ATE113943T1 - Bestimmte 3-substituierte 2-alkyl-benzofuran- derivate. - Google Patents

Bestimmte 3-substituierte 2-alkyl-benzofuran- derivate.

Info

Publication number
ATE113943T1
ATE113943T1 AT88910246T AT88910246T ATE113943T1 AT E113943 T1 ATE113943 T1 AT E113943T1 AT 88910246 T AT88910246 T AT 88910246T AT 88910246 T AT88910246 T AT 88910246T AT E113943 T1 ATE113943 T1 AT E113943T1
Authority
AT
Austria
Prior art keywords
substituted
alkyl
certain
methyl
hydrogen
Prior art date
Application number
AT88910246T
Other languages
English (en)
Inventor
Thomas P Kennedy
George W Kabalka
Original Assignee
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Application granted granted Critical
Publication of ATE113943T1 publication Critical patent/ATE113943T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT88910246T 1987-09-30 1988-09-28 Bestimmte 3-substituierte 2-alkyl-benzofuran- derivate. ATE113943T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/103,484 US4851554A (en) 1987-04-06 1987-09-30 Certain 3-substituted 2-alkyl benzofuran derivatives
CA000585726A CA1327794C (en) 1987-09-30 1988-12-13 Certain 3-substituted 2-alkyl benzofuran derivatives

Publications (1)

Publication Number Publication Date
ATE113943T1 true ATE113943T1 (de) 1994-11-15

Family

ID=25672297

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88910246T ATE113943T1 (de) 1987-09-30 1988-09-28 Bestimmte 3-substituierte 2-alkyl-benzofuran- derivate.

Country Status (8)

Country Link
US (1) US4851554A (de)
EP (1) EP0380588B1 (de)
JP (1) JP2509683B2 (de)
AT (1) ATE113943T1 (de)
AU (1) AU618303B2 (de)
CA (1) CA1327794C (de)
DE (1) DE3852107T2 (de)
WO (1) WO1989002892A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4975458A (en) * 1989-03-13 1990-12-04 Taro Pharmaceuticals Industries, Ltd. 2-alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
GB9416219D0 (en) * 1994-08-11 1994-10-05 Karobio Ab Receptor ligands
US6703407B1 (en) * 1994-09-20 2004-03-09 Eli Lilly And Company Benzofuran compounds, compositions, and methods
US6399634B1 (en) * 1994-09-20 2002-06-04 Eli Lilly And Company Benzothiophene compounds, compositions, and methods
US7501441B1 (en) * 1994-09-20 2009-03-10 Eli Lilly And Company Naphthyl compounds, intermediates, processes, compositions, and methods
US6417199B1 (en) * 1995-03-10 2002-07-09 Eli Lilly And Company 3-benzyl-benzothiophenes
US6395755B1 (en) 1995-03-10 2002-05-28 Eli Lilly And Company Benzothiophene pharmaceutical compounds
US5523309A (en) * 1995-03-10 1996-06-04 Eli Lilly And Company Benzofuran pharmaceutical compounds
US5622974A (en) * 1995-03-10 1997-04-22 Eli Lilly And Company α-substituted-3-benzyl-benzofurans
US6391892B1 (en) * 1995-03-10 2002-05-21 Eli Lilly And Company Naphthyl pharmaceutical compounds
US5705507A (en) * 1995-03-10 1998-01-06 Eli Lilly And Company Aplha-substituted-3-benzyl-benzofurans
US6444688B1 (en) * 1995-06-07 2002-09-03 Eli Lilly And Company Compounds and compositions with nitrogen-containing non-basic side chains
FR2764800B1 (fr) 1997-06-23 1999-09-10 Sanofi Sa Composition pharmaceutique solide contenant des derives de benzofuranne
FR2813306B1 (fr) * 2000-08-23 2005-10-21 Sanofi Synthelabo Aminoalkybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
FR2813308B1 (fr) * 2000-08-23 2005-07-01 Sanofi Synthelabo Aminoalkoxybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation ainsi que les compositions les contenant
FR2967067A1 (fr) 2010-11-10 2012-05-11 Sanofi Aventis Composition pharmaceutique et forme galenique a base de dronedarone et son procede de preparation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3248401A (en) * 1966-04-26 Diethylaminoe hoxybenzoyl benzofurans
US3929836A (en) * 1965-05-11 1975-12-30 Hoffmann La Roche 2-(2-Lower alkylamino-1-hydroxy-ethyl)-substituted benzofurans
US3627763A (en) * 1969-09-02 1971-12-14 Knut A Jaeggi Substituted 2-benzyl-benzofuran derivatives
GB1333471A (en) * 1971-01-27 1973-10-10 Labaz Imidazoline derivatives and process for preparing the same
GB1335403A (en) * 1971-04-29 1973-10-31 Labaz Pharmaceutical compositions containing benzofuran derivatives
GB1380145A (en) * 1972-05-02 1975-01-08 Labaz Acetamidine derivatives process for preparing the same and pharma ceutical uses thereof
GB1382602A (en) * 1972-06-01 1975-02-05 Labaz Benzodioxan compounds and process for preparing the same
GB1382742A (en) * 1972-09-19 1975-02-05 Labaz Benzofuran derivatives and process for preparing the same
FR2257273B1 (de) * 1974-01-15 1978-01-13 Labaz
GB1456323A (en) * 1974-06-06 1976-11-24 Labaz Benzothiophenes process for preparing them and pharmaceutical compositions containing the same
GB1472959A (en) * 1974-09-26 1977-05-11 Roche Products Ltd Benzofuran derivatives and a process for the manufacture thereof
IT1154888B (it) * 1980-11-12 1987-01-21 Menarini Sas Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione
JPS5973579A (ja) * 1982-10-19 1984-04-25 Kotobuki Seiyaku Kk ベンゾフラン又はベンゾチオフェン誘導体，この化合物を有効成分とする尿酸排泄剤及びその製造方法
US4806663A (en) * 1987-04-06 1989-02-21 The University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives

Also Published As

Publication number Publication date
AU2722288A (en) 1989-04-18
US4851554A (en) 1989-07-25
EP0380588A1 (de) 1990-08-08
WO1989002892A1 (en) 1989-04-06
DE3852107D1 (de) 1994-12-15
CA1327794C (en) 1994-03-15
AU618303B2 (en) 1991-12-19
DE3852107T2 (de) 1995-03-30
EP0380588A4 (en) 1991-04-03
JP2509683B2 (ja) 1996-06-26
JPH03501606A (ja) 1991-04-11
EP0380588B1 (de) 1994-11-09

Similar Documents

Publication Publication Date Title
DE3852107D1 (de) Bestimmte 3-substituierte 2-alkyl-benzofuran-derivate.
ATE32077T1 (de) 7-amino-azolo(1,5-a>-pyrimidine und diese enthaltende fungizide.
GB2078720B (en) 2-(3-oxobutyl)-2-formyl-1-tetralone intermediates
MY117092A (en) Chemotherapeutic pyrrolocarbazole derivatives
IL83141A0 (en) Solutions of oxazophorins having improved stability and their preparation
IL75273A (en) Cephalosporin derivatives,process for their preparation and pharmaceutical compositions containing them
JPS5756470A (en) Dibenzodiazepine derivative
NO164351C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.
EP0411912A3 (en) Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee