IL91552A - 4-] 4-) 3-Benziazothiazolyl (1-piperazinyl [Butyl's bridged bicarbonate with antipsychotic activity and pharmaceuticals containing the same - Google Patents

4-] 4-) 3-Benziazothiazolyl (1-piperazinyl [Butyl's bridged bicarbonate with antipsychotic activity and pharmaceuticals containing the same

Info

Publication number
IL91552A
IL91552A IL9155289A IL9155289A IL91552A IL 91552 A IL91552 A IL 91552A IL 9155289 A IL9155289 A IL 9155289A IL 9155289 A IL9155289 A IL 9155289A IL 91552 A IL91552 A IL 91552A
Authority
IL
Israel
Prior art keywords
antipsychotic
piperazinyl
formula
benzisothiazolyl
compound
Prior art date
Application number
IL9155289A
Other languages
English (en)
Hebrew (he)
Other versions
IL91552A0 (en
Original Assignee
Pfizer Inc New York N Y U S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc New York N Y U S A filed Critical Pfizer Inc New York N Y U S A
Publication of IL91552A0 publication Critical patent/IL91552A0/xx
Publication of IL91552A publication Critical patent/IL91552A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL9155289A 1988-09-16 1989-09-07 4-] 4-) 3-Benziazothiazolyl (1-piperazinyl [Butyl's bridged bicarbonate with antipsychotic activity and pharmaceuticals containing the same IL91552A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1988/003230 WO1990002552A1 (en) 1988-09-16 1988-09-16 Antipsychotic 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butyl bridged bicyclic imides

Publications (2)

Publication Number Publication Date
IL91552A0 IL91552A0 (en) 1990-04-29
IL91552A true IL91552A (en) 1994-02-27

Family

ID=22208913

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9155289A IL91552A (en) 1988-09-16 1989-09-07 4-] 4-) 3-Benziazothiazolyl (1-piperazinyl [Butyl's bridged bicarbonate with antipsychotic activity and pharmaceuticals containing the same

Country Status (20)

Country Link
US (1) US5077295A (no)
EP (1) EP0364091B1 (no)
JP (1) JPH0631231B2 (no)
KR (1) KR930002568B1 (no)
AT (1) ATE92063T1 (no)
AU (1) AU607354B2 (no)
CA (1) CA1339314C (no)
DE (1) DE68907845T2 (no)
DK (1) DK175200B1 (no)
ES (1) ES2058542T3 (no)
FI (1) FI911285A0 (no)
HU (1) HUT61760A (no)
IE (1) IE61413B1 (no)
IL (1) IL91552A (no)
MY (1) MY104207A (no)
NO (1) NO911042L (no)
NZ (1) NZ230672A (no)
PT (1) PT91703B (no)
WO (1) WO1990002552A1 (no)
ZA (1) ZA897049B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235283A (en) * 1991-02-07 1993-08-10 Siemens Aktiengesellschaft Gradient coil system for a nuclear magnetic resonance tomography apparatus which reduces acoustic noise
ATE254600T1 (de) * 1996-02-13 2003-12-15 Pfizer Prodrogen von 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl ethyl)-6-chloro-1,3-dihydro-2h-indol- 2-on
US6084097A (en) * 1997-10-20 2000-07-04 Council Of Scientific & Industrial Research Methods for preparing 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl] propanes
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
JPS5995267A (ja) * 1982-11-25 1984-06-01 Eisai Co Ltd カルボン酸イミド誘導体およびその製造方法
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4562255A (en) * 1984-03-30 1985-12-31 American Home Products Corporation Substituted bi-alicyclic imides
US4585773A (en) * 1984-07-11 1986-04-29 Bristol-Myers Company Isoindolinyl-alkyl-piperazines
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
JPH0625181B2 (ja) * 1985-03-27 1994-04-06 住友製薬株式会社 新規なイミド誘導体
US4656173A (en) * 1985-04-24 1987-04-07 Bristol-Myers Company Antipsychotic benzisothiazole S-oxide compound
HUT43600A (en) * 1985-06-22 1987-11-30 Sandoz Ag Process for production of new thiazole derivatives and medical compound containing those
US4732984A (en) * 1985-10-17 1988-03-22 American Home Products Corporation Piperazinoisothiazolones with psychotropic activity
JPS6310760A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd イミド誘導体の新規製造法
JPS6310786A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd 新規イミド誘導体およびその製造法
DD263531A5 (de) * 1986-10-21 1989-01-04 ������@���Kk�� Verfahren zur herstellung von verbrueckten bicyclischen imidverbindungen
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
US4883795A (en) * 1988-01-22 1989-11-28 Pfizer Inc. Piperazinyl-heterocyclic compounds
JPH0310760A (ja) * 1989-06-09 1991-01-18 Nippon Spindle Mfg Co Ltd 結晶質脆性材料切断用ワイヤソー

Also Published As

Publication number Publication date
DK456389D0 (da) 1989-09-15
AU607354B2 (en) 1991-02-28
DK175200B1 (da) 2004-07-05
EP0364091B1 (en) 1993-07-28
JPH0631231B2 (ja) 1994-04-27
WO1990002552A1 (en) 1990-03-22
ZA897049B (en) 1991-04-24
DK456389A (da) 1990-03-17
MY104207A (en) 1994-02-28
KR900004730A (ko) 1990-04-12
IL91552A0 (en) 1990-04-29
HUT61760A (en) 1993-03-01
IE61413B1 (en) 1994-11-02
DE68907845D1 (de) 1993-09-02
PT91703B (pt) 1995-07-18
EP0364091A1 (en) 1990-04-18
ES2058542T3 (es) 1994-11-01
NO911042L (no) 1991-05-15
KR930002568B1 (ko) 1993-04-03
PT91703A (pt) 1990-03-30
NO911042D0 (no) 1991-03-15
JPH02121986A (ja) 1990-05-09
CA1339314C (en) 1997-08-19
NZ230672A (en) 1990-12-21
US5077295A (en) 1991-12-31
FI911285A0 (fi) 1991-03-15
ATE92063T1 (de) 1993-08-15
AU4150689A (en) 1990-03-22
IE892949L (en) 1990-03-16
DE68907845T2 (de) 1993-11-11

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees