ZA894636B - Novel 4,5,7,8-tetrahydro-6h-thiazolo(5,4-d)azepines,their preparation and their use as pharmaceuticals - Google Patents

Novel 4,5,7,8-tetrahydro-6h-thiazolo(5,4-d)azepines,their preparation and their use as pharmaceuticals

Info

Publication number
ZA894636B
ZA894636B ZA894636A ZA894636A ZA894636B ZA 894636 B ZA894636 B ZA 894636B ZA 894636 A ZA894636 A ZA 894636A ZA 894636 A ZA894636 A ZA 894636A ZA 894636 B ZA894636 B ZA 894636B
Authority
ZA
South Africa
Prior art keywords
azepines
thiazolo
tetrahydro
pharmaceuticals
novel
Prior art date
Application number
ZA894636A
Other languages
English (en)
Inventor
Wolfgang Dr Grell
Grell Dr Wolfgang
Rudolf Dr Hurnaus
Hurnaus Dr Rudolf
Manfred Dr Reiffen
Reiffen Dr Manfred
Robert Dr Sauter
Sauter Dr Robert
Ludwig Dr Pichler
Pichler Dr Ludwig
Walter Dr Kobinger
Kobinger Dr Walter
Michael Dr Entzeroth
Entzeroth Dr Michael
Guenter Dr Schingnitz
Schingnitz Dr Guenter
Joachim Dr Mierau
Mierau Dr Joachim
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA894636B publication Critical patent/ZA894636B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA894636A 1988-06-20 1989-06-19 Novel 4,5,7,8-tetrahydro-6h-thiazolo(5,4-d)azepines,their preparation and their use as pharmaceuticals ZA894636B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3820775A DE3820775A1 (de) 1988-06-20 1988-06-20 Neue 4,5,7,8-tetrahydro-6h-thiazolo(5,4,-d)azepine, ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA894636B true ZA894636B (en) 1991-02-27

Family

ID=6356840

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894636A ZA894636B (en) 1988-06-20 1989-06-19 Novel 4,5,7,8-tetrahydro-6h-thiazolo(5,4-d)azepines,their preparation and their use as pharmaceuticals

Country Status (21)

Country Link
US (1) US5068325A (xx)
EP (1) EP0347766B1 (xx)
JP (1) JP2776892B2 (xx)
KR (1) KR0130202B1 (xx)
AT (1) ATE106082T1 (xx)
AU (1) AU617188B2 (xx)
CA (1) CA1337195C (xx)
DD (1) DD284021A5 (xx)
DE (2) DE3820775A1 (xx)
DK (1) DK301689A (xx)
ES (1) ES2057022T3 (xx)
FI (1) FI89492C (xx)
HU (1) HU201770B (xx)
IE (1) IE64661B1 (xx)
IL (1) IL90650A (xx)
NO (1) NO176357C (xx)
NZ (1) NZ229637A (xx)
PH (1) PH30664A (xx)
PT (1) PT90907B (xx)
SU (1) SU1731061A3 (xx)
ZA (1) ZA894636B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89351A0 (en) * 1988-03-14 1989-09-10 Lundbeck & Co As H 4,5,6,7-tetrahydroisothiazolo(4,5-c)pyridines,process for their preparation and pharmaceutical compositions containing them
US5424431A (en) * 1990-10-24 1995-06-13 Yamanouchi Pharmaceutical Co., Ltd. Thiazole derivatives
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
US5382596A (en) * 1993-08-05 1995-01-17 Whitby Research, Inc. Substituted 2-aminotetralins
DE4407141A1 (de) * 1994-03-04 1995-09-07 Thomae Gmbh Dr K Verwendung von in 6-Stellung substituierten 2-Amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d] azepinen als Arzneimittel mit antidepressiver Wirkung und deren Herstellung
US6232326B1 (en) 1998-07-14 2001-05-15 Jodi A. Nelson Treatment for schizophrenia and other dopamine system dysfunctions
US6417366B2 (en) * 1999-06-24 2002-07-09 Abbott Laboratories Preparation of quinoline-substituted carbonate and carbamate derivatives
US6369222B1 (en) 2000-07-18 2002-04-09 Hoffmann-La Roche Inc. mGluR antagonists and a method for their synthesis
DE10127926A1 (de) 2001-06-08 2002-12-12 Bayer Ag 1,3-disubstituierte Indenkomplexe
CN102026988B (zh) * 2008-06-05 2013-07-03 爱思开生物制药株式会社 3-取代的丙胺化合物
CN104031072A (zh) * 2014-06-24 2014-09-10 重庆植恩药业有限公司 一种盐酸他利克索的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG17786A3 (xx) * 1970-08-14 1973-12-25
BE795257A (fr) * 1972-02-10 1973-08-09 Thomae Gmbh Dr K Nouveaux oxazols
GB2173187B (en) * 1985-03-23 1988-05-18 Erba Farmitalia Condensed 2-substituted thiazole derivatives
JP3054738B2 (ja) * 1988-07-22 2000-06-19 武田薬品工業株式会社 チアゾロ［５，４―ｂ］アゼピン誘導体

Also Published As

Publication number Publication date
NO892435L (no) 1989-12-21
AU3659389A (en) 1989-12-21
KR0130202B1 (ko) 1998-04-09
PH30664A (en) 1997-09-16
IE64661B1 (en) 1995-08-23
EP0347766B1 (de) 1994-05-25
AU617188B2 (en) 1991-11-21
DK301689D0 (da) 1989-06-19
PT90907B (pt) 1994-12-30
CA1337195C (en) 1995-10-03
NO176357B (no) 1994-12-12
NO892435D0 (no) 1989-06-13
NO176357C (no) 1995-03-22
FI892991A0 (fi) 1989-06-19
US5068325A (en) 1991-11-26
HU201770B (en) 1990-12-28
DE58907706D1 (de) 1994-06-30
IE891981L (en) 1989-12-20
JPH0245489A (ja) 1990-02-15
EP0347766A3 (de) 1991-07-10
DK301689A (da) 1989-12-21
KR910000742A (ko) 1991-01-30
ES2057022T3 (es) 1994-10-16
NZ229637A (en) 1991-01-29
FI89492B (fi) 1993-06-30
EP0347766A2 (de) 1989-12-27
DD284021A5 (de) 1990-10-31
PT90907A (pt) 1989-12-29
DE3820775A1 (de) 1989-12-21
FI892991A (fi) 1989-12-21
ATE106082T1 (de) 1994-06-15
JP2776892B2 (ja) 1998-07-16
HUT51630A (en) 1990-05-28
IL90650A (en) 1993-05-13
IL90650A0 (en) 1990-01-18
SU1731061A3 (ru) 1992-04-30
FI89492C (fi) 1993-10-11

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