NO981000L - 4-(cykloalkyl)piperidin og 4-(cykloalkylalkyl)piperidin derivater, deres fremstilling og terapeutiske anvendelse - Google Patents

4-(cykloalkyl)piperidin og 4-(cykloalkylalkyl)piperidin derivater, deres fremstilling og terapeutiske anvendelse

Info

Publication number
NO981000L
NO981000L NO981000A NO981000A NO981000L NO 981000 L NO981000 L NO 981000L NO 981000 A NO981000 A NO 981000A NO 981000 A NO981000 A NO 981000A NO 981000 L NO981000 L NO 981000L
Authority
NO
Norway
Prior art keywords
piperidine
group
cycloalkyl
therapeutic use
cycloalkylalkyl
Prior art date
Application number
NO981000A
Other languages
English (en)
Other versions
NO981000D0 (no
Inventor
Patrick Lardenois
Jonathan Frost
Patrick Pasau
Pascal George
Maria-Carmen Renones
Rugine Bartsch
Wai-Tak Li
Pascale Magat
Rugis Dupont
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9510512A external-priority patent/FR2738568B1/fr
Priority claimed from FR9510513A external-priority patent/FR2738566B1/fr
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO981000D0 publication Critical patent/NO981000D0/no
Publication of NO981000L publication Critical patent/NO981000L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Forbindelser med generell formel (I) (D hvor Ar er (a) en fenylgruppe substituert med et halogenatom eller (b) en gruppe med generell formel (I1) (I1) hvor X er en gruppe med formel -CH2-, -(CH2)2- eller -(CH2)3- og Z er et hydrogen- eller halogenatom eller en metylgruppe, Y er en gruppe med formel -CH2-, -CO- eller -CHOH-, Rx er et hydrogenatom eller en metylgruppe, R2 er en C3-C7 cykloalkylgruppe og n er O, I, 2 eller 3. De nevnte forbindelser har terapeutisk anvendelse som nevrotrofiske og nevrobeskyttende midler.
NO981000A 1995-09-08 1998-03-06 4-(cykloalkyl)piperidin og 4-(cykloalkylalkyl)piperidin derivater, deres fremstilling og terapeutiske anvendelse NO981000L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9510512A FR2738568B1 (fr) 1995-09-08 1995-09-08 Derives de 4-(cycloalkyl)piperidines et 4-(cycloalkylalkyl) piperidines, leur preparation et leur application en therapeutique
FR9510513A FR2738566B1 (fr) 1995-09-08 1995-09-08 Derives de 4-(cycloalkyl)piperidines et de 4-(cycloalkylalkyl)piperidines, leur preparation et leur application en therapeutique
PCT/FR1996/001362 WO1997009309A1 (fr) 1995-09-08 1996-09-05 Derives de 4-(cycloalkyl)piperidines et de 4-(cycloalkylalkyl)pi peridines, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
NO981000D0 NO981000D0 (no) 1998-03-06
NO981000L true NO981000L (no) 1998-05-08

Family

ID=26232195

Family Applications (1)

Application Number Title Priority Date Filing Date
NO981000A NO981000L (no) 1995-09-08 1998-03-06 4-(cykloalkyl)piperidin og 4-(cykloalkylalkyl)piperidin derivater, deres fremstilling og terapeutiske anvendelse

Country Status (25)

Country Link
EP (1) EP0848707B1 (no)
JP (1) JPH11514975A (no)
KR (1) KR19990044479A (no)
CN (1) CN1201453A (no)
AR (1) AR003530A1 (no)
AT (1) ATE182885T1 (no)
AU (1) AU703776B2 (no)
BG (1) BG102282A (no)
BR (1) BR9610408A (no)
CA (1) CA2231326A1 (no)
CO (1) CO4750660A1 (no)
CZ (1) CZ66598A3 (no)
DE (1) DE69603613T2 (no)
EE (1) EE9800064A (no)
ES (1) ES2137015T3 (no)
GR (1) GR3031513T3 (no)
HU (1) HUP9802938A2 (no)
IL (1) IL123557A0 (no)
NO (1) NO981000L (no)
NZ (1) NZ316981A (no)
PL (1) PL325421A1 (no)
SI (1) SI0848707T1 (no)
SK (1) SK31198A3 (no)
TR (1) TR199800407T1 (no)
WO (1) WO1997009309A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0994709A4 (en) 1997-06-30 2006-02-01 Allergan Inc CALCIUM BLOCKER FOR THE TREATMENT OF PROLIFERATIVE VITREORETINOPATHY
US6509355B1 (en) 1998-10-27 2003-01-21 Alcon Laboratories, Inc. Treatment of disorders of the outer retina
DK1755391T3 (en) * 2004-06-04 2016-02-08 Univ Washington METHODS AND COMPOSITIONS FOR THE TREATMENT OF neuropathies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028366A (en) * 1975-01-20 1977-06-07 Sterling Drug Inc. 2-Naphthyl-lower-alkanoylamines
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
FR2684379B1 (fr) * 1991-12-02 1995-04-28 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique.
WO1994018172A1 (en) * 1993-02-01 1994-08-18 Yoshitomi Pharmaceutical Industries, Ltd. Imidazolylbenzene compound and use thereof as medicine

Also Published As

Publication number Publication date
WO1997009309A1 (fr) 1997-03-13
GR3031513T3 (en) 2000-01-31
MX9801838A (es) 1998-08-30
PL325421A1 (en) 1998-07-20
IL123557A0 (en) 1998-10-30
AU703776B2 (en) 1999-04-01
BG102282A (en) 1998-09-30
CA2231326A1 (en) 1997-03-13
EE9800064A (et) 1998-08-17
EP0848707B1 (fr) 1999-08-04
DE69603613T2 (de) 2000-03-02
AR003530A1 (es) 1998-08-05
DE69603613D1 (de) 1999-09-09
AU6934496A (en) 1997-03-27
KR19990044479A (ko) 1999-06-25
CN1201453A (zh) 1998-12-09
CZ66598A3 (cs) 1998-06-17
CO4750660A1 (es) 1999-03-31
TR199800407T1 (xx) 1998-05-21
ES2137015T3 (es) 1999-12-01
HUP9802938A2 (hu) 1999-10-28
EP0848707A1 (fr) 1998-06-24
BR9610408A (pt) 1999-07-06
ATE182885T1 (de) 1999-08-15
SK31198A3 (en) 1998-08-05
JPH11514975A (ja) 1999-12-21
NZ316981A (en) 1998-12-23
NO981000D0 (no) 1998-03-06
SI0848707T1 (en) 2000-02-29

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NO981000L (no) 4-(cykloalkyl)piperidin og 4-(cykloalkylalkyl)piperidin derivater, deres fremstilling og terapeutiske anvendelse