IL84203A - Insulin preparations and their production - Google Patents

Insulin preparations and their production

Info

Publication number
IL84203A
IL84203A IL84203A IL8420387A IL84203A IL 84203 A IL84203 A IL 84203A IL 84203 A IL84203 A IL 84203A IL 8420387 A IL8420387 A IL 8420387A IL 84203 A IL84203 A IL 84203A
Authority
IL
Israel
Prior art keywords
production
insulin preparations
insulin
preparations
Prior art date
Application number
IL84203A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK503386A external-priority patent/DK503386D0/da
Priority claimed from DK356987A external-priority patent/DK356987D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL84203A publication Critical patent/IL84203A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
IL84203A 1986-10-20 1987-10-19 Insulin preparations and their production IL84203A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK503386A DK503386D0 (da) 1986-10-20 1986-10-20 Peptidpraeparater
DK356987A DK356987D0 (enExample) 1987-07-10 1987-07-10

Publications (1)

Publication Number Publication Date
IL84203A true IL84203A (en) 1993-04-04

Family

ID=26067111

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84203A IL84203A (en) 1986-10-20 1987-10-19 Insulin preparations and their production

Country Status (18)

Country Link
US (1) US5070186A (enExample)
EP (1) EP0265213B1 (enExample)
KR (1) KR880004819A (enExample)
CN (1) CN87107049A (enExample)
AU (1) AU616381B2 (enExample)
CA (1) CA1316819C (enExample)
DE (1) DE3778287D1 (enExample)
ES (1) ES2033871T3 (enExample)
FI (1) FI86254C (enExample)
GR (1) GR3004912T3 (enExample)
HU (1) HU201475B (enExample)
IE (1) IE60264B1 (enExample)
IL (1) IL84203A (enExample)
NO (1) NO170754C (enExample)
NZ (1) NZ222214A (enExample)
PH (1) PH23446A (enExample)
PT (1) PT85949B (enExample)
YU (1) YU46665B (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5534488A (en) * 1993-08-13 1996-07-09 Eli Lilly And Company Insulin formulation
AR002976A1 (es) * 1995-03-31 1998-05-27 Lilly Co Eli Formulaciones farmaceuticas parenterales de efecto prolongado de insulina; cristales de dichos analogos aplicables en dichas formulaciones yprocedimiento de las formulaciones mencionadas
EP1044016B1 (en) * 1998-01-09 2005-03-16 Novo Nordisk A/S Stabilised insulin compositions
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
DE10114178A1 (de) * 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
WO2003017915A1 (en) * 2001-08-27 2003-03-06 Novo Nordisk A/S A cartridge and a medical delivery system accommodating such a cartridge
EP1585771A4 (en) * 2002-12-31 2006-11-29 Altus Pharmaceuticals Inc COMPLEXES OF PROTEIN CRYSTALS AND IONIC POLYMERS
BR0317888A (pt) * 2002-12-31 2005-12-06 Altus Pharmaceuticals Inc Cristais do hormÈnio do crescimento humano e processos para preparação dos mesmos
AU2006330833A1 (en) * 2005-12-23 2007-07-05 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them
WO2008015099A2 (en) 2006-07-31 2008-02-07 Novo Nordisk A/S Pegylated, extended insulins
BRPI0717098B8 (pt) 2006-09-22 2021-05-25 Novo Nordisk As análogos de insulina humana resistentes à protease, composição farmacêutica e processo para sua preparação
WO2008132224A2 (en) 2007-04-30 2008-11-06 Novo Nordisk A/S Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
US20100120660A1 (en) * 2007-04-30 2010-05-13 Per Balschmidt Highly concentrated insulin solutions and compositions
EP2254905B1 (en) 2008-03-14 2016-12-14 Novo Nordisk A/S Protease-stabilized insulin analogues
PT2254906T (pt) 2008-03-18 2017-01-03 Novo Nordisk As Análogos de insulina acilados, estabilizados contra proteases
CN103736082A (zh) 2008-10-17 2014-04-23 赛诺菲-安万特德国有限公司 胰岛素和glp-1激动剂的组合
CN102711804B (zh) 2009-11-13 2015-09-16 赛诺菲-安万特德国有限公司 包含glp-1激动剂和甲硫氨酸的药物组合物
AU2010317995B2 (en) 2009-11-13 2014-04-17 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist, an insulin, and methionine
CN101912600B (zh) * 2010-01-11 2014-01-29 杨国汉 改善胰岛素在溶液中稳定性的方法
US8637458B2 (en) * 2010-05-12 2014-01-28 Biodel Inc. Insulin with a stable basal release profile
AU2011202239C1 (en) 2010-05-19 2017-03-16 Sanofi Long-acting formulations of insulins
PT2611458T (pt) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
ES2550357T3 (es) 2011-08-29 2015-11-06 Sanofi-Aventis Deutschland Gmbh Combinación farmacéutica para su uso en el control glucémico en pacientes de diabetes de tipo 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
CN104364260B (zh) 2012-04-11 2017-02-22 诺和诺德股份有限公司 胰岛素制剂
US9381247B2 (en) * 2012-04-16 2016-07-05 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
US9399065B2 (en) 2012-04-16 2016-07-26 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and injection site pain of insulin
CN110354255B (zh) 2013-04-03 2024-05-14 赛诺菲 通过长效胰岛素制剂治疗糖尿病
MX366636B (es) 2013-10-07 2019-07-17 Novo Nordisk As Nuevo derivado de un análogo de insulina.
KR102578030B1 (ko) 2014-12-12 2023-09-14 사노피-아벤티스 도이칠란트 게엠베하 인슐린 글라진／릭시세나티드 고정비 제형
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
TWI700091B (zh) 2016-12-16 2020-08-01 丹麥商諾佛 儂迪克股份有限公司 含胰島素醫藥組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2076082A (en) * 1935-04-08 1937-04-06 Nordisk Insulinlab Therapeutic product and process
US2179384A (en) * 1937-04-05 1939-11-07 Univ Alberta Therapeutic composition and process of making it
US2190134A (en) * 1939-06-09 1940-02-13 Norton Co Grinding machine
US2538018A (en) * 1944-04-04 1951-01-16 Nordisk Insulinlab Crystalline product of insulin and alkaline protein and process of making it
US2474729A (en) * 1945-01-03 1949-06-28 Rhone Poulenc Sa Insulin preparations
US2801953A (en) * 1952-02-28 1957-08-06 Hoechst Ag Process of preparing crystallized insulin preparations
US3102077A (en) * 1953-08-19 1963-08-27 Christensen Henry Marinus Preparation of insulin containing 2.75 to 8 percent zinc content
DK98342C (da) * 1959-06-16 1964-03-31 Henry Marinus Dr Christensen Fremgangsmåde til fremstilling af et insulinpræparat til peroral applikation.
US3868358A (en) * 1971-04-30 1975-02-25 Lilly Co Eli Protamine-insulin product
GB1426061A (en) * 1972-12-28 1976-02-25 Ici Ltd Polypeptides
US3856771A (en) * 1973-07-16 1974-12-24 Lilly Co Eli Process for manufacturing alkali metal or ammonium insulin
US4196196A (en) * 1978-06-19 1980-04-01 Tiholiz Ivan C Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states
AU550068B2 (en) * 1981-03-10 1986-02-27 Novo Nordisk A/S Zinc insulin stabilized with calcium or magnesium salts
US4839341A (en) * 1984-05-29 1989-06-13 Eli Lilly And Company Stabilized insulin formulations
US4764592A (en) * 1987-04-23 1988-08-16 Eli Lilly And Company Crystalline human proinsulin and process for its production

Also Published As

Publication number Publication date
CA1316819C (en) 1993-04-27
PT85949A (en) 1987-11-01
PT85949B (pt) 1990-07-31
GR3004912T3 (enExample) 1993-04-28
FI874596L (fi) 1988-04-21
NO170754C (no) 1992-12-02
FI874596A0 (fi) 1987-10-19
DE3778287D1 (de) 1992-05-21
FI86254C (fi) 1992-08-10
HUT46232A (en) 1988-10-28
HU201475B (en) 1990-11-28
NO874347D0 (no) 1987-10-19
YU46665B (sh) 1994-01-20
PH23446A (en) 1989-08-07
EP0265213A2 (en) 1988-04-27
NO170754B (no) 1992-08-24
IE872799L (en) 1988-04-20
IE60264B1 (en) 1994-06-29
ES2033871T3 (es) 1993-04-01
FI86254B (fi) 1992-04-30
EP0265213B1 (en) 1992-04-15
AU7990787A (en) 1988-04-21
US5070186A (en) 1991-12-03
EP0265213A3 (en) 1988-11-09
KR880004819A (ko) 1988-06-27
CN87107049A (zh) 1988-07-06
YU191887A (en) 1989-04-30
AU616381B2 (en) 1991-10-31
NO874347L (no) 1988-04-21
NZ222214A (en) 1989-11-28

Similar Documents

Publication Publication Date Title
IL84203A (en) Insulin preparations and their production
SG50619A1 (en) Stabilized pharmaceutical composition and its production
EP0243132A3 (en) Artificial skin and its production
HU906229D0 (en) Medical preparations
GR862233B (en) Insulin analogues and process for their preparation
EP0293793A3 (en) Polypeptide and production thereof
PT84704A (en) Thiolactam-n-acetic derivatives their production and use
IL87529A0 (en) Water-hardening polymer preparations and their production
GR3003110T3 (en) Inosose derivatives and production thereof
ZA86936B (en) 11beta-phenyl-gonanes,their manufacture and pharmaceutical preparations containing them
JPS6413993A (en) Heteropolymer protein and its production
IL84418A0 (en) Elastomers and their preparation
GB2190918B (en) Polyanhydride-siloxanes and polyimide-siloxanes obtained therefrom
EP0194060A3 (en) Desmutagenic substances and their production
GB2181729B (en) Glucosylmoranoline derivatives and production thereof
DE3760806D1 (en) Monohalogenotrifluorooxetane and its preparation
ZA866196B (en) Novel quinaldinamide derivatives and their preparations
IL75244A0 (en) Nifedipine combination preparations and their production
EP0271829A3 (en) Delta-hydroxy-beta-lysine derivatives and their production
IL87779A0 (en) 4-azasaccharines,4-aza-dihydro-and-tetrahydro-saccharines and their preparation
EG18199A (en) Benzoylurea derivatives their production and their use
GB2194235B (en) Dichlorotrifluoromethyltoluenes and preparation thereof
EP0274066A3 (en) Benzothiazolones, and their production and use
AU7677087A (en) Dipropargyloxybenzene compounds and their production
JPS6422876A (en) 8 alpha-acylaminoergoline, manufacture and medicine

Legal Events

Date Code Title Description
RH Patent void