ES8704906A1 - Un procedimiento para la preparacion de derivados de benzodiazefinas. - Google Patents
Un procedimiento para la preparacion de derivados de benzodiazefinas.Info
- Publication number
- ES8704906A1 ES8704906A1 ES544523A ES544523A ES8704906A1 ES 8704906 A1 ES8704906 A1 ES 8704906A1 ES 544523 A ES544523 A ES 544523A ES 544523 A ES544523 A ES 544523A ES 8704906 A1 ES8704906 A1 ES 8704906A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- benzodiazepine derivatives
- benzodiazepine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/20—Nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/22—Sulfur atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
PROCEIDMIENTO PARA LA OBTENCION DE DERIVADOS DE BENZODIAZEPINAS, DE FORMULA (II) CON UN AGENTE NITROSANTE, EN PRESENCIA DE UNA BASE; SEGUIDA DE REDUCCION POR HIDROGENACION CATALITICA; RESOLUCION DEL COMPUESTO FORMADO POR COPULACION CON UN DERIVADO DE A-AMINOACIDO QUIRAL, DESPROTECCION POR TRATAMIENTO CON ACIDO CLORHIDRICO Y LAVADO CON UNA BASE, SEPARACION DE LOS DIASTEREOISOMEROS POR CRISTALIZACION Y DESACILACION DE ESTOS; Y, FINALMENTE, ACILACION CON UN ACIDO CARBOXILICO EN PRESENCIA DE UN REACTIVO COPULANTE, PARA FORMAR EL COMPUESTO DE FORMULA (I) EN LA QUE TODOS LOS SIMBOLOS PUEDEN SER VARIOS TIPOS DE RADICALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANALGESICOS Y PARA EL TRATAMIENTO DE TRASTORNOS DE LOS SISTEMAS NERVIOSO CENTRAL Y GASTROINTESTINAL.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62485484A | 1984-06-26 | 1984-06-26 | |
US70527285A | 1985-02-25 | 1985-02-25 | |
US74197285A | 1985-06-10 | 1985-06-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8704906A1 true ES8704906A1 (es) | 1987-04-16 |
ES544523A0 ES544523A0 (es) | 1987-04-16 |
Family
ID=27417360
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES544523A Expired ES8704906A1 (es) | 1984-06-26 | 1985-06-25 | Un procedimiento para la preparacion de derivados de benzodiazefinas. |
ES551504A Expired ES8706132A1 (es) | 1984-06-26 | 1986-01-31 | Un procedimiento para la preparacion de analogos de benzodiazepina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES551504A Expired ES8706132A1 (es) | 1984-06-26 | 1986-01-31 | Un procedimiento para la preparacion de analogos de benzodiazepina |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0167919B1 (es) |
JP (1) | JP2603214B2 (es) |
KR (1) | KR900003406B1 (es) |
AT (1) | ATE88998T1 (es) |
AU (2) | AU4415285A (es) |
CA (1) | CA1332410C (es) |
DE (1) | DE3587316T2 (es) |
DK (1) | DK175264B1 (es) |
ES (2) | ES8704906A1 (es) |
GR (1) | GR851539B (es) |
HK (1) | HK15397A (es) |
IE (1) | IE59900B1 (es) |
IL (1) | IL75587A0 (es) |
NO (1) | NO173651C (es) |
NZ (1) | NZ212502A (es) |
PT (1) | PT80717B (es) |
YU (1) | YU46738B (es) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
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US4820834A (en) * | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
DE3586445T2 (de) * | 1984-06-26 | 1993-01-14 | Merck & Co Inc | Kondensierte benzo-laktam-verbindungen und deren pharmazeutische zusammensetzungen. |
US4755508A (en) * | 1984-06-26 | 1988-07-05 | Merck & Co., Inc. | Benzodiazepine analogs and use as antogonists of gastrin and cholecystokinin |
DE3514696A1 (de) * | 1985-04-24 | 1986-11-06 | Bayer Ag, 5090 Leverkusen | N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung |
EP0253571B1 (en) * | 1986-07-14 | 1989-08-23 | Merck & Co. Inc. | Process for resolution and race mization of amines with acidic alpha-hydrogens |
JPH01211939A (ja) * | 1988-02-18 | 1989-08-25 | Nec Kyushu Ltd | イオン注入装置 |
FR2630440B1 (fr) * | 1988-04-25 | 1991-09-20 | Jouveinal Sa | Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique |
US4970207A (en) * | 1988-07-07 | 1990-11-13 | Fujisawa Pharmaceutical Company, Ltd. | Benzodiazepine derivatives |
IL91361A (en) * | 1988-09-09 | 1994-10-07 | Fujisawa Pharmaceutical Co | Benzodiazepinone compounds [4,1] connected via positions 1 and 9 and carrying two transducers, processes for their preparation and pharmaceutical preparations containing them |
US4957915A (en) * | 1989-02-27 | 1990-09-18 | Biomeasure, Inc. | Benzodiazepine analogs |
PH26955A (en) * | 1989-03-08 | 1992-12-03 | Kali Chemie Pharma Gmbh | Novel 1,7-fused 1H-indole-2-carboxylic acid N-(1,4-benzodiazepin-3-YL) amides |
ATE154135T1 (de) * | 1989-03-10 | 1997-06-15 | Hoffmann La Roche | Reagenzien zum nachweis von drogen |
EP0411668B2 (en) * | 1989-08-04 | 1998-11-11 | MERCK SHARP & DOHME LTD. | Central cholecystokinin antagonists for treatment of psychiatric disorders |
FR2652352A1 (fr) * | 1989-09-28 | 1991-03-29 | Jouveinal Sa | Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique. |
FR2659331A1 (fr) * | 1990-03-08 | 1991-09-13 | Adir | Nouveaux derives de la 4h-pyrrolo [1,2-a] thieno [3,2-f] [1,4]-diazepine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
CA2056809A1 (en) * | 1990-12-07 | 1992-06-08 | Mark G. Bock | Benzodiazepine analogs |
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EP0523845A3 (en) * | 1991-06-14 | 1993-11-18 | Merck & Co Inc | New benzodiazepine analogs |
WO1993007131A1 (en) * | 1991-10-10 | 1993-04-15 | Merck Sharp & Dohme Limited | Benzodiazepine derivatives and their use as antagonists of cholecystokinin and/or gastrin receptors |
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GB9203790D0 (en) * | 1992-02-21 | 1992-04-08 | Merck Sharp & Dohme | Therapeutic agents |
US5597915A (en) * | 1992-03-16 | 1997-01-28 | Merck Sharp & Dohme Ltd. | Benzodiazepine derivatives, compositions containing them and their use in therapy |
US5681833A (en) * | 1992-03-24 | 1997-10-28 | Merck, Sharp & Dohme Ltd. | Benzodiazepine derivatives |
US5360802A (en) * | 1992-05-11 | 1994-11-01 | Merck Sharpe & Dohme Ltd. | Benzodiazepine derivatives, compositions containing them and their use in therapy |
WO1994000438A1 (en) * | 1992-06-24 | 1994-01-06 | Yamanouchi Pharmaceutical Co., Ltd. | Novel benzodiazepine derivative |
FR2694006A1 (fr) * | 1992-07-22 | 1994-01-28 | Esteve Labor Dr | Amides dérivés de benzohétérocyles. |
AU671141B2 (en) * | 1992-07-29 | 1996-08-15 | Merck Sharp & Dohme Limited | Benzodiazepine derivatives |
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CH408045A (de) * | 1959-12-10 | 1966-02-28 | Hoffmann La Roche | Verfahren zur Herstellung von Benzophenonderivaten |
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-
1985
- 1985-06-19 CA CA000484488A patent/CA1332410C/en not_active Expired - Fee Related
- 1985-06-20 IL IL75587A patent/IL75587A0/xx not_active IP Right Cessation
- 1985-06-20 NZ NZ212502A patent/NZ212502A/xx unknown
- 1985-06-24 GR GR851539A patent/GR851539B/el unknown
- 1985-06-25 AT AT85107842T patent/ATE88998T1/de not_active IP Right Cessation
- 1985-06-25 NO NO852558A patent/NO173651C/no unknown
- 1985-06-25 DE DE85107842T patent/DE3587316T2/de not_active Expired - Lifetime
- 1985-06-25 ES ES544523A patent/ES8704906A1/es not_active Expired
- 1985-06-25 DK DK198502872A patent/DK175264B1/da not_active IP Right Cessation
- 1985-06-25 IE IE158285A patent/IE59900B1/en not_active IP Right Cessation
- 1985-06-25 AU AU44152/85A patent/AU4415285A/en not_active Abandoned
- 1985-06-25 EP EP85107842A patent/EP0167919B1/en not_active Expired - Lifetime
- 1985-06-26 YU YU106785A patent/YU46738B/sh unknown
- 1985-06-26 PT PT80717A patent/PT80717B/pt unknown
- 1985-06-26 JP JP60138064A patent/JP2603214B2/ja not_active Expired - Lifetime
- 1985-06-26 KR KR1019850004551A patent/KR900003406B1/ko not_active IP Right Cessation
-
1986
- 1986-01-31 ES ES551504A patent/ES8706132A1/es not_active Expired
-
1989
- 1989-11-10 AU AU44563/89A patent/AU640113B2/en not_active Ceased
-
1997
- 1997-02-05 HK HK15397A patent/HK15397A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR860000270A (ko) | 1986-01-27 |
DK287285D0 (da) | 1985-06-25 |
PT80717A (en) | 1985-07-01 |
ES8706132A1 (es) | 1987-06-01 |
PT80717B (pt) | 1987-10-20 |
YU46738B (sh) | 1994-04-05 |
KR900003406B1 (ko) | 1990-05-18 |
DK287285A (da) | 1986-02-25 |
NO173651B (no) | 1993-10-04 |
IE851582L (en) | 1985-12-26 |
NZ212502A (en) | 1989-03-29 |
JPS6163666A (ja) | 1986-04-01 |
GR851539B (es) | 1985-11-25 |
AU640113B2 (en) | 1993-08-19 |
NO173651C (no) | 1994-01-12 |
ES551504A0 (es) | 1987-06-01 |
ATE88998T1 (de) | 1993-05-15 |
CA1332410C (en) | 1994-10-11 |
IL75587A0 (en) | 1985-10-31 |
ES544523A0 (es) | 1987-04-16 |
YU106785A (en) | 1988-12-31 |
EP0167919A2 (en) | 1986-01-15 |
AU4415285A (en) | 1986-01-02 |
EP0167919A3 (en) | 1986-11-05 |
DE3587316D1 (de) | 1993-06-09 |
EP0167919B1 (en) | 1993-05-05 |
NO852558L (no) | 1985-12-27 |
JP2603214B2 (ja) | 1997-04-23 |
IE59900B1 (en) | 1994-04-20 |
AU4456389A (en) | 1990-04-05 |
DE3587316T2 (de) | 1993-11-04 |
HK15397A (en) | 1997-02-14 |
DK175264B1 (da) | 2004-08-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20070123 |