IL94649A - Cytosine dahaminase is heat stable - Google Patents

Cytosine dahaminase is heat stable

Info

Publication number
IL94649A
IL94649A IL9464990A IL9464990A IL94649A IL 94649 A IL94649 A IL 94649A IL 9464990 A IL9464990 A IL 9464990A IL 9464990 A IL9464990 A IL 9464990A IL 94649 A IL94649 A IL 94649A
Authority
IL
Israel
Prior art keywords
cdase
sequence
yeast
protein
thermally stable
Prior art date
Application number
IL9464990A
Other languages
English (en)
Hebrew (he)
Other versions
IL94649A0 (en
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/531,646 external-priority patent/US5338678A/en
Application filed by Oncogen filed Critical Oncogen
Publication of IL94649A0 publication Critical patent/IL94649A0/xx
Publication of IL94649A publication Critical patent/IL94649A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL9464990A 1989-06-09 1990-06-06 Cytosine dahaminase is heat stable IL94649A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36502089A 1989-06-09 1989-06-09
US07/531,646 US5338678A (en) 1989-06-09 1990-06-01 Expression of DNA sequences encoding a thermally stable cytosine deaminase from saccharomyces

Publications (2)

Publication Number Publication Date
IL94649A0 IL94649A0 (en) 1991-04-15
IL94649A true IL94649A (en) 1995-11-27

Family

ID=27002759

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9464990A IL94649A (en) 1989-06-09 1990-06-06 Cytosine dahaminase is heat stable

Country Status (21)

Country Link
US (1) US5545548A (zh)
EP (1) EP0402108B1 (zh)
JP (1) JP3001933B2 (zh)
CN (1) CN1052263C (zh)
AT (1) ATE118040T1 (zh)
CA (1) CA2018273C (zh)
CZ (1) CZ283492B6 (zh)
DE (1) DE69016502T2 (zh)
DK (1) DK0402108T3 (zh)
ES (1) ES2070277T3 (zh)
FI (1) FI95046C (zh)
GR (1) GR3015207T3 (zh)
IE (1) IE66054B1 (zh)
IL (1) IL94649A (zh)
MY (1) MY105816A (zh)
NO (1) NO301487B1 (zh)
NZ (1) NZ233949A (zh)
OA (1) OA09214A (zh)
PL (1) PL165149B1 (zh)
PT (1) PT94331B (zh)
YU (1) YU112090A (zh)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555370B1 (en) 1990-11-13 2003-04-29 Immunex Corporation Bifunctional selectable fusion genes
US5358866A (en) * 1991-07-03 1994-10-25 The United States Of America As Represented By The Department Of Health And Human Services Cytosine deaminase negative selection system for gene transfer techniques and therapies
EP0804590A1 (en) * 1993-05-21 1997-11-05 Targeted Genetics Corporation Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene
US6451571B1 (en) 1994-05-02 2002-09-17 University Of Washington Thymidine kinase mutants
US5856153A (en) * 1994-11-17 1999-01-05 Cayla Suicide genes and new associations of pyrimidine nucleobase and nucleoside analogs with new suicide genes for gene therapy of acquired diseases
CA2243985C (en) * 1997-09-11 2004-08-10 F. Hoffmann-La Roche Ag Thermostable dna polymerases incorporating nucleoside triphosphates labeled with fluorescein family dyes
GB9810752D0 (en) * 1998-05-19 1998-07-15 Glaxo Group Ltd Cystosine deaminase gene
US6962702B2 (en) 1998-06-22 2005-11-08 Immunomedics Inc. Production and use of novel peptide-based agents for use with bi-specific antibodies
US6656917B1 (en) 1999-06-30 2003-12-02 Marker Gene Technologies, Inc. Compositions and methods for targeted enzymatic release of cell regulatory compounds
US8716558B2 (en) 1999-06-30 2014-05-06 Marker Gene Technologies, Inc. Method of altering glycosylation of proteins in response to nojirimycin glucuronide in a plant cell expressing glucuronidase
US20060147420A1 (en) * 2004-03-10 2006-07-06 Juan Fueyo Oncolytic adenovirus armed with therapeutic genes
KR20120068769A (ko) 2002-07-15 2012-06-27 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 음이온성 인지질 및 아미노인지질에 결합하는 선택된 항체 및 치료하는데 있어서 이의 용도
EP1925626A1 (en) 2003-07-21 2008-05-28 Transgene S.A. Novel multifunctional cytokines
EP1897938B9 (en) * 2003-07-21 2011-08-31 Transgene SA Polypeptide having an improved cytosine deaminase activity
CA2534639C (en) 2003-07-31 2013-07-30 Immunomedics, Inc. Anti-cd19 antibodies
DK1760148T3 (da) * 2004-04-28 2013-09-02 Amano Enzyme Inc Amp-deaminase, som stammer fra streptomyces og brugen deraf
JP5809415B2 (ja) 2007-11-09 2015-11-10 ペレグリン ファーマシューティカルズ，インコーポレーテッド 抗ｖｅｇｆ抗体の組成物および方法
US20090263884A1 (en) * 2008-04-22 2009-10-22 Organica Biotech, Inc. Multi-action drain cleaning composition and method
CN102227501B (zh) 2008-09-26 2016-11-16 托卡根公司 基因治疗载体和胞嘧啶脱氨酶
CN103045573B (zh) * 2012-12-10 2015-03-18 浙江工业大学 冬虫夏草胞嘧啶脱氨酶、编码基因及其应用
CN103031296B (zh) * 2012-12-10 2014-12-17 浙江工业大学 冬虫夏草dCMP脱氨酶、编码基因及其应用
CN109207535B (zh) * 2018-09-20 2021-06-25 新乡拓新药业股份有限公司 利用铜绿假单胞菌合成尿嘧啶的方法
CN116143947B (zh) * 2023-01-16 2024-05-24 中国科学院青岛生物能源与过程研究所 一种酵母胞嘧啶脱氨酶融合蛋白及其突变体和应用

Also Published As

Publication number Publication date
IE902079L (en) 1990-12-09
FI902855A0 (fi) 1990-06-07
CZ283492B6 (cs) 1998-04-15
PL165149B1 (pl) 1994-11-30
NO902551L (no) 1990-12-10
CA2018273A1 (en) 1990-12-09
CN1052263C (zh) 2000-05-10
FI95046B (fi) 1995-08-31
DE69016502T2 (de) 1995-06-01
DE69016502D1 (de) 1995-03-16
PT94331A (pt) 1991-03-20
IE66054B1 (en) 1995-12-13
CA2018273C (en) 1999-04-06
YU112090A (en) 1992-05-28
NO301487B1 (no) 1997-11-03
US5545548A (en) 1996-08-13
CN1050221A (zh) 1991-03-27
EP0402108A1 (en) 1990-12-12
EP0402108B1 (en) 1995-02-01
CS286590A3 (en) 1992-02-19
GR3015207T3 (en) 1995-05-31
NZ233949A (en) 1992-06-25
MY105816A (en) 1995-01-30
ATE118040T1 (de) 1995-02-15
FI95046C (fi) 1995-12-11
ES2070277T3 (es) 1995-06-01
IL94649A0 (en) 1991-04-15
PT94331B (pt) 1997-04-30
JPH04131084A (ja) 1992-05-01
DK0402108T3 (da) 1995-04-10
PL285552A1 (en) 1991-02-25
NO902551D0 (no) 1990-06-08
JP3001933B2 (ja) 2000-01-24
OA09214A (en) 1992-06-30

Similar Documents

Publication Publication Date Title
US5338678A (en) Expression of DNA sequences encoding a thermally stable cytosine deaminase from saccharomyces
CA2018273C (en) Thermally stable cytosine deaminase
Palmer et al. Isolation of protein FA, a product of the mob locus required for molybdenum cofactor biosynthesis in Escherichia coli
US6406899B1 (en) Highly active alkaline phosphatase
US6280993B1 (en) Gene encoding class I collagenase
US5908772A (en) Gene encoding lacto-N-biosidase
Patil et al. Cloning, nucleotide sequence, overexpression, and inactivation of the Escherichia coli 2-keto-4-hydroxyglutarate aldolase gene
JPH02177887A (ja) グルコース―６―リン酸デヒドロゲナーゼ遺伝子
Reddy et al. Overproduction and rapid purification of the phosphoenolpyruvate: sugar phosphotransferase system proteins enzyme I, HPr, and Protein IIIGlc of Escherichia coli
US6323017B1 (en) Platelet activating factor acetylhydrolase, and gene thereof
EP0445097B1 (en) Method for protein N-myristoylation
Shioi et al. Purification by affinity chromatography and properties of uroporphyrinogen I synthetase from Chlorella regularis
JP3486942B2 (ja) 耐熱性エステラーゼ
Chang et al. Expression of Taiwan Banded Krait Phospholipase A2inEscherichia coli, a Fully Active Enzyme Generated by Hydrolyzing with Aminopeptidase
David et al. Cloning, expression, and purification of rat brain protein L-isoaspartyl methyltransferase
Pan et al. Sequence analysis and expression of phospholipase A2 from Taiwan cobra
HU219544B (hu) Eljárás aminoterminális dipeptid vagy dipeptidek polipeptid előanyagról történő eltávolítására
JP2845558B2 (ja) メチオニンアミノペプチダーゼのｄｎａ配列
JP4916602B2 (ja) 耐熱性エステラーゼおよびその遺伝子
Keßler et al. Ser644 is important for catalytic activity but is not involved in cAMP-dependent phosphorylation of yeast 6-phosphofructo-2-kinase
RU2373281C2 (ru) Способ продукции рекомбинантной стафилокиназы при регулировании уровня кислорода
JP2002218986A (ja) 新規グルタミナーゼ及びその製造方法
JPH02308793A (ja) ミコバクテリウム・カンサシ由来のα抗原
JP2004081215A (ja) エステラーゼ遺伝子

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed