IL94854A - 1,2,3,4-Tetrahydro-9-Acridineamino (cyclohexane carboxylic acid and related compounds, process for their preparation and use as drugs - Google Patents

1,2,3,4-Tetrahydro-9-Acridineamino (cyclohexane carboxylic acid and related compounds, process for their preparation and use as drugs

Info

Publication number
IL94854A
IL94854A IL9485490A IL9485490A IL94854A IL 94854 A IL94854 A IL 94854A IL 9485490 A IL9485490 A IL 9485490A IL 9485490 A IL9485490 A IL 9485490A IL 94854 A IL94854 A IL 94854A
Authority
IL
Israel
Prior art keywords
compound
formula
loweralkyl
hydrogen
tetrahydro
Prior art date
Application number
IL9485490A
Other languages
English (en)
Hebrew (he)
Other versions
IL94854A0 (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL94854A0 publication Critical patent/IL94854A0/xx
Publication of IL94854A publication Critical patent/IL94854A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL9485490A 1989-06-26 1990-06-24 1,2,3,4-Tetrahydro-9-Acridineamino (cyclohexane carboxylic acid and related compounds, process for their preparation and use as drugs IL94854A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/371,228 US4999358A (en) 1989-06-26 1989-06-26 (1,2,3,4-tetrahydro-9-acridinimino)cyclohexane carboxylic acid and related compounds

Publications (2)

Publication Number Publication Date
IL94854A0 IL94854A0 (en) 1991-04-15
IL94854A true IL94854A (en) 1994-08-26

Family

ID=23463058

Family Applications (3)

Application Number Title Priority Date Filing Date
IL9485490A IL94854A (en) 1989-06-26 1990-06-24 1,2,3,4-Tetrahydro-9-Acridineamino (cyclohexane carboxylic acid and related compounds, process for their preparation and use as drugs
IL10700190A IL107001A (en) 1989-06-26 1990-06-24 History of acridinamino and pharmaceutical preparations containing them
IL107001A IL107001A0 (en) 1989-06-26 1993-09-14 Tetrahydroacridine amino compounds and pharmaceutical compositions containing them

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL10700190A IL107001A (en) 1989-06-26 1990-06-24 History of acridinamino and pharmaceutical preparations containing them
IL107001A IL107001A0 (en) 1989-06-26 1993-09-14 Tetrahydroacridine amino compounds and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US4999358A (no)
EP (1) EP0405342B1 (no)
JP (1) JP2600013B2 (no)
KR (1) KR0163186B1 (no)
AT (1) ATE115133T1 (no)
AU (1) AU625221B2 (no)
CA (1) CA2019717C (no)
DE (1) DE69014730T2 (no)
DK (1) DK0405342T3 (no)
ES (1) ES2064533T3 (no)
FI (1) FI96307C (no)
IE (1) IE65462B1 (no)
IL (3) IL94854A (no)
NO (1) NO177053C (no)
NZ (1) NZ234199A (no)
PT (1) PT94472B (no)
ZA (1) ZA904914B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2640508B1 (fr) * 1988-12-19 1994-07-01 Dietlin Francois Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire
US5149813A (en) * 1989-06-26 1992-09-22 Hoechst-Roussel Pharmaceuticals Incorporated Process for (1,2,3,4-tetrahydro-9-acridinimino)cyclohexane carboxylic acid and related compounds
US6100276A (en) * 1996-04-12 2000-08-08 Aventis Pharmaceuticals Inc. Isatin derivatives as acetylcholinesterase inhibitors and analgesics
EP0840770A4 (en) * 1996-05-23 2002-03-20 Ian Alexander Gilmour PROCESS FOR THE EXTRACTION OF PROANTHOCYANIDINES FROM BOTANICAL SUBSTANCES
CN1572299A (zh) 1998-09-30 2005-02-02 武田药品工业株式会社 改善膀胱排泄能力的药物
US8328939B2 (en) * 2004-05-12 2012-12-11 Applied Materials, Inc. Diffuser plate with slit valve compensation
US9221760B2 (en) * 2011-05-09 2015-12-29 Van Andel Research Institute Autophagy inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB595603A (en) * 1944-08-21 1947-12-10 Ward Blenkinsop & Co Ltd Process for the production of arylamino acridine derivatives
DK569087A (da) * 1986-10-31 1988-05-01 Sumitomo Pharma Quinolin-derivater, deres fremstilling og anvendelse
US4851536A (en) * 1987-05-07 1989-07-25 American Home Products Corporation Cyclohexylquinolines as inhibitors of interleukin 1
EP0306826A1 (en) * 1987-09-08 1989-03-15 Hoechst-Roussel Pharmaceuticals Incorporated N-(substituted alkylidene)fused bicycloalkylidene and hetero-alkylidene quinolinamines, a process for their preparation and their use as medicaments
IL87861A0 (en) * 1987-10-05 1989-03-31 Pfizer 4-aminopyridine derivatives

Also Published As

Publication number Publication date
JPH0395161A (ja) 1991-04-19
FI96307B (fi) 1996-02-29
ES2064533T3 (es) 1995-02-01
IL107001A0 (en) 1993-12-28
CA2019717C (en) 2001-01-23
PT94472A (pt) 1991-02-08
IL94854A0 (en) 1991-04-15
EP0405342A1 (en) 1991-01-02
EP0405342B1 (en) 1994-12-07
IE902290L (en) 1990-12-26
NZ234199A (en) 1992-05-26
FI903181A0 (fi) 1990-06-25
US4999358A (en) 1991-03-12
ZA904914B (en) 1992-02-26
IE902290A1 (en) 1991-01-16
NO902813L (no) 1990-12-27
AU625221B2 (en) 1992-07-02
IE65462B1 (en) 1995-11-01
NO177053C (no) 1995-07-12
IL107001A (en) 1994-10-21
PT94472B (pt) 1997-05-28
DE69014730T2 (de) 1995-05-11
DK0405342T3 (da) 1995-05-15
KR910000652A (ko) 1991-01-29
DE69014730D1 (de) 1995-01-19
NO902813D0 (no) 1990-06-25
AU5775390A (en) 1991-01-03
JP2600013B2 (ja) 1997-04-16
FI96307C (fi) 1996-06-10
CA2019717A1 (en) 1990-12-26
KR0163186B1 (ko) 1998-12-01
NO177053B (no) 1995-04-03
ATE115133T1 (de) 1994-12-15

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Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)
RH Patent void