IL90650A - 6-(hetero) araliphatically substituted 4,5,7,8-tetrahydro- 6h-thiazolo(5,4-d) azepin-2-amines, their preparation and pharmaceutical compositions containing them - Google Patents

6-(hetero) araliphatically substituted 4,5,7,8-tetrahydro- 6h-thiazolo(5,4-d) azepin-2-amines, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL90650A
IL90650A IL90650A IL9065089A IL90650A IL 90650 A IL90650 A IL 90650A IL 90650 A IL90650 A IL 90650A IL 9065089 A IL9065089 A IL 9065089A IL 90650 A IL90650 A IL 90650A
Authority
IL
Israel
Prior art keywords
thiazolo
tetrahydro
azepin
hetero
amines
Prior art date
Application number
IL90650A
Other languages
English (en)
Other versions
IL90650A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL90650A0 publication Critical patent/IL90650A0/xx
Publication of IL90650A publication Critical patent/IL90650A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL90650A 1988-06-20 1989-06-19 6-(hetero) araliphatically substituted 4,5,7,8-tetrahydro- 6h-thiazolo(5,4-d) azepin-2-amines, their preparation and pharmaceutical compositions containing them IL90650A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3820775A DE3820775A1 (de) 1988-06-20 1988-06-20 Neue 4,5,7,8-tetrahydro-6h-thiazolo(5,4,-d)azepine, ihre herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
IL90650A0 IL90650A0 (en) 1990-01-18
IL90650A true IL90650A (en) 1993-05-13

Family

ID=6356840

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90650A IL90650A (en) 1988-06-20 1989-06-19 6-(hetero) araliphatically substituted 4,5,7,8-tetrahydro- 6h-thiazolo(5,4-d) azepin-2-amines, their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US5068325A (pt)
EP (1) EP0347766B1 (pt)
JP (1) JP2776892B2 (pt)
KR (1) KR0130202B1 (pt)
AT (1) ATE106082T1 (pt)
AU (1) AU617188B2 (pt)
CA (1) CA1337195C (pt)
DD (1) DD284021A5 (pt)
DE (2) DE3820775A1 (pt)
DK (1) DK301689A (pt)
ES (1) ES2057022T3 (pt)
FI (1) FI89492C (pt)
HU (1) HU201770B (pt)
IE (1) IE64661B1 (pt)
IL (1) IL90650A (pt)
NO (1) NO176357C (pt)
NZ (1) NZ229637A (pt)
PH (1) PH30664A (pt)
PT (1) PT90907B (pt)
SU (1) SU1731061A3 (pt)
ZA (1) ZA894636B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89351A0 (en) * 1988-03-14 1989-09-10 Lundbeck & Co As H 4,5,6,7-tetrahydroisothiazolo(4,5-c)pyridines,process for their preparation and pharmaceutical compositions containing them
US5424431A (en) * 1990-10-24 1995-06-13 Yamanouchi Pharmaceutical Co., Ltd. Thiazole derivatives
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
US5382596A (en) * 1993-08-05 1995-01-17 Whitby Research, Inc. Substituted 2-aminotetralins
DE4407141A1 (de) * 1994-03-04 1995-09-07 Thomae Gmbh Dr K Verwendung von in 6-Stellung substituierten 2-Amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d] azepinen als Arzneimittel mit antidepressiver Wirkung und deren Herstellung
US6232326B1 (en) 1998-07-14 2001-05-15 Jodi A. Nelson Treatment for schizophrenia and other dopamine system dysfunctions
US6417366B2 (en) * 1999-06-24 2002-07-09 Abbott Laboratories Preparation of quinoline-substituted carbonate and carbamate derivatives
US6369222B1 (en) 2000-07-18 2002-04-09 Hoffmann-La Roche Inc. mGluR antagonists and a method for their synthesis
DE10127926A1 (de) * 2001-06-08 2002-12-12 Bayer Ag 1,3-disubstituierte Indenkomplexe
JP5527668B2 (ja) * 2008-06-05 2014-06-18 エスケー バイオファーマスティカルズ カンパニー リミテッド ３−置換プロパンアミン化合物
CN104031072A (zh) * 2014-06-24 2014-09-10 重庆植恩药业有限公司 一种盐酸他利克索的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG17968A3 (bg) * 1970-08-14 1974-03-05 Dr. Karl Thomae Gmbh Метод за получаване на производни на азепина
BE795257A (fr) * 1972-02-10 1973-08-09 Thomae Gmbh Dr K Nouveaux oxazols
GB2173187B (en) * 1985-03-23 1988-05-18 Erba Farmitalia Condensed 2-substituted thiazole derivatives
JP3054738B2 (ja) * 1988-07-22 2000-06-19 武田薬品工業株式会社 チアゾロ［５，４―ｂ］アゼピン誘導体

Also Published As

Publication number Publication date
FI892991A0 (fi) 1989-06-19
DE58907706D1 (de) 1994-06-30
NO176357B (no) 1994-12-12
ATE106082T1 (de) 1994-06-15
PT90907A (pt) 1989-12-29
CA1337195C (en) 1995-10-03
FI89492C (fi) 1993-10-11
IE64661B1 (en) 1995-08-23
NO892435D0 (no) 1989-06-13
US5068325A (en) 1991-11-26
EP0347766A2 (de) 1989-12-27
EP0347766A3 (de) 1991-07-10
ES2057022T3 (es) 1994-10-16
JP2776892B2 (ja) 1998-07-16
IE891981L (en) 1989-12-20
AU617188B2 (en) 1991-11-21
DD284021A5 (de) 1990-10-31
NZ229637A (en) 1991-01-29
HU201770B (en) 1990-12-28
ZA894636B (en) 1991-02-27
JPH0245489A (ja) 1990-02-15
KR910000742A (ko) 1991-01-30
DE3820775A1 (de) 1989-12-21
NO176357C (no) 1995-03-22
FI892991A (fi) 1989-12-21
NO892435L (no) 1989-12-21
FI89492B (fi) 1993-06-30
SU1731061A3 (ru) 1992-04-30
EP0347766B1 (de) 1994-05-25
AU3659389A (en) 1989-12-21
DK301689D0 (da) 1989-06-19
PT90907B (pt) 1994-12-30
IL90650A0 (en) 1990-01-18
KR0130202B1 (ko) 1998-04-09
DK301689A (da) 1989-12-21
HUT51630A (en) 1990-05-28
PH30664A (en) 1997-09-16

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Legal Events

Date Code Title Description
RH Patent void