IL84505A - 4-alkyl-4,7-dihydro-7-oxothieno(3,2-b)-pyridine-6-carboxamides,their preparation and pharmaceutical compositions containing them - Google Patents
4-alkyl-4,7-dihydro-7-oxothieno(3,2-b)-pyridine-6-carboxamides,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL84505A IL84505A IL84505A IL8450587A IL84505A IL 84505 A IL84505 A IL 84505A IL 84505 A IL84505 A IL 84505A IL 8450587 A IL8450587 A IL 8450587A IL 84505 A IL84505 A IL 84505A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- alkyl
- oxothieno
- carboxamides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Liquid Crystal Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868627698A GB8627698D0 (en) | 1986-11-20 | 1986-11-20 | Therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
IL84505A true IL84505A (en) | 1990-12-23 |
Family
ID=10607612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL84505A IL84505A (en) | 1986-11-20 | 1987-11-17 | 4-alkyl-4,7-dihydro-7-oxothieno(3,2-b)-pyridine-6-carboxamides,their preparation and pharmaceutical compositions containing them |
Country Status (24)
Country | Link |
---|---|
US (1) | US4877793A (es) |
EP (1) | EP0269295B1 (es) |
JP (1) | JPS63141984A (es) |
KR (1) | KR880006247A (es) |
CN (1) | CN1019491B (es) |
AT (1) | ATE64736T1 (es) |
AU (1) | AU599721B2 (es) |
DD (1) | DD282690A5 (es) |
DE (1) | DE3771039D1 (es) |
DK (1) | DK599887A (es) |
ES (1) | ES2038188T3 (es) |
FI (1) | FI875020A (es) |
GB (1) | GB8627698D0 (es) |
GR (1) | GR3002500T3 (es) |
HU (1) | HU198060B (es) |
IL (1) | IL84505A (es) |
JO (1) | JO1520B1 (es) |
MX (1) | MX9428A (es) |
NO (1) | NO874834L (es) |
NZ (1) | NZ222554A (es) |
PH (1) | PH23293A (es) |
PL (1) | PL149617B1 (es) |
PT (1) | PT86115B (es) |
ZA (1) | ZA878306B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8726950D0 (en) * | 1987-11-18 | 1987-12-23 | Boots Co Plc | Chemical process |
NZ230711A (en) * | 1988-09-23 | 1990-10-26 | Ortho Pharma Corp | Substituted thienopyrans as antihypertensive agents |
ZA903588B (en) * | 1989-05-16 | 1991-02-27 | Merrell Dow Pharma | Excitatory amino acid antagonists |
US5026700A (en) * | 1989-05-16 | 1991-06-25 | Merrell Dow Pharmaceuticals | Certain quinolines and thienopyridines as excitatory amino acid antagonists |
US5219864A (en) * | 1991-03-12 | 1993-06-15 | Kyowa Hakko Kogyo Co., Ltd. | Thienopyridine derivatives |
JP2699794B2 (ja) * | 1992-03-12 | 1998-01-19 | 三菱化学株式会社 | チエノ〔3,2−b〕ピリジン誘導体 |
DE4227747A1 (de) * | 1992-08-21 | 1994-02-24 | Basf Ag | Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung |
CA2339484A1 (en) * | 1998-08-03 | 2000-02-17 | Robert A. O'brien | Pyridinones for the treatment of sexual dysfunction |
US6562838B2 (en) * | 2001-01-26 | 2003-05-13 | R. T. Alamo Ventures I, L.L.C. | Treatment of cardiovascular disease with quinolinone enantiomers |
US6458804B1 (en) | 2001-01-26 | 2002-10-01 | R.T. Alamo Venturesi, Llc | Methods for the treatment of central nervous system disorders in certain patient groups |
US6451813B1 (en) | 2001-01-26 | 2002-09-17 | R. T. Alamo Ventures I, Llc | Treatment of gastroparesis in certain patient groups |
US8329924B2 (en) | 2001-06-11 | 2012-12-11 | Vertex Pharmaceuticals (Canada) Incorporated | Compounds and methods for the treatment or prevention of Flavivirus infections |
JP4544857B2 (ja) * | 2001-06-11 | 2010-09-15 | ヴァイロケム ファーマ インコーポレイテッド | Flavivirus感染の治療または予防のための化合物および方法 |
WO2003020728A1 (en) | 2001-08-30 | 2003-03-13 | Pharmacia & Upjohn Company | 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS |
AR038117A1 (es) | 2002-01-14 | 2004-12-29 | Upjohn Co | Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida |
AR038294A1 (es) | 2002-01-14 | 2005-01-12 | Upjohn Co | Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales |
AR038118A1 (es) | 2002-01-14 | 2004-12-29 | Upjohn Co | Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales |
US7402608B2 (en) | 2002-12-10 | 2008-07-22 | Virochem Pharma Inc. | Compounds and methods for the treatment or prevention of Flavivirus infections |
KR20080016597A (ko) | 2005-05-13 | 2008-02-21 | 바이로켐 파마 인코포레이티드 | 플라비바이러스 감염의 예방 또는 치료용 화합물 및 그의예방 또는 치료 방법 |
JP2008093872A (ja) * | 2006-10-09 | 2008-04-24 | Kouritsu Kogyo:Kk | 表示装置 |
SI2104674T1 (sl) | 2006-11-15 | 2013-09-30 | Vertex Pharmaceuticals (Canada) Incorporated | Tiofenski analogi za zdravljenje ali preprečevanje flavivirusnih infekcij |
PL2280952T3 (pl) * | 2008-05-05 | 2012-10-31 | Merck Patent Gmbh | Pochodne tienopirydonowe jako aktywatory kinazy białkowej aktywowanej przez amp |
CN103517936A (zh) * | 2011-04-27 | 2014-01-15 | 巴斯夫欧洲公司 | 基于二噻吩并吡啶酮共聚物的半导体材料 |
HRP20211583T1 (hr) * | 2017-05-11 | 2022-01-07 | Bristol-Myers Squibb Company | Tienopiridini i benzotiofeni korisni kao irak4 inhibitori |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3903095A (en) * | 1972-02-18 | 1975-09-02 | Merck & Co Inc | Certain substituted-thieno{8 3,2-c{9 -pyridines |
US3997545A (en) * | 1973-07-23 | 1976-12-14 | Takeda Chemical Industries, Ltd. | Thienopyridine-carboxylic acid derivatives |
NZ193167A (en) * | 1979-03-27 | 1984-08-24 | Boots Co Plc | Quinoline derivatives and pharmaceutical compositions |
JPS5742690A (en) * | 1980-08-28 | 1982-03-10 | Kanebo Ltd | Thieno 3,2-b pyridinecarboxylic acid derivative |
IE51542B1 (en) * | 1980-09-26 | 1987-01-07 | Boots Co Ltd | Therapeutic agents |
EP0126970A3 (en) * | 1983-04-27 | 1985-11-06 | Beecham Group Plc | Anxiolytic and anti-depressant thienopyridine derivatives |
PT79031B (en) * | 1983-08-20 | 1986-08-22 | Boots Co Plc | Therapeutic agents |
EP0149519B1 (en) * | 1984-01-13 | 1990-06-27 | The Boots Company PLC | Use of quinolones for the manufacture of a composition for the treatment of heart failure. |
AU578712B2 (en) * | 1984-07-13 | 1988-11-03 | Pandrol Limited | Improvements in or relating to rail pads and rail assemblies including such pads |
EP0172004B1 (en) * | 1984-08-15 | 1990-03-21 | The Boots Company PLC | Quinolinones, process for their preparation and pharmaceutical compositions containing them |
GB8515209D0 (en) * | 1985-06-15 | 1985-07-17 | Boots Co Plc | Therapeutic agents |
GB8515207D0 (en) * | 1985-06-15 | 1985-07-17 | Boots Co Plc | Therapeutic agents |
-
1986
- 1986-11-20 GB GB868627698A patent/GB8627698D0/en active Pending
-
1987
- 1987-11-05 EP EP87309788A patent/EP0269295B1/en not_active Expired - Lifetime
- 1987-11-05 DE DE8787309788T patent/DE3771039D1/de not_active Expired - Fee Related
- 1987-11-05 ZA ZA878306A patent/ZA878306B/xx unknown
- 1987-11-05 ES ES198787309788T patent/ES2038188T3/es not_active Expired - Lifetime
- 1987-11-05 AT AT87309788T patent/ATE64736T1/de not_active IP Right Cessation
- 1987-11-06 PH PH36041A patent/PH23293A/en unknown
- 1987-11-11 PT PT86115A patent/PT86115B/pt not_active IP Right Cessation
- 1987-11-13 FI FI875020A patent/FI875020A/fi not_active Application Discontinuation
- 1987-11-16 DK DK599887A patent/DK599887A/da not_active Application Discontinuation
- 1987-11-16 NZ NZ222554A patent/NZ222554A/xx unknown
- 1987-11-17 IL IL84505A patent/IL84505A/xx unknown
- 1987-11-17 JO JO19871520A patent/JO1520B1/en active
- 1987-11-18 DD DD87309168A patent/DD282690A5/de not_active IP Right Cessation
- 1987-11-19 NO NO874834A patent/NO874834L/no unknown
- 1987-11-19 JP JP62293042A patent/JPS63141984A/ja active Pending
- 1987-11-19 US US07/122,394 patent/US4877793A/en not_active Expired - Fee Related
- 1987-11-19 MX MX942887A patent/MX9428A/es unknown
- 1987-11-19 HU HU875137A patent/HU198060B/hu not_active IP Right Cessation
- 1987-11-20 KR KR870013058A patent/KR880006247A/ko not_active Application Discontinuation
- 1987-11-20 CN CN87107975A patent/CN1019491B/zh not_active Expired
- 1987-11-20 AU AU81440/87A patent/AU599721B2/en not_active Ceased
- 1987-11-20 PL PL1987268925A patent/PL149617B1/pl unknown
-
1991
- 1991-08-19 GR GR91401211T patent/GR3002500T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US4877793A (en) | 1989-10-31 |
DK599887D0 (da) | 1987-11-16 |
PT86115A (en) | 1987-12-01 |
PL149617B1 (en) | 1990-03-31 |
PH23293A (en) | 1989-06-30 |
FI875020A0 (fi) | 1987-11-13 |
AU599721B2 (en) | 1990-07-26 |
JO1520B1 (en) | 1989-01-25 |
NO874834L (no) | 1988-05-24 |
PT86115B (pt) | 1990-08-31 |
DE3771039D1 (de) | 1991-08-01 |
EP0269295A1 (en) | 1988-06-01 |
NO874834D0 (no) | 1987-11-19 |
JPS63141984A (ja) | 1988-06-14 |
EP0269295B1 (en) | 1991-06-26 |
MX9428A (es) | 1993-10-01 |
GB8627698D0 (en) | 1986-12-17 |
GR3002500T3 (en) | 1992-12-30 |
ATE64736T1 (de) | 1991-07-15 |
ZA878306B (en) | 1988-05-02 |
KR880006247A (ko) | 1988-07-22 |
CN87107975A (zh) | 1988-06-01 |
DD282690A5 (de) | 1990-09-19 |
AU8144087A (en) | 1988-05-26 |
DK599887A (da) | 1988-05-21 |
FI875020A (fi) | 1988-05-21 |
ES2038188T3 (es) | 1993-07-16 |
HU198060B (en) | 1989-07-28 |
HUT47289A (en) | 1989-02-28 |
PL268925A1 (en) | 1988-09-01 |
NZ222554A (en) | 1989-08-29 |
CN1019491B (zh) | 1992-12-16 |
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