IL91216A - חומצה )r5, s6( -2- קרבאמואילוקסימתיל-r)] -16(- הידרוקסיאתיל[-2- פנם- קרבוקסילית גבישית ותכשירי רוקחות המכילים אותה - Google Patents
חומצה )r5, s6( -2- קרבאמואילוקסימתיל-r)] -16(- הידרוקסיאתיל[-2- פנם- קרבוקסילית גבישית ותכשירי רוקחות המכילים אותהInfo
- Publication number
- IL91216A IL91216A IL9121689A IL9121689A IL91216A IL 91216 A IL91216 A IL 91216A IL 9121689 A IL9121689 A IL 9121689A IL 9121689 A IL9121689 A IL 9121689A IL 91216 A IL91216 A IL 91216A
- Authority
- IL
- Israel
- Prior art keywords
- penem
- hydroxyethyl
- carboxylic acid
- crystalline
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888818789A GB8818789D0 (en) | 1988-08-08 | 1988-08-08 | Crystalline(5r 6s)-2-carbamoyloxymethyl-6-((1r)-hydroxyethyl)-2-penem-carboxylic acid & pharmaceutical formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL91216A0 IL91216A0 (en) | 1990-03-19 |
| IL91216A true IL91216A (he) | 1994-10-21 |
Family
ID=10641768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9121689A IL91216A (he) | 1988-08-08 | 1989-08-04 | חומצה )r5, s6( -2- קרבאמואילוקסימתיל-r)] -16(- הידרוקסיאתיל[-2- פנם- קרבוקסילית גבישית ותכשירי רוקחות המכילים אותה |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5302588A (he) |
| EP (1) | EP0407478B1 (he) |
| JP (1) | JP2954956B2 (he) |
| KR (1) | KR900701799A (he) |
| AT (1) | ATE112777T1 (he) |
| AU (1) | AU626576B2 (he) |
| CA (1) | CA1339422C (he) |
| DE (1) | DE68918849T2 (he) |
| DK (1) | DK171235B1 (he) |
| ES (1) | ES2015770A6 (he) |
| FI (1) | FI95575C (he) |
| GB (1) | GB8818789D0 (he) |
| GR (1) | GR1002251B (he) |
| HU (1) | HU205934B (he) |
| IE (1) | IE68447B1 (he) |
| IL (1) | IL91216A (he) |
| NZ (1) | NZ230196A (he) |
| PT (1) | PT91383B (he) |
| RU (1) | RU2074858C1 (he) |
| WO (1) | WO1990001484A1 (he) |
| ZA (1) | ZA895966B (he) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5492903A (en) * | 1990-06-19 | 1996-02-20 | Takeda Chemical Industries Ltd. | Crystalline esters of (+)-(5R, 6S)-6-[(R)-1-hydroxyethyl]-3-(3-pyridyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]he |
| US20090275746A1 (en) * | 2006-07-28 | 2009-11-05 | Hetero Drugs Limited | Solid faropenem free acid |
| KR20160109904A (ko) * | 2015-03-13 | 2016-09-21 | 주식회사 대웅제약 | 결정형 도리페넴의 제조방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4482565A (en) * | 1980-02-22 | 1984-11-13 | Farmitalia Carlo Erba S.P.A. | β-Lactam-containing antibacterial agents and β-lactamase inhibitors |
| US4508649A (en) * | 1981-12-11 | 1985-04-02 | Farmitalia Carlo Erba | Process for preparing optically active penems |
| US4761408A (en) * | 1984-11-02 | 1988-08-02 | Ciba-Geigy Corporation | Crystalline aminomethyl compound |
| US4634556A (en) * | 1985-05-10 | 1987-01-06 | Schering Corporation | Crystalline sodium (5R, 6S, 8R)-6-(1-hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylate and process for making same |
| PT84767B (en) * | 1986-04-29 | 1989-06-09 | Ciba Geigy Ag | Process for preparing a crystalline (5r.6s)-2-aminomethyl-6-](1r)-1-hydroxyethyl"-2-penem-3-carboxylic acid hydrate |
| GB8915392D0 (en) * | 1989-07-05 | 1989-08-23 | Erba Carlo Spa | Process for penems |
-
1988
- 1988-08-08 GB GB888818789A patent/GB8818789D0/en active Pending
-
1989
- 1989-08-03 NZ NZ230196A patent/NZ230196A/xx unknown
- 1989-08-03 GR GR890100493A patent/GR1002251B/el unknown
- 1989-08-04 IL IL9121689A patent/IL91216A/he not_active IP Right Cessation
- 1989-08-04 RU SU894743591A patent/RU2074858C1/ru active
- 1989-08-04 ES ES898902797A patent/ES2015770A6/es not_active Expired - Lifetime
- 1989-08-04 DE DE68918849T patent/DE68918849T2/de not_active Expired - Fee Related
- 1989-08-04 PT PT91383A patent/PT91383B/pt not_active IP Right Cessation
- 1989-08-04 IE IE252889A patent/IE68447B1/en not_active IP Right Cessation
- 1989-08-04 EP EP89908980A patent/EP0407478B1/en not_active Expired - Lifetime
- 1989-08-04 WO PCT/EP1989/000924 patent/WO1990001484A1/en active IP Right Grant
- 1989-08-04 KR KR1019900700723A patent/KR900701799A/ko not_active Application Discontinuation
- 1989-08-04 HU HU894594A patent/HU205934B/hu not_active IP Right Cessation
- 1989-08-04 AT AT89908980T patent/ATE112777T1/de active
- 1989-08-04 JP JP1508464A patent/JP2954956B2/ja not_active Expired - Fee Related
- 1989-08-04 AU AU40490/89A patent/AU626576B2/en not_active Ceased
- 1989-08-04 ZA ZA895966A patent/ZA895966B/xx unknown
- 1989-08-04 CA CA000607546A patent/CA1339422C/en not_active Expired - Fee Related
-
1990
- 1990-04-04 FI FI901710A patent/FI95575C/fi not_active IP Right Cessation
- 1990-04-05 DK DK085490A patent/DK171235B1/da not_active IP Right Cessation
-
1992
- 1992-06-16 US US07/899,057 patent/US5302588A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HU205934B (en) | 1992-07-28 |
| HUT56571A (en) | 1991-09-30 |
| PT91383A (pt) | 1990-03-08 |
| JPH03500781A (ja) | 1991-02-21 |
| US5302588A (en) | 1994-04-12 |
| DK85490A (da) | 1990-06-07 |
| FI95575B (fi) | 1995-11-15 |
| JP2954956B2 (ja) | 1999-09-27 |
| KR900701799A (ko) | 1990-12-04 |
| FI901710A0 (fi) | 1990-04-04 |
| DK171235B1 (da) | 1996-08-05 |
| FI95575C (fi) | 1996-02-26 |
| ES2015770A6 (es) | 1990-09-01 |
| GR1002251B (en) | 1996-04-23 |
| DK85490D0 (da) | 1990-04-05 |
| IE68447B1 (en) | 1996-06-26 |
| DE68918849D1 (de) | 1994-11-17 |
| IL91216A0 (en) | 1990-03-19 |
| EP0407478A1 (en) | 1991-01-16 |
| ATE112777T1 (de) | 1994-10-15 |
| AU4049089A (en) | 1990-03-05 |
| PT91383B (pt) | 1995-05-31 |
| GR890100493A (el) | 1990-08-22 |
| GB8818789D0 (en) | 1988-09-07 |
| IE892528L (en) | 1990-02-08 |
| RU2074858C1 (ru) | 1997-03-10 |
| ZA895966B (en) | 1990-06-27 |
| WO1990001484A1 (en) | 1990-02-22 |
| DE68918849T2 (de) | 1995-02-23 |
| NZ230196A (en) | 1990-09-26 |
| CA1339422C (en) | 1997-09-02 |
| HU894594D0 (en) | 1991-07-29 |
| AU626576B2 (en) | 1992-08-06 |
| EP0407478B1 (en) | 1994-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |