FR2738568B1 - Derives de 4-(cycloalkyl)piperidines et 4-(cycloalkylalkyl) piperidines, leur preparation et leur application en therapeutique - Google Patents

Derives de 4-(cycloalkyl)piperidines et 4-(cycloalkylalkyl) piperidines, leur preparation et leur application en therapeutique

Info

Publication number
FR2738568B1
FR2738568B1 FR9510512A FR9510512A FR2738568B1 FR 2738568 B1 FR2738568 B1 FR 2738568B1 FR 9510512 A FR9510512 A FR 9510512A FR 9510512 A FR9510512 A FR 9510512A FR 2738568 B1 FR2738568 B1 FR 2738568B1
Authority
FR
France
Prior art keywords
piperidines
cycloalkylalkyl
cycloalkyl
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9510512A
Other languages
English (en)
Other versions
FR2738568A1 (fr
Inventor
Patrick Lardenois
Jonathan Frost
Patrick Pasau
Pascal George
Maria Carmen Renones
Regine Bartsch
Wai Tak Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9510512A priority Critical patent/FR2738568B1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to CZ98665A priority patent/CZ66598A3/cs
Priority to DE69603613T priority patent/DE69603613T2/de
Priority to BR9610408A priority patent/BR9610408A/pt
Priority to EE9800064A priority patent/EE9800064A/xx
Priority to NZ316981A priority patent/NZ316981A/xx
Priority to KR1019980701727A priority patent/KR19990044479A/ko
Priority to SK311-98A priority patent/SK31198A3/sk
Priority to TR1998/00407T priority patent/TR199800407T1/xx
Priority to PL96325421A priority patent/PL325421A1/xx
Priority to JP9510910A priority patent/JPH11514975A/ja
Priority to IL12355796A priority patent/IL123557A0/xx
Priority to EP96930216A priority patent/EP0848707B1/fr
Priority to PCT/FR1996/001362 priority patent/WO1997009309A1/fr
Priority to SI9630106T priority patent/SI0848707T1/xx
Priority to CO96047348A priority patent/CO4750660A1/es
Priority to ES96930216T priority patent/ES2137015T3/es
Priority to HU9802938A priority patent/HUP9802938A2/hu
Priority to AT96930216T priority patent/ATE182885T1/de
Priority to CA002231326A priority patent/CA2231326A1/fr
Priority to CN96198170A priority patent/CN1201453A/zh
Priority to AU69344/96A priority patent/AU703776B2/en
Priority to ARP960104270A priority patent/AR003530A1/es
Publication of FR2738568A1 publication Critical patent/FR2738568A1/fr
Publication of FR2738568B1 publication Critical patent/FR2738568B1/fr
Application granted granted Critical
Priority to BG102282A priority patent/BG102282A/xx
Priority to MXPA/A/1998/001838A priority patent/MXPA98001838A/xx
Priority to NO981000A priority patent/NO981000L/no
Priority to GR990402608T priority patent/GR3031513T3/el
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR9510512A 1995-09-08 1995-09-08 Derives de 4-(cycloalkyl)piperidines et 4-(cycloalkylalkyl) piperidines, leur preparation et leur application en therapeutique Expired - Fee Related FR2738568B1 (fr)

Priority Applications (27)

Application Number Priority Date Filing Date Title
FR9510512A FR2738568B1 (fr) 1995-09-08 1995-09-08 Derives de 4-(cycloalkyl)piperidines et 4-(cycloalkylalkyl) piperidines, leur preparation et leur application en therapeutique
HU9802938A HUP9802938A2 (hu) 1995-09-08 1996-09-05 4-Cikloalkil-piperidin és 4-cikloalkil-alkil-piperidin-származékok, eljárás a vegyületek előállítására és a vegyületek alkalmazása a gyógyászatban
CO96047348A CO4750660A1 (es) 1995-09-08 1996-09-05 Derivados de 4(cicloalquil) piperidinas y de 4-(cicloalquil- alquil) piperidinas, su preparacion y su aplicacion en tera- peutica
EE9800064A EE9800064A (et) 1995-09-08 1996-09-05 4-(tsükloalküül)piperidiinide ja 4-(tsükloalküülalküül)piperidiinide derivaadid, nende valmistamine ja terapeutiline kasutamine
NZ316981A NZ316981A (en) 1995-09-08 1996-09-05 4-(cycloalkyl)piperidine and 4-(cycloalkylalkyl)piperidine derivatives, preparation thereof and therapeutical applications thereof
KR1019980701727A KR19990044479A (ko) 1995-09-08 1996-09-05 4-(시클로알킬)피페리딘 유도체와 4-(시클로알킬알킬)피페리딘유도체,그것들의 제법 및 치료학적 사용
SK311-98A SK31198A3 (en) 1995-09-08 1996-09-05 4-(cycloalkyl)piperidine and 4-(cycloalkylalkyl)piperidine derivatives, preparation thereof and therapeutical applications thereof
TR1998/00407T TR199800407T1 (xx) 1995-09-08 1996-09-05 4-(Sikloalkil) piperidin ve t�revleri, haz�rlan��lar�, tedavi ama�l� kullan�mlar�.
PL96325421A PL325421A1 (en) 1995-09-08 1996-09-05 Derivatives of 4-(cycloalkyl) piperidines and 4-(cycloalkylallyl) piperidines, method for obtaining them and their therapeutic application
JP9510910A JPH11514975A (ja) 1995-09-08 1996-09-05 ４−（シクロアルキル）ピペリジンおよび４−（シクロアルキルアルキル）ピペリジン誘導体、その製造、並びにその治療上の利用
IL12355796A IL123557A0 (en) 1995-09-08 1996-09-05 Derivatives of 4-(cycloalkyl) piperidines and of 4-(cycloalkylalkyl) piperidines their preparation and their therapeutic application
DE69603613T DE69603613T2 (de) 1995-09-08 1996-09-05 4-(cycloalkyl)piperidine und 4-(cycloalkylalkyl)-piperidine, ihre herstellung und therapeutische verwendung
PCT/FR1996/001362 WO1997009309A1 (fr) 1995-09-08 1996-09-05 Derives de 4-(cycloalkyl)piperidines et de 4-(cycloalkylalkyl)pi peridines, leur preparation et leur application en therapeutique
SI9630106T SI0848707T1 (en) 1995-09-08 1996-09-05 4-(cycloalkyl)piperidines and 4-(cycloalkylalkyl)-piperidines derivatives, preparation thereof and therapeutical applications thereof
CZ98665A CZ66598A3 (cs) 1995-09-08 1996-09-05 Deriváty 4-(cykloalkyl)piperidinů a 4-(cykloalkylalkyl)-piperidinů, způsob jejich přípravy a léčivo, které je obsahuje
BR9610408A BR9610408A (pt) 1995-09-08 1996-09-05 Derivados de 4-(cicloalquil) piperidinas e de 4-(cicloalquilalquil) piperidinas preparação dos memos e aplicação terapêutica dos mesmos
ES96930216T ES2137015T3 (es) 1995-09-08 1996-09-05 Compuesto, eventualmente bajo la forma de un isomero puro o de una mezla de estos isomeros.
AT96930216T ATE182885T1 (de) 1995-09-08 1996-09-05 4-(cycloalkyl)piperidine und 4-(cycloalkylalkyl)- piperidine, ihre herstellung und therapeutische verwendung
CA002231326A CA2231326A1 (fr) 1995-09-08 1996-09-05 Derives de 4-(cycloalkyl)piperidines et de 4-(cycloalkylalkyl)pi peridines, leur preparation et leur application en therapeutique
CN96198170A CN1201453A (zh) 1995-09-08 1996-09-05 4－(环烷基)－哌啶和4－(环烷基烷基)哌啶衍生物,其制备方法及其在药物中的应用
AU69344/96A AU703776B2 (en) 1995-09-08 1996-09-05 Derivatives of 4-(cycloalkyl)piperidines and of 4-(cycloalkylalkyl)piperidines, their preparation and their therapeutic application
EP96930216A EP0848707B1 (fr) 1995-09-08 1996-09-05 Derives de 4-(cycloalkyl)piperidines et de 4-(cycloalkylalkyl)pi peridines, leur preparation et leur application en therapeutique
ARP960104270A AR003530A1 (es) 1995-09-08 1996-09-06 Derivados de 4-(cicloalquil) piperidinas y de 4-(ciclo alquil alquil) piperidinas, procedimiento para su preparacion y composiciones farmaceuticasque los contienen.
BG102282A BG102282A (en) 1995-09-08 1998-02-26 Derivatives of 4-(cycloalkyl) piperidines and 4-(cycloalkylalkyl) piperidines, their preparation and application in medicine
MXPA/A/1998/001838A MXPA98001838A (en) 1995-09-08 1998-03-06 Derivatives of 4- (cicloalquil) piperidinas and of 4- (cicloalquilalquil) piperidinas, its preparation and its application terapeut
NO981000A NO981000L (no) 1995-09-08 1998-03-06 4-(cykloalkyl)piperidin og 4-(cykloalkylalkyl)piperidin derivater, deres fremstilling og terapeutiske anvendelse
GR990402608T GR3031513T3 (en) 1995-09-08 1999-10-13 4-(cycloalkyl)piperidines and 4-(cycloalkylalkyl)-piperidines derivatives, preparation thereof and therapeutical applications thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9510512A FR2738568B1 (fr) 1995-09-08 1995-09-08 Derives de 4-(cycloalkyl)piperidines et 4-(cycloalkylalkyl) piperidines, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2738568A1 FR2738568A1 (fr) 1997-03-14
FR2738568B1 true FR2738568B1 (fr) 1997-10-17

Family

ID=9482364

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9510512A Expired - Fee Related FR2738568B1 (fr) 1995-09-08 1995-09-08 Derives de 4-(cycloalkyl)piperidines et 4-(cycloalkylalkyl) piperidines, leur preparation et leur application en therapeutique

Country Status (1)

Country Link
FR (1) FR2738568B1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0994709A4 (fr) 1997-06-30 2006-02-01 Allergan Inc Antagonistes du calcium servant a traiter la vitreoretinopathie proliferative
WO1999025350A1 (fr) * 1997-11-14 1999-05-27 Alcon Laboratories, Inc. Traitement de la retinopathie diabetique

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261891A (en) * 1965-08-24 1981-04-14 Ciba-Geigy Corporation Antibiotically active rifamycin derivatives
US4005093A (en) * 1975-01-20 1977-01-25 Sterling Drug Inc. 2-Naphthyl-lower-alkylamines
US4028366A (en) * 1975-01-20 1977-06-07 Sterling Drug Inc. 2-Naphthyl-lower-alkanoylamines
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
FR2684379B1 (fr) * 1991-12-02 1995-04-28 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
FR2738568A1 (fr) 1997-03-14

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