IL91188A - Biocompatible substances with hydrodin stationary for the production of prostheses to prevent blood clotting - Google Patents

Biocompatible substances with hydrodin stationary for the production of prostheses to prevent blood clotting

Info

Publication number
IL91188A
IL91188A IL9118889A IL9118889A IL91188A IL 91188 A IL91188 A IL 91188A IL 9118889 A IL9118889 A IL 9118889A IL 9118889 A IL9118889 A IL 9118889A IL 91188 A IL91188 A IL 91188A
Authority
IL
Israel
Prior art keywords
base coat
inhibitor
coat layer
thrombogenesis
reagent
Prior art date
Application number
IL9118889A
Other languages
English (en)
Hebrew (he)
Other versions
IL91188A0 (en
Original Assignee
New England Deaconess Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New England Deaconess Hospital filed Critical New England Deaconess Hospital
Publication of IL91188A0 publication Critical patent/IL91188A0/xx
Publication of IL91188A publication Critical patent/IL91188A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/14—Post-treatment to improve physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/12—Polypeptides, proteins or derivatives thereof, e.g. degradation products thereof
    • A61L33/128—Other specific proteins or polypeptides not covered by A61L33/122 - A61L33/126
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
IL9118889A 1988-08-03 1989-08-02 Biocompatible substances with hydrodin stationary for the production of prostheses to prevent blood clotting IL91188A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/227,700 US5167960A (en) 1988-08-03 1988-08-03 Hirudin-coated biocompatible substance

Publications (2)

Publication Number Publication Date
IL91188A0 IL91188A0 (en) 1990-03-19
IL91188A true IL91188A (en) 1994-02-27

Family

ID=22854125

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9118889A IL91188A (en) 1988-08-03 1989-08-02 Biocompatible substances with hydrodin stationary for the production of prostheses to prevent blood clotting

Country Status (17)

Country Link
US (1) US5167960A (de)
EP (1) EP0357242B1 (de)
JP (1) JPH02147067A (de)
KR (1) KR900002752A (de)
AT (1) ATE117212T1 (de)
AU (1) AU624170B2 (de)
CA (1) CA1338756C (de)
DD (1) DD283933A5 (de)
DE (1) DE68920671T2 (de)
DK (1) DK379189A (de)
ES (1) ES2068897T3 (de)
FI (1) FI893660A (de)
IE (1) IE892501L (de)
IL (1) IL91188A (de)
NZ (1) NZ230180A (de)
PT (1) PT91345A (de)
ZA (1) ZA895862B (de)

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US5262451A (en) * 1988-06-08 1993-11-16 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
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US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
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US5837808A (en) * 1991-08-20 1998-11-17 Baxter International Inc. Analogs of hirudin
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US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
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ATE244584T1 (de) * 1995-01-16 2003-07-15 Baxter Int Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen
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US5900433A (en) * 1995-06-23 1999-05-04 Cormedics Corp. Vascular treatment method and apparatus
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DE69636289T2 (de) 1995-12-18 2007-05-10 Angiodevice International Gmbh Vernetzten polymerisatmassen und verfahren für ihre verwendung
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US7883693B2 (en) 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
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US6702851B1 (en) 1996-09-06 2004-03-09 Joseph A. Chinn Prosthetic heart valve with surface modification
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US5891196A (en) * 1997-04-16 1999-04-06 Baxter International Inc. Method for actively binding heparin to crosslinked biological tissues
US5879697A (en) * 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
US20050124608A1 (en) * 2001-04-03 2005-06-09 Redmond H. P. Treatment of cancers
US8304390B2 (en) * 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
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US6221425B1 (en) 1998-01-30 2001-04-24 Advanced Cardiovascular Systems, Inc. Lubricious hydrophilic coating for an intracorporeal medical device
US6419643B1 (en) 1998-04-21 2002-07-16 Alsius Corporation Central venous catheter with heat exchange properties
US6530946B1 (en) 1998-04-21 2003-03-11 Alsius Corporation Indwelling heat exchange heat pipe catheter and method of using same
US6126684A (en) * 1998-04-21 2000-10-03 The Regents Of The University Of California Indwelling heat exchange catheter and method of using same
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US6582398B1 (en) * 1999-02-19 2003-06-24 Alsius Corporation Method of managing patient temperature with a heat exchange catheter
US7892530B2 (en) * 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US8030301B2 (en) * 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US7345039B2 (en) * 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
US6572640B1 (en) 2001-11-21 2003-06-03 Alsius Corporation Method and apparatus for cardiopulmonary bypass patient temperature control
EP2311479B1 (de) * 2002-09-20 2014-07-23 The Trustees of The University of Pennsylvania Compstatin-Analoga mit verbesserter Aktivität
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Also Published As

Publication number Publication date
DE68920671T2 (de) 1995-07-06
ZA895862B (en) 1990-05-30
EP0357242A1 (de) 1990-03-07
FI893660A (fi) 1990-02-04
KR900002752A (ko) 1990-03-23
JPH02147067A (ja) 1990-06-06
IL91188A0 (en) 1990-03-19
DK379189A (da) 1990-02-04
PT91345A (pt) 1990-03-08
NZ230180A (en) 1991-02-26
FI893660A0 (fi) 1989-08-02
DD283933A5 (de) 1990-10-31
ES2068897T3 (es) 1995-05-01
AU624170B2 (en) 1992-06-04
ATE117212T1 (de) 1995-02-15
AU3918889A (en) 1990-02-08
CA1338756C (en) 1996-12-03
DE68920671D1 (de) 1995-03-02
EP0357242B1 (de) 1995-01-18
US5167960A (en) 1992-12-01
IE892501L (en) 1990-02-03
DK379189D0 (da) 1989-08-02

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