IL90908A0 - Derivatives of 1-hydroxy-2-piperidylalkyl-indol-2-ones-2-quinolinones,2-benzo(b)azepinones,benzimidazol-2-ones,and quinazolin-2-ones,their preparation and their application in therapeutics - Google Patents
Derivatives of 1-hydroxy-2-piperidylalkyl-indol-2-ones-2-quinolinones,2-benzo(b)azepinones,benzimidazol-2-ones,and quinazolin-2-ones,their preparation and their application in therapeuticsInfo
- Publication number
- IL90908A0 IL90908A0 IL90908A IL9090889A IL90908A0 IL 90908 A0 IL90908 A0 IL 90908A0 IL 90908 A IL90908 A IL 90908A IL 9090889 A IL9090889 A IL 9090889A IL 90908 A0 IL90908 A0 IL 90908A0
- Authority
- IL
- Israel
- Prior art keywords
- group
- ones
- denotes
- optionally substituted
- application
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8809449A FR2634206B1 (fr) | 1988-07-12 | 1988-07-12 | Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2 et quinoleinones-2, leur preparation et leur application en therapeutique |
FR888816373A FR2640266B2 (fr) | 1988-07-12 | 1988-12-13 | Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
IL90908A0 true IL90908A0 (en) | 1990-02-09 |
Family
ID=26226791
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL90908A IL90908A0 (en) | 1988-07-12 | 1989-07-10 | Derivatives of 1-hydroxy-2-piperidylalkyl-indol-2-ones-2-quinolinones,2-benzo(b)azepinones,benzimidazol-2-ones,and quinazolin-2-ones,their preparation and their application in therapeutics |
Country Status (18)
Country | Link |
---|---|
US (1) | US5034401A (hu) |
EP (1) | EP0351282B1 (hu) |
JP (1) | JPH0272173A (hu) |
KR (1) | KR900001684A (hu) |
AT (1) | ATE96437T1 (hu) |
AU (1) | AU618378B2 (hu) |
CA (1) | CA1317292C (hu) |
DE (1) | DE68910210T2 (hu) |
DK (1) | DK341989A (hu) |
ES (1) | ES2062064T3 (hu) |
FI (1) | FI93012C (hu) |
FR (1) | FR2640266B2 (hu) |
HU (1) | HU201544B (hu) |
IE (1) | IE62216B1 (hu) |
IL (1) | IL90908A0 (hu) |
NO (1) | NO174100C (hu) |
NZ (1) | NZ229903A (hu) |
PT (1) | PT91126B (hu) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5182278A (en) * | 1989-02-28 | 1993-01-26 | Adir Et Compagnie | Analgesic benzoxazolinones having at the 6-position a 1-hydroxy-3-morpholinopropyl side chain |
CA2023492A1 (en) * | 1989-08-31 | 1991-03-01 | Barry Clifford Lange | Herbicidal glutarimides |
BR9106432A (pt) * | 1990-05-10 | 1993-05-04 | Pfizer | Indolona neuroprotetora e derivados correlatos |
JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
FR2668149B1 (fr) * | 1990-10-18 | 1994-09-23 | Synthelabo | Le 1-(3,4-dihydro-2-oxo-1h-quinolein-6-yl)-2-[4-(2-phenyl-ethyl)piperidin-1-yl]ethanol, sa preparation et son application en therapeutique. |
TW197435B (hu) * | 1990-11-22 | 1993-01-01 | Takeda Pharm Industry Co Ltd | |
NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
EP0524846A1 (fr) * | 1991-06-27 | 1993-01-27 | Synthelabo | Dérivés de 2-(pipéridin-1-y1) éthanol, leur préparation et leur application en thérapeutique |
FR2678270B1 (fr) * | 1991-06-27 | 1995-01-13 | Synthelabo | Derives de 2-(piperidin-1-yl)ethanol, leur preparation et leur application en therapeutique. |
AU655840B2 (en) * | 1991-07-17 | 1995-01-12 | Pfizer Inc. | 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents |
TW263504B (hu) * | 1991-10-03 | 1995-11-21 | Pfizer | |
FR2684379B1 (fr) * | 1991-12-02 | 1995-04-28 | Synthelabo | Derives de piperidine, leur preparation et leur application en therapeutique. |
US5462934A (en) * | 1992-03-09 | 1995-10-31 | Takeda Chemical Industries | Condensed heterocyclic ketone derivatives and their use |
TW218875B (hu) * | 1992-03-09 | 1994-01-11 | Takeda Pharm Industry Co Ltd | |
FR2688504B1 (fr) * | 1992-03-13 | 1995-05-05 | Synthelabo | Derives de 2-(piperidin-1-yl)ethanol, leur preparation et leur application en therapeutique. |
US6255322B1 (en) | 1992-06-19 | 2001-07-03 | Pfizer Inc. | 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents |
US5436255A (en) * | 1992-07-23 | 1995-07-25 | Pfizer Inc. | Method of treating diseases susceptable to treatment by blocking NMDA-receptors |
WO1994010166A1 (en) * | 1992-10-30 | 1994-05-11 | Pfizer Inc. | Neuroprotective 3,4-dihydro-2(1h)-quinolone compounds |
US5498610A (en) * | 1992-11-06 | 1996-03-12 | Pfizer Inc. | Neuroprotective indolone and related derivatives |
CA2182101C (en) * | 1994-01-31 | 1999-08-03 | Todd W. Butler | Neuroprotective compounds |
EP0709384B1 (de) * | 1994-10-31 | 1998-12-23 | MERCK PATENT GmbH | Benzylpiperidinderivate mit hoher Affinität zu Bindungsstellen von Aminosäure-Rezeptoren |
KR19990044479A (ko) * | 1995-09-08 | 1999-06-25 | 에.뚜레 레메뜨르 | 4-(시클로알킬)피페리딘 유도체와 4-(시클로알킬알킬)피페리딘유도체,그것들의 제법 및 치료학적 사용 |
FR2738568B1 (fr) * | 1995-09-08 | 1997-10-17 | Synthelabo | Derives de 4-(cycloalkyl)piperidines et 4-(cycloalkylalkyl) piperidines, leur preparation et leur application en therapeutique |
ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
ZA9610736B (en) | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
ZA9610741B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
NZ503626A (en) * | 1997-11-05 | 2002-05-31 | Neurosearch As | Azaring-ether derivatives and their use as nicotinic ACh receptor modulators |
GB9725541D0 (en) * | 1997-12-02 | 1998-02-04 | Pharmacia & Upjohn Spa | Amino-benzothiazole derivatives |
AR033485A1 (es) * | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma |
ES2691671T3 (es) | 2010-06-24 | 2018-11-28 | Alkermes Pharma Ireland Limited | Profármacos de compuestos NH-acídicos: derivados de éster, carbonato, carbamato y fosfonato |
MA41169A (fr) * | 2014-12-17 | 2017-10-24 | Acraf | Composés antibactériens à large spectre d'activité |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3217011A (en) * | 1965-05-07 | 1965-11-09 | Sterling Drug Inc | 1-(indolyglyoxalyl)-piperidines |
JPS51125291A (en) * | 1974-12-07 | 1976-11-01 | Otsuka Pharmaceut Co Ltd | A process for preparing novel carbostyryl derivatives |
JPS51118772A (en) * | 1975-04-09 | 1976-10-18 | Otsuka Pharmaceut Co Ltd | Method for preparing carbostyryl derivatives |
PH17194A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives,and pharmaceutical composition containing the same |
FR2528043A1 (fr) * | 1982-06-03 | 1983-12-09 | Roussel Uclaf | Nouveaux derives de la 1,3-dihydro 4-/1-hydroxy-2-amino-ethyl/2h-indol-2-one, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
FR2581993B1 (fr) * | 1985-05-14 | 1988-03-18 | Synthelabo | Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique |
US4788201A (en) * | 1987-01-22 | 1988-11-29 | Hoechst-Roussel Pharmaceuticals Inc. | 3-methylenespiro (benzofuranpiperidines) |
-
1988
- 1988-12-13 FR FR888816373A patent/FR2640266B2/fr not_active Expired - Lifetime
-
1989
- 1989-07-03 DE DE89401898T patent/DE68910210T2/de not_active Expired - Fee Related
- 1989-07-03 AT AT89401898T patent/ATE96437T1/de not_active IP Right Cessation
- 1989-07-03 EP EP89401898A patent/EP0351282B1/fr not_active Expired - Lifetime
- 1989-07-03 ES ES89401898T patent/ES2062064T3/es not_active Expired - Lifetime
- 1989-07-10 IL IL90908A patent/IL90908A0/xx not_active IP Right Cessation
- 1989-07-11 HU HU893488A patent/HU201544B/hu not_active IP Right Cessation
- 1989-07-11 JP JP1180140A patent/JPH0272173A/ja active Pending
- 1989-07-11 US US07/378,094 patent/US5034401A/en not_active Expired - Lifetime
- 1989-07-11 PT PT91126A patent/PT91126B/pt active IP Right Grant
- 1989-07-11 NO NO892870A patent/NO174100C/no not_active IP Right Cessation
- 1989-07-11 CA CA000605386A patent/CA1317292C/en not_active Expired - Fee Related
- 1989-07-11 KR KR1019890009861A patent/KR900001684A/ko not_active Application Discontinuation
- 1989-07-11 FI FI893365A patent/FI93012C/fi not_active IP Right Cessation
- 1989-07-11 NZ NZ229903A patent/NZ229903A/en unknown
- 1989-07-11 AU AU38029/89A patent/AU618378B2/en not_active Ceased
- 1989-07-11 DK DK341989A patent/DK341989A/da not_active Application Discontinuation
- 1989-07-11 IE IE223789A patent/IE62216B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA1317292C (en) | 1993-05-04 |
NO892870L (no) | 1990-01-15 |
NO174100B (no) | 1993-12-06 |
PT91126A (pt) | 1990-02-08 |
IE62216B1 (en) | 1995-01-11 |
US5034401A (en) | 1991-07-23 |
FI893365A (fi) | 1990-01-13 |
FI93012B (fi) | 1994-10-31 |
NO174100C (no) | 1994-03-16 |
AU3802989A (en) | 1990-01-18 |
DE68910210T2 (de) | 1994-05-11 |
FR2640266B2 (fr) | 1992-07-10 |
EP0351282B1 (fr) | 1993-10-27 |
DK341989A (da) | 1990-04-25 |
NZ229903A (en) | 1991-04-26 |
ATE96437T1 (de) | 1993-11-15 |
FR2640266A2 (fr) | 1990-06-15 |
HU201544B (en) | 1990-11-28 |
NO892870D0 (no) | 1989-07-11 |
EP0351282A1 (fr) | 1990-01-17 |
FI893365A0 (fi) | 1989-07-11 |
FI93012C (fi) | 1995-02-10 |
PT91126B (pt) | 1994-12-30 |
JPH0272173A (ja) | 1990-03-12 |
DE68910210D1 (de) | 1993-12-02 |
AU618378B2 (en) | 1991-12-19 |
IE892237L (en) | 1990-01-12 |
ES2062064T3 (es) | 1994-12-16 |
DK341989D0 (da) | 1989-07-11 |
KR900001684A (ko) | 1990-02-27 |
HUT50328A (en) | 1990-01-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |