IL94592A - Piperidinoalkyl-substituted fused, bicyclic 1,2,4-triazolone and 1.3.5-triazinedione derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

Piperidinoalkyl-substituted fused, bicyclic 1,2,4-triazolone and 1.3.5-triazinedione derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL94592A
IL94592A IL9459290A IL9459290A IL94592A IL 94592 A IL94592 A IL 94592A IL 9459290 A IL9459290 A IL 9459290A IL 9459290 A IL9459290 A IL 9459290A IL 94592 A IL94592 A IL 94592A
Authority
IL
Israel
Prior art keywords
group
formula
compound
atom
halogen atom
Prior art date
Application number
IL9459290A
Other languages
English (en)
Other versions
IL94592A0 (en
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1310346A external-priority patent/JPH03170431A/ja
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of IL94592A0 publication Critical patent/IL94592A0/xx
Publication of IL94592A publication Critical patent/IL94592A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL9459290A 1989-06-05 1990-06-01 Piperidinoalkyl-substituted fused, bicyclic 1,2,4-triazolone and 1.3.5-triazinedione derivatives, their preparation and pharmaceutical compositions containing them IL94592A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP14239789 1989-06-05
JP18861789 1989-07-20
JP20203989 1989-08-03
JP1310346A JPH03170431A (ja) 1989-11-29 1989-11-29 心臓疾患治療剤

Publications (2)

Publication Number Publication Date
IL94592A0 IL94592A0 (en) 1991-04-15
IL94592A true IL94592A (en) 1994-07-31

Family

ID=27472451

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9459290A IL94592A (en) 1989-06-05 1990-06-01 Piperidinoalkyl-substituted fused, bicyclic 1,2,4-triazolone and 1.3.5-triazinedione derivatives, their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US5232924A (es)
EP (1) EP0401707B1 (es)
KR (1) KR910000755A (es)
CN (1) CN1049161A (es)
AT (1) ATE111911T1 (es)
AU (1) AU628579B2 (es)
CA (1) CA2018220A1 (es)
DE (1) DE69012653T2 (es)
DK (1) DK0401707T3 (es)
ES (1) ES2064530T3 (es)
FI (1) FI902763A7 (es)
HU (1) HUT54365A (es)
IL (1) IL94592A (es)
NO (1) NO174712C (es)
NZ (1) NZ233917A (es)
PT (1) PT94270A (es)
YU (1) YU108790A (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552397A (en) * 1992-05-18 1996-09-03 E. R. Squibb & Sons, Inc. Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase
CA2108245A1 (en) * 1992-11-04 1994-05-05 Gary J. Grover Method for treating myocardial ischemia employing serotonin receptor antagonists
US20080076794A1 (en) * 2004-05-28 2008-03-27 Peter Herold Heterocyclic Compounds And Their Use As Aldosterone Synthase Inhibitors
RU2376307C1 (ru) * 2008-05-27 2009-12-20 Институт органического синтеза им. И.Я. Постовского Уральского отделения Российской академии наук 4-((Z)-4'-ГИДРОКСИБУТЕН-2'-ИЛ)-2-R-6-ФЕНИЛ-1,2,4-ТРИАЗОЛО[5,1-c][1,2,4]ТРИАЗИН-7-ОНЫ
PT2399910E (pt) 2009-02-13 2014-05-02 Shionogi & Co Novo derivado de triazina e composição farmacéutica que contém o mesmo
JP6075621B2 (ja) 2010-08-10 2017-02-08 塩野義製薬株式会社 新規複素環誘導体およびそれらを含有する医薬組成物
EP2604595B1 (en) 2010-08-10 2016-03-16 Shionogi&Co., Ltd. Triazine derivative and pharmaceutical compound that contains same and exhibits analgesic activity
US9266881B2 (en) * 2011-11-14 2016-02-23 Merck Sharp & Dohme Corp. Triazolopyridinone PDE10 inhibitors
JP6124351B2 (ja) 2012-02-09 2017-05-10 塩野義製薬株式会社 複素環および炭素環誘導体
TWI637949B (zh) 2013-06-14 2018-10-11 塩野義製藥股份有限公司 胺基三衍生物及含有其等之醫藥組合物
CN113185521A (zh) * 2021-05-08 2021-07-30 新乡市润宇新材料科技有限公司 一种环丙基开环制备四氢吡咯并[1,2-a]1,3,5-三嗪-4-酮类化合物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH499531A (de) * 1968-05-06 1970-11-30 Agripat Sa Verfahren zur Herstellung neuer Pyrido (1,2-a)-s-triazin-dione
GB1328205A (en) * 1970-10-13 1973-08-30 Lilly Industries Ltd Oxazolo-triazines
US4340597A (en) * 1981-04-13 1982-07-20 Schering Corporation 1-Substituted-4-aryl-1,2,5,6-tetrahydro and hexahydropyridines
DE3173762D1 (de) * 1981-06-15 1986-03-27 Nippon Soda Co Thiazolinotriazine derivatives
DE3126837A1 (de) * 1981-07-08 1983-01-27 Hoechst Ag, 6000 Frankfurt Triazino-(2,1-a)isochinolinderivate

Also Published As

Publication number Publication date
AU628579B2 (en) 1992-09-17
FI902763A0 (fi) 1990-06-04
ATE111911T1 (de) 1994-10-15
NO902439L (no) 1990-12-06
DE69012653D1 (de) 1994-10-27
NO902439D0 (no) 1990-06-01
PT94270A (pt) 1991-02-08
AU5629590A (en) 1990-12-06
ES2064530T3 (es) 1995-02-01
HU903489D0 (en) 1990-10-28
FI902763A7 (fi) 1990-12-06
CN1049161A (zh) 1991-02-13
YU108790A (en) 1991-10-31
HUT54365A (en) 1991-02-28
DK0401707T3 (da) 1994-10-17
NO174712B (no) 1994-03-14
EP0401707B1 (en) 1994-09-21
US5232924A (en) 1993-08-03
NO174712C (no) 1994-06-22
DE69012653T2 (de) 1995-02-09
IL94592A0 (en) 1991-04-15
CA2018220A1 (en) 1990-12-05
KR910000755A (ko) 1991-01-30
EP0401707A1 (en) 1990-12-12
NZ233917A (en) 1991-04-26

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