IL85545A - 8-(4(-(2-pyrimidinyl)-1-piperazinyl)-but-2-inyl(or 2-enyl))-8-aza-spiro(4.5)decane-7-9-diones,process for their preparation and their use as intermediates in the preparation of anxioselective compounds - Google Patents

8-(4(-(2-pyrimidinyl)-1-piperazinyl)-but-2-inyl(or 2-enyl))-8-aza-spiro(4.5)decane-7-9-diones,process for their preparation and their use as intermediates in the preparation of anxioselective compounds

Info

Publication number
IL85545A
IL85545A IL85545A IL8554588A IL85545A IL 85545 A IL85545 A IL 85545A IL 85545 A IL85545 A IL 85545A IL 8554588 A IL8554588 A IL 8554588A IL 85545 A IL85545 A IL 85545A
Authority
IL
Israel
Prior art keywords
preparation
anxioselective
inyl
diones
enyl
Prior art date
Application number
IL85545A
Other languages
English (en)
Other versions
IL85545A0 (en
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU71787A external-priority patent/HU198204B/hu
Priority claimed from HU71687A external-priority patent/HU197313B/hu
Priority claimed from HU71887A external-priority patent/HU198477B/hu
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IL85545A0 publication Critical patent/IL85545A0/xx
Publication of IL85545A publication Critical patent/IL85545A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL85545A 1987-02-25 1988-02-25 8-(4(-(2-pyrimidinyl)-1-piperazinyl)-but-2-inyl(or 2-enyl))-8-aza-spiro(4.5)decane-7-9-diones,process for their preparation and their use as intermediates in the preparation of anxioselective compounds IL85545A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU71787A HU198204B (en) 1987-02-25 1987-02-25 Process for production of derivatives of piperasine
HU71687A HU197313B (en) 1987-02-25 1987-02-25 Process for producing 8-azaspiro <4.5> decane-7,9-dione-8-propine-/2/
HU71887A HU198477B (en) 1987-02-25 1987-02-25 Process for producing pyrimidinyl piperazine derivatives

Publications (2)

Publication Number Publication Date
IL85545A0 IL85545A0 (en) 1988-08-31
IL85545A true IL85545A (en) 1992-05-25

Family

ID=27269942

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85545A IL85545A (en) 1987-02-25 1988-02-25 8-(4(-(2-pyrimidinyl)-1-piperazinyl)-but-2-inyl(or 2-enyl))-8-aza-spiro(4.5)decane-7-9-diones,process for their preparation and their use as intermediates in the preparation of anxioselective compounds

Country Status (20)

Country Link
KR (1) KR880009955A (fr)
CN (1) CN88100923A (fr)
AT (1) AT395851B (fr)
BE (1) BE1001464A3 (fr)
CA (1) CA1300141C (fr)
CH (1) CH677924A5 (fr)
CS (1) CS274423B2 (fr)
DE (1) DE3806009C2 (fr)
DK (1) DK99388A (fr)
ES (1) ES2009236A6 (fr)
FI (1) FI880895A (fr)
FR (1) FR2615853B1 (fr)
GB (1) GB2201417B (fr)
GR (1) GR1002245B (fr)
IL (1) IL85545A (fr)
IT (1) IT1217342B (fr)
NL (1) NL8800484A (fr)
PL (1) PL152958B1 (fr)
SE (1) SE8800651L (fr)
YU (1) YU46441B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU217129B (hu) * 1993-07-16 1999-11-29 EGIS Gyógyszergyár Rt. Eljárás nagy tisztaságú buspiron gyógyászati hatóanyag előállítására
KR950014099A (ko) * 1993-11-10 1995-06-15 장기하 N-(2-피리미딜)피페라지닐 부틸아미드의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE300422B (fr) * 1964-07-03 1968-04-29 Astra Ab
DE1545543B1 (de) * 1964-07-03 1970-01-22 Astra Apotekarnes Kem Fab 4-Aminobutinylimide,ihre Salze und Verfahren zu deren Herstellung
US3354178A (en) * 1965-04-09 1967-11-21 Sterling Drug Inc Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
JPS6310760A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd イミド誘導体の新規製造法
JPS6310786A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd 新規イミド誘導体およびその製造法

Also Published As

Publication number Publication date
GR1002245B (en) 1996-04-22
IT8819545A0 (it) 1988-02-25
BE1001464A3 (fr) 1989-11-07
GB8804385D0 (en) 1988-03-23
GR880100108A (el) 1988-12-16
CS274423B2 (en) 1991-04-11
ES2009236A6 (es) 1989-09-16
CS122288A2 (en) 1990-08-14
DK99388A (da) 1988-08-26
FR2615853B1 (fr) 1991-01-04
IL85545A0 (en) 1988-08-31
KR880009955A (ko) 1988-10-06
CN88100923A (zh) 1988-09-28
IT1217342B (it) 1990-03-22
CA1300141C (fr) 1992-05-05
NL8800484A (nl) 1988-09-16
FI880895A (fi) 1988-08-26
PL152958B1 (en) 1991-02-28
SE8800651L (sv) 1988-08-26
SE8800651D0 (sv) 1988-02-25
GB2201417A (en) 1988-09-01
DE3806009A1 (de) 1988-09-08
GB2201417B (en) 1990-10-31
YU46441B (sh) 1993-10-20
PL270815A1 (en) 1989-04-03
ATA47688A (de) 1992-08-15
CH677924A5 (fr) 1991-07-15
FR2615853A1 (fr) 1988-12-02
FI880895A0 (fi) 1988-02-25
YU36288A (en) 1989-10-31
DK99388D0 (da) 1988-02-25
DE3806009C2 (de) 1996-09-12
AT395851B (de) 1993-03-25

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