IL91977A - B-D-Phenylthyloxylosides, their preparation and pharmaceutical preparations containing them - Google Patents

B-D-Phenylthyloxylosides, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL91977A
IL91977A IL9197789A IL9197789A IL91977A IL 91977 A IL91977 A IL 91977A IL 9197789 A IL9197789 A IL 9197789A IL 9197789 A IL9197789 A IL 9197789A IL 91977 A IL91977 A IL 91977A
Authority
IL
Israel
Prior art keywords
preparation
mol
group
tri
thio
Prior art date
Application number
IL9197789A
Other languages
English (en)
Hebrew (he)
Other versions
IL91977A0 (en
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8813688A external-priority patent/FR2638749B1/fr
Priority claimed from FR8908253A external-priority patent/FR2648819B1/fr
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Publication of IL91977A0 publication Critical patent/IL91977A0/xx
Publication of IL91977A publication Critical patent/IL91977A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/01—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton
    • C07C323/09—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/02—Monothiocarbamic acids; Derivatives thereof
    • C07C333/04—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IL9197789A 1988-10-18 1989-10-12 B-D-Phenylthyloxylosides, their preparation and pharmaceutical preparations containing them IL91977A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8813688A FR2638749B1 (fr) 1988-10-18 1988-10-18 Nouveaux (beta)-d-phenyl-thioxylosides, leur procede de preparation et leur utilisation en therapeutique
FR8908253A FR2648819B1 (fr) 1989-06-21 1989-06-21 Nouveaux (beta)-d-phenyl-thioxylosides, leur procede de preparation et leur utilisation en therapeutique

Publications (2)

Publication Number Publication Date
IL91977A0 IL91977A0 (en) 1990-07-12
IL91977A true IL91977A (en) 1994-08-26

Family

ID=26226940

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9197789A IL91977A (en) 1988-10-18 1989-10-12 B-D-Phenylthyloxylosides, their preparation and pharmaceutical preparations containing them

Country Status (21)

Country Link
US (1) US5101048A (no)
EP (1) EP0365397B1 (no)
JP (1) JPH0826058B2 (no)
KR (1) KR930005990B1 (no)
CN (1) CN1024801C (no)
AT (1) ATE112283T1 (no)
AU (1) AU633853B2 (no)
CA (1) CA2000769A1 (no)
DE (1) DE68918548T2 (no)
DK (1) DK171401B1 (no)
ES (1) ES2064473T3 (no)
FI (1) FI98372C (no)
HU (1) HU203248B (no)
IE (1) IE63544B1 (no)
IL (1) IL91977A (no)
NO (1) NO171166C (no)
NZ (1) NZ231024A (no)
PT (1) PT92014B (no)
RU (1) RU1780538C (no)
UA (1) UA15921A (no)
YU (1) YU47072B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2660313B1 (fr) * 1990-04-02 1992-07-03 Fournier Ind & Sante Nouveau sulfonyl-phenyl-betha-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
US5689657A (en) * 1991-03-30 1997-11-18 Deutsche Itt Industries Gmbh Apparatus and methods for bus arbitration in a multimaster system
HUP9601756A3 (en) * 1996-06-25 1999-05-28 Richter Gedeon Vegyeszet New anticoagulant glycosides and pharmaceutical compositions containing them
HUP9603341A3 (en) * 1996-12-04 1999-05-28 Richter Gedeon Vegyeszet Glucosides as blood-clotting-inhibitors and pharmaceutical compositions containing them
HUP9702348A3 (en) * 1997-12-04 2000-12-28 Richter Gedeon Vegyeszet New anticoagulant glycosides and pharmaceutical conew anticoagulant glycosides and pharmaceutical compositions containing them mpositions containing them
US6291433B1 (en) 1999-06-11 2001-09-18 Fournier Industrie Et Sante Derivatives of α-D-Thioxyloside and their use against atheroma
FR2860234B1 (fr) * 2003-09-25 2005-12-23 Fournier Lab Sa Nouveaux derives 666 du thioxylose
FR2883561B1 (fr) * 2005-03-25 2009-03-20 Fournier S A Sa Lab Nouveaux composes derives du 5-thioxylose et leur utilisation therapeutique
FR2903698B1 (fr) * 2006-07-13 2009-01-30 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose.
FR2906248B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
FR2906247B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
AU2013395144B2 (en) * 2013-07-25 2017-12-14 Scinopharm Taiwan, Ltd. Process for the production of Fondaparinux sodium

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3243425A (en) * 1962-10-29 1966-03-29 Purdue Research Foundation Novel sulfur-containing compounds
GR71911B (no) * 1978-08-31 1983-08-16 Lilly Co Eli
US4264605A (en) * 1978-08-31 1981-04-28 Eli Lilly And Company 1-Benzoyl-3-(aryloxy- or arylthiopyridinyl) urea compounds
FR2492830A1 (fr) * 1980-10-29 1982-04-30 Sori Soc Rech Ind Nouveaux composes appartenant a la famille des benzoyl- et a-hydroxybenzyl-phenyl-osides, leur procede de preparation et leur application en therapeutique
DE3172379D1 (en) * 1980-12-09 1985-10-24 Seikagaku Kogyo Co Ltd D-xylopyranoside series compounds and therapeutical compositions containing same
US4584012A (en) * 1982-11-10 1986-04-22 Monsanto Company 1-phenylthio-1-cyclopropanecarbonitrile and substituted phenylthio derivatives thereof as crop protectants
FR2549476B1 (fr) * 1983-07-20 1986-04-25 Rech Ind Benzyl-phenyl-osides, procede de preparation et utilisation en therapeutique
DE3543036A1 (de) * 1985-12-05 1987-06-11 Bayer Ag Verfahren zur herstellung von 4-mercaptobenzonitrilen und neue 4-mercaptobenzonitrile
FR2614893B1 (fr) * 1987-05-04 1989-12-22 Fournier Innovation Synergie Nouveaux b-d-phenyl-thioxylosides, leur procede de preparation et leur application en therapeutique
ATE92074T1 (de) * 1988-11-03 1993-08-15 Fournier Ind & Sante Beta-d-phenylthioxyloside, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.

Also Published As

Publication number Publication date
IE63544B1 (en) 1995-05-17
DE68918548D1 (de) 1994-11-03
YU47072B (sh) 1994-12-28
FI98372C (fi) 1997-06-10
EP0365397A3 (en) 1990-09-05
HU203248B (en) 1991-06-28
UA15921A (uk) 1997-06-30
NO894134D0 (no) 1989-10-17
CN1024801C (zh) 1994-06-01
PT92014A (pt) 1990-04-30
EP0365397A2 (fr) 1990-04-25
EP0365397B1 (fr) 1994-09-28
JPH0826058B2 (ja) 1996-03-13
NZ231024A (en) 1990-12-21
YU201789A (en) 1991-02-28
KR900006312A (ko) 1990-05-07
IE893240L (en) 1990-04-18
DK171401B1 (da) 1996-10-14
FI98372B (fi) 1997-02-28
KR930005990B1 (ko) 1993-07-01
HU895336D0 (en) 1990-01-28
AU4356089A (en) 1990-04-26
HUT52106A (en) 1990-06-28
PT92014B (pt) 1995-05-31
DK516189A (da) 1990-04-19
US5101048A (en) 1992-03-31
DE68918548T2 (de) 1995-02-16
NO894134L (no) 1990-04-19
DK516189D0 (da) 1989-10-17
ES2064473T3 (es) 1995-02-01
NO171166B (no) 1992-10-26
RU1780538C (ru) 1992-12-07
AU633853B2 (en) 1993-02-11
NO171166C (no) 1993-02-03
FI894900A0 (fi) 1989-10-16
IL91977A0 (en) 1990-07-12
ATE112283T1 (de) 1994-10-15
CA2000769A1 (en) 1990-04-18
CN1041948A (zh) 1990-05-09
JPH02164893A (ja) 1990-06-25

Similar Documents

Publication Publication Date Title
IL91977A (en) B-D-Phenylthyloxylosides, their preparation and pharmaceutical preparations containing them
US4996347A (en) Novel beta-d-phenylthioxylosides, their method of preparation and their use as therapeutics
KR20050056194A (ko) 선택적인 아릴 5-티오-β-Ｄ-알도헥소피라노시드의 제조방법
KR910008109B1 (ko) 벤질페닐 오사이드 유도체의 제조방법
IE903414A1 (en) Novel benzopyranone-ß-D-thioxylosides, their method of preparation and their use in therapy
US5246961A (en) β-d-phenylthioxylosides, and their use as therapeutic agents
US20040019198A1 (en) Method of forming glycosidic bonds from thioglycosides using an N,N-dialkylsulfinamide
CA2039249C (en) Sulfonylphenyl-.beta.-d-thioxylosides, their method of preparation and their use in therapeutics
SK175798A3 (en) Novel anticoagulant glycosides and pharmaceutical compositions thereof
KR0168876B1 (ko) 글루코피라노오스 유도체 염 및 그 중간체
DD294029A5 (de) Neue beta-d-phenyl-thioxyloxide, verfahren zu ihrer herstellung und ihre therapeutische verwendung
FR2652353A1 (fr) Nouveaux benzopyran-2-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.