IL93187A - תכשירי רוקחות המכילים תרכבות חומצה אריל או הטרואריל-1-אלקיל-פירול-2-קרבוקסיליתהמשמשות לטיפול במצבים הקשורים באינטרלויק - Google Patents
תכשירי רוקחות המכילים תרכבות חומצה אריל או הטרואריל-1-אלקיל-פירול-2-קרבוקסיליתהמשמשות לטיפול במצבים הקשורים באינטרלויקInfo
- Publication number
- IL93187A IL93187A IL9318790A IL9318790A IL93187A IL 93187 A IL93187 A IL 93187A IL 9318790 A IL9318790 A IL 9318790A IL 9318790 A IL9318790 A IL 9318790A IL 93187 A IL93187 A IL 93187A
- Authority
- IL
- Israel
- Prior art keywords
- pyrrole
- carboxylic acid
- composition
- alkyl
- biphenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30414189A | 1989-01-31 | 1989-01-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL93187A0 IL93187A0 (en) | 1990-11-05 |
| IL93187A true IL93187A (he) | 1994-12-29 |
Family
ID=23175237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9318790A IL93187A (he) | 1989-01-31 | 1990-01-26 | תכשירי רוקחות המכילים תרכבות חומצה אריל או הטרואריל-1-אלקיל-פירול-2-קרבוקסיליתהמשמשות לטיפול במצבים הקשורים באינטרלויק |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0381141B1 (he) |
| JP (1) | JP2841305B2 (he) |
| KR (1) | KR0139288B1 (he) |
| CN (1) | CN1022754C (he) |
| AR (1) | AR245694A1 (he) |
| AT (1) | ATE135702T1 (he) |
| AU (1) | AU629290B2 (he) |
| CA (1) | CA2008616C (he) |
| DE (1) | DE69025967T2 (he) |
| ES (1) | ES2087093T3 (he) |
| FI (1) | FI900464A0 (he) |
| HU (1) | HU209290B (he) |
| IL (1) | IL93187A (he) |
| NO (1) | NO174887C (he) |
| NZ (1) | NZ232278A (he) |
| PT (1) | PT93009A (he) |
| ZA (1) | ZA90554B (he) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
| ZA90555B (en) * | 1989-01-31 | 1990-10-31 | Merrell Pharma Inc | Method of using aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds in the treatment of interleukin-1 mediated conditions |
| CA2767112C (en) | 2009-07-10 | 2018-06-19 | The General Hospital Corporation | Etomidate analogues that do not inhibit adrenocortical steroid synthesis |
| CN102114430B (zh) * | 2009-12-30 | 2013-06-05 | 上海睿智化学研究有限公司 | 催化剂、其制备方法及n-烷基吡咯衍生物的制备方法 |
| ES2617536T3 (es) | 2012-01-13 | 2017-06-19 | The General Hospital Corporation | Compuestos anestésicos y métodos relacionados de uso |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4112112A (en) * | 1976-06-29 | 1978-09-05 | Merck & Co., Inc. | Pyrrolo[2,1-b] [3]benzazepines useful for producing a skeletal muscle relaxing or tranquilizing effect |
| JPS54128567A (en) * | 1978-03-28 | 1979-10-05 | Teijin Ltd | 1-substituted-4-acyl-2-pyrrolecarboxylic acid derivative |
-
1990
- 1990-01-25 ZA ZA90554A patent/ZA90554B/xx unknown
- 1990-01-25 AR AR90316008A patent/AR245694A1/es active
- 1990-01-25 AU AU48759/90A patent/AU629290B2/en not_active Ceased
- 1990-01-25 CA CA002008616A patent/CA2008616C/en not_active Expired - Fee Related
- 1990-01-26 IL IL9318790A patent/IL93187A/he not_active IP Right Cessation
- 1990-01-29 NZ NZ232278A patent/NZ232278A/en unknown
- 1990-01-29 JP JP2016304A patent/JP2841305B2/ja not_active Expired - Fee Related
- 1990-01-30 EP EP90101809A patent/EP0381141B1/en not_active Expired - Lifetime
- 1990-01-30 DE DE69025967T patent/DE69025967T2/de not_active Expired - Fee Related
- 1990-01-30 AT AT90101809T patent/ATE135702T1/de not_active IP Right Cessation
- 1990-01-30 FI FI900464A patent/FI900464A0/fi not_active IP Right Cessation
- 1990-01-30 ES ES90101809T patent/ES2087093T3/es not_active Expired - Lifetime
- 1990-01-30 PT PT93009A patent/PT93009A/pt not_active Application Discontinuation
- 1990-01-30 HU HU90592A patent/HU209290B/hu not_active IP Right Cessation
- 1990-01-30 NO NO900432A patent/NO174887C/no unknown
- 1990-01-30 KR KR1019900000994A patent/KR0139288B1/ko not_active IP Right Cessation
- 1990-01-31 CN CN90100431A patent/CN1022754C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2087093T3 (es) | 1996-07-16 |
| CN1022754C (zh) | 1993-11-17 |
| HU900592D0 (en) | 1990-04-28 |
| ZA90554B (en) | 1990-10-31 |
| ATE135702T1 (de) | 1996-04-15 |
| EP0381141A2 (en) | 1990-08-08 |
| HU209290B (en) | 1994-04-28 |
| JPH02247165A (ja) | 1990-10-02 |
| PT93009A (pt) | 1990-07-31 |
| AU629290B2 (en) | 1992-10-01 |
| IL93187A0 (en) | 1990-11-05 |
| EP0381141A3 (en) | 1991-11-21 |
| NO174887C (no) | 1994-07-27 |
| NO900432D0 (no) | 1990-01-30 |
| CA2008616A1 (en) | 1990-07-31 |
| AR245694A1 (es) | 1994-02-28 |
| FI900464A0 (fi) | 1990-01-30 |
| NZ232278A (en) | 1992-07-28 |
| HUT53868A (en) | 1990-12-28 |
| KR900011725A (ko) | 1990-08-02 |
| JP2841305B2 (ja) | 1998-12-24 |
| CN1044653A (zh) | 1990-08-15 |
| EP0381141B1 (en) | 1996-03-20 |
| AU4875990A (en) | 1990-08-09 |
| DE69025967D1 (de) | 1996-04-25 |
| CA2008616C (en) | 2000-07-18 |
| NO900432L (no) | 1990-08-01 |
| KR0139288B1 (ko) | 1998-05-15 |
| NO174887B (no) | 1994-04-18 |
| DE69025967T2 (de) | 1996-08-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60225316T2 (de) | Cyanoalkylamino-derivate als protease-hemmer | |
| DE69408750T2 (de) | 4-Aminopyrimidin Derivate | |
| US4714762A (en) | Antiarteriosclerotic substituted benzimidazol-2-yl-and 3H-imidazo[4,5-b]pyridin-2-yl-phenoxy-alkanoic acids and salts and esters thereof | |
| KR100513302B1 (ko) | 3-아미노-1,2-벤조이소옥사졸 유도체, 이의 제조방법및 용도 | |
| US5041554A (en) | Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditions | |
| CA1266271A (en) | 2,5-diaryl tetrahydrothiophenes and analogs thereof as paf-antagonists | |
| FR2700472A1 (fr) | Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2. | |
| KR900006118B1 (ko) | 4-퀴놀론 유도체의 제법 | |
| CA2008616C (en) | Aryl- or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditions | |
| US4590205A (en) | Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes | |
| US5039695A (en) | Method of using aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds in the treatment of interleukin-1 mediated conditions | |
| FR2534582A1 (fr) | Nouveaux derives de benzofuranne et de benzothiophene, utiles comme agents anti-hyperuricemie et anti-hypertension, et leur procede de fabrication | |
| US4980371A (en) | Antiretroviral furan ketones | |
| PT92633A (pt) | Processo para a preparacao de derivados cetonicos do furano com accao anti-retroviral e de composicoes farmaceuticas que os contem | |
| AU625688B2 (en) | Method of using aryl- or heteroaryl-1-alkyl-pyrrole-2- carboxylic acid compounds in the treatment of interleukin-1 mediated conditions | |
| US20090270494A1 (en) | Salts of Dihydroxyanthraquinone Carboxylic Acids and Their Therapeutic Use | |
| JP3164157B2 (ja) | 抗炎症薬として有用なジヒドロベンゾフランおよび関連化合物 | |
| CA2313302C (fr) | Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
| FR2634764A1 (fr) | Heterocycles oxaza et compositions pharmaceutiques les contenant | |
| JPS63264580A (ja) | ３−（２−ハロアルキル）−１，４−オキサチインおよび２−（２−ハロアルキル）−１，４−ジチイン | |
| JPH05301865A (ja) | 新規テトラヒドロフラン誘導体及びテトラヒドロチオフェン誘導体 | |
| EP0374885B1 (en) | Antiretroviral aryloxy substituted furan ketones | |
| EP0410379B1 (en) | Pharmaceutically active 3-aryl and 3-heteroaryl-2-fluoro-1-olefins | |
| FR2573761A1 (fr) | Acylamino hydroxyalcanoyl amino et imino acides et esters a action therapeutique | |
| US4607105A (en) | 3-cyclobutene-1,2-dione intermediates |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void | ||
| HC | Change of name of proprietor(s) |
Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC. |