenephosphonates for treatment of bone disorders
JP2002097194A (ja) * 2000-09-20 2002-04-02 Mitsubishi Gas Chem Co Inc 有機ホスホン酸の精製方法
JP2004536034A (ja) 2001-01-08 2004-12-02 ネオルクス コーポレイション 治療的および診断的化合物、組成物および方法
US7550042B2 (en) * 2002-12-27 2009-06-23 Sumitomo Chemical Company Limited Method and apparatus for crystallization
US20060210479A1 (en) * 2004-08-10 2006-09-21 Dow Global Technologies Inc. Targeting chelants and chelates
CN101381377B (zh) * 2008-10-23 2011-05-04 山东省泰和水处理有限公司 一种适用于电子级固体己二胺四亚甲基膦酸的制备工艺
JP5581832B2 (ja) * 2010-06-11 2014-09-03 三菱瓦斯化学株式会社 高純度アミノメチレンホスホン酸の製造方法
CN103724373A (zh) * 2014-01-02 2014-04-16 山东省泰和水处理有限公司 多聚甲醛生产氨基三亚甲基膦酸的方法
DE102014210378B4 (de) 2014-06-02 2018-10-04 Zschimmer & Schwarz Mohsdorf GmbH &Co.KG. Verfahren zur Herstellung hochreiner Aminoalkylenphosphonsäuren
TR201905374T4 (tr) 2014-06-02 2019-05-21 Zschimmer & Schwarz Mohsdorf Gmbh & Co Kg Kristalin dtpmp üretilmesine yönelik yöntem.
CN113263580A (zh) * 2021-04-23 2021-08-17 广东工业大学 一种多功能床头柜制造设备

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2599807A (en) * 1950-06-01 1952-06-10 Frederick C Bersworth Alkylene polyamine methylene phosphonic acids
NL285361A (cs) * 1961-11-13 1900-01-01
US3738937A (en) * 1970-05-08 1973-06-12 Textilana Corp Polyalkylene polyamino polykis methylene phosphonic acids and salts thereof and methods for producing same
NL7903500A (nl) * 1979-05-04 1980-11-06 Philips Nv Verbrandingsflitslamp en flitsinrichting voorzien van verscheidene verbrandingsflitslampen.
EP0225409A1 (en) * 1985-12-02 1987-06-16 The Dow Chemical Company Organic amine phosphonic acid complexes for the treatment of calcific tumors
US4937333A (en) * 1989-08-04 1990-06-26 The Dow Chemical Company Method for purifying aminomethylenephosphonic acids for pharmaceutical use
GB8903023D0 (en) * 1989-02-10 1989-03-30 Parker David Chemical compounds
DE3911816A1 (de) * 1989-04-11 1990-10-25 Hoechst Ag Substituierte 1,4,7,10-tetraazacyclotridecane, verfahren zu deren herstellung sowie verwendung derselben zur markierung von substanzen mit radionukliden
JP6257193B2 (ja) 2013-07-12 2018-01-10 株式会社神戸製鋼所 肉盛溶接用フラックス入りワイヤ

Also Published As

Publication number Publication date
AU6023790A (en) 1991-02-07
KR0178779B1 (ko) 1999-05-15
NO970653D0 (no) 1997-02-12
PL286349A1 (en) 1991-05-20
CN1031191C (zh) 1996-03-06
SK279107B6 (sk) 1998-06-03
PT94188B (pt) 1996-12-31
ATE140459T1 (de) 1996-08-15
YU47368B (sh) 1995-01-31
NO178196B (no) 1995-10-30
HK1007558A1 (en) 2003-07-10
DE69027818T2 (de) 1996-11-21
LV10718A (lv) 1995-06-20
ZA905564B (en) 1992-03-25
LV10718B (en) 1996-04-20
RO105967B1 (ro) 1993-01-30
CA2020950A1 (en) 1991-02-05
SK379690A3 (en) 1998-06-03
NZ234464A (en) 1994-06-27
DD297414A5 (de) 1992-01-09
AP9000202A0 (en) 1990-10-31
CN1091744A (zh) 1994-09-07
OA09300A (en) 1992-09-15
IL110861A0 (en) 1994-11-28
KR0178877B1 (ko) 1999-05-15
US4937333A (en) 1990-06-26
NO903419D0 (no) 1990-08-03
NO178196C (no) 1996-02-07
EG19250A (en) 1994-09-29
RU1838321C (ru) 1993-08-30
MA21922A1 (fr) 1991-04-01
PT94188A (pt) 1991-04-18
IL110861A (en) 1999-07-14
HUT54698A (en) 1991-03-28
SA90110175B1 (ar) 2004-03-09
NZ247888A (en) 1994-07-26
FI105033B (fi) 2000-05-31
NO970653L (no) 1991-02-05
CN1024196C (zh) 1994-04-13
PL166453B1 (pl) 1995-05-31
CA2020950C (en) 2000-04-11
JP2922263B2 (ja) 1999-07-19
HU205128B (en) 1992-03-30
BR1101174A (pt) 2000-08-08
AU634267B2 (en) 1993-02-18
IL95094A0 (en) 1991-06-10
EP0411941A2 (en) 1991-02-06
DK0411941T3 (da) 1996-11-11
NO903419L (no) 1991-02-05
BG92627A (bg) 1993-12-24
EP0411941B1 (en) 1996-07-17
ES2090105T3 (es) 1996-10-16
EP0411941A3 (en) 1992-04-15
KR910004642A (ko) 1991-03-29
PL164908B1 (pl) 1994-10-31
CN1049351A (zh) 1991-02-20
CZ379690A3 (cs) 2000-08-16
PH26901A (en) 1992-12-03
DE69027818D1 (de) 1996-08-22
BR9003694A (pt) 1991-09-03
AP163A (en) 1992-01-11
FI903864A0 (fi) 1990-08-03
IE902812A1 (en) 1991-02-27
BG60519B1 (bg) 1995-07-28
HU904890D0 (en) 1991-01-28
GR3020932T3 (en) 1996-12-31
CZ290556B6 (cs) 2002-08-14
DZ1436A1 (fr) 2004-09-13
JPH0366697A (ja) 1991-03-22
YU145390A (sh) 1992-09-07

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