FI86254B - Foerfarande foer framstaellning av insulinpreparat. - Google Patents

Foerfarande foer framstaellning av insulinpreparat.

Info

Publication number
FI86254B
FI86254B FI874596A FI874596A FI86254B FI 86254 B FI86254 B FI 86254B FI 874596 A FI874596 A FI 874596A FI 874596 A FI874596 A FI 874596A FI 86254 B FI86254 B FI 86254B
Authority
FI
Finland
Prior art keywords
insulinpreparat
foerfarande foer
foer framstaellning
framstaellning
foerfarande
Prior art date
Application number
FI874596A
Other languages
English (en)
Other versions
FI874596A (fi
FI874596A0 (fi
FI86254C (fi
Inventor
Klavs Holger Joergensen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK503386A external-priority patent/DK503386D0/da
Priority claimed from DK356987A external-priority patent/DK356987D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI874596A0 publication Critical patent/FI874596A0/fi
Publication of FI874596A publication Critical patent/FI874596A/fi
Publication of FI86254B publication Critical patent/FI86254B/fi
Application granted granted Critical
Publication of FI86254C publication Critical patent/FI86254C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
FI874596A 1986-10-20 1987-10-19 Foerfarande foer framstaellning av insulinpreparat. FI86254C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK503386A DK503386D0 (da) 1986-10-20 1986-10-20 Peptidpraeparater
DK503386 1986-10-20
DK356987 1987-07-10
DK356987A DK356987D0 (fi) 1987-07-10 1987-07-10

Publications (4)

Publication Number Publication Date
FI874596A0 FI874596A0 (fi) 1987-10-19
FI874596A FI874596A (fi) 1988-04-21
FI86254B true FI86254B (fi) 1992-04-30
FI86254C FI86254C (fi) 1992-08-10

Family

ID=26067111

Family Applications (1)

Application Number Title Priority Date Filing Date
FI874596A FI86254C (fi) 1986-10-20 1987-10-19 Foerfarande foer framstaellning av insulinpreparat.

Country Status (18)

Country Link
US (1) US5070186A (fi)
EP (1) EP0265213B1 (fi)
KR (1) KR880004819A (fi)
CN (1) CN87107049A (fi)
AU (1) AU616381B2 (fi)
CA (1) CA1316819C (fi)
DE (1) DE3778287D1 (fi)
ES (1) ES2033871T3 (fi)
FI (1) FI86254C (fi)
GR (1) GR3004912T3 (fi)
HU (1) HU201475B (fi)
IE (1) IE60264B1 (fi)
IL (1) IL84203A (fi)
NO (1) NO170754C (fi)
NZ (1) NZ222214A (fi)
PH (1) PH23446A (fi)
PT (1) PT85949B (fi)
YU (1) YU46665B (fi)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5534488A (en) * 1993-08-13 1996-07-09 Eli Lilly And Company Insulin formulation
YU18596A (sh) * 1995-03-31 1998-07-10 Eli Lilly And Company Analogne formulacije monomernog insulina
JP2002500196A (ja) * 1998-01-09 2002-01-08 ノヴォ ノルディスク アクティーゼルスカブ 安定化させたインスリン組成物
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
DE10114178A1 (de) * 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
CN1278666C (zh) * 2001-08-27 2006-10-11 诺沃挪第克公司 一种药管及容纳这种药管的医药输送系统
MXPA05007182A (es) * 2002-12-31 2006-04-07 Altus Pharmaceuticals Inc Complejos de cristales de proteina y polimeros ionicos.
AU2003303646B2 (en) * 2002-12-31 2010-03-04 Altus Pharmaceuticals Inc. Human growth hormone crystals and methods for preparing them
CA2634053A1 (en) * 2005-12-23 2007-07-05 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them
JP5550338B2 (ja) 2006-07-31 2014-07-16 ノボ・ノルデイスク・エー／エス ペグ化持続型インスリン
CN101541830A (zh) 2006-09-22 2009-09-23 诺沃-诺迪斯克有限公司 蛋白酶抗性的胰岛素类似物
ES2563038T3 (es) 2007-04-30 2016-03-10 Novo Nordisk A/S Método para secar una composición proteica, una composición proteica seca y una composición farmacéutica que comprende la proteína seca
EP2152243A2 (en) * 2007-04-30 2010-02-17 Novo Nordisk A/S Highly concentrated insulin solutions and compositions
ES2618073T3 (es) 2008-03-14 2017-06-20 Novo Nordisk A/S Análogos de insulina estabilizados frente a proteasas
EP2910571B1 (en) 2008-03-18 2016-10-05 Novo Nordisk A/S Protease stabilized, acylated insulin analogues
DK2349324T3 (en) 2008-10-17 2017-12-11 Sanofi Aventis Deutschland COMBINATION OF AN INSULIN AND A GLP-1 AGONIST
JP5973918B2 (ja) 2009-11-13 2016-08-23 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト及びメチオニンを含む薬学的組成物
KR101836070B1 (ko) 2009-11-13 2018-03-09 사노피-아벤티스 도이칠란트 게엠베하 Ｇｌｐ－１ 작용제, 인슐린 및 메티오닌을 포함하는 약제학적 조성물
CN101912600B (zh) * 2010-01-11 2014-01-29 杨国汉 改善胰岛素在溶液中稳定性的方法
US8637458B2 (en) * 2010-05-12 2014-01-28 Biodel Inc. Insulin with a stable basal release profile
AU2011202239C1 (en) 2010-05-19 2017-03-16 Sanofi Long-acting formulations of insulins
PT2611458T (pt) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
CN108079281A (zh) 2011-08-29 2018-05-29 赛诺菲-安万特德国有限公司 用于2型糖尿病患者中的血糖控制的药物组合
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
CA2870313A1 (en) 2012-04-11 2013-10-17 Novo Nordisk A/S Insulin formulations
US9381247B2 (en) * 2012-04-16 2016-07-05 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
US9399065B2 (en) 2012-04-16 2016-07-26 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and injection site pain of insulin
EP3517122A1 (en) 2013-04-03 2019-07-31 Sanofi Treatment of diabetes mellitus by long-acting formulations of insulins
WO2015052088A1 (en) 2013-10-07 2015-04-16 Novo Nordisk A/S Novel derivative of an insulin analogue
CN107206058A (zh) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 甘精胰岛素/利西拉来固定比率配制剂
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
MX2019006463A (es) 2016-12-16 2019-08-14 Novo Nordisk As Composiciones farmaceuticas que contienen insulina.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2076082A (en) * 1935-04-08 1937-04-06 Nordisk Insulinlab Therapeutic product and process
US2179384A (en) * 1937-04-05 1939-11-07 Univ Alberta Therapeutic composition and process of making it
US2190134A (en) * 1939-06-09 1940-02-13 Norton Co Grinding machine
US2538018A (en) * 1944-04-04 1951-01-16 Nordisk Insulinlab Crystalline product of insulin and alkaline protein and process of making it
US2474729A (en) * 1945-01-03 1949-06-28 Rhone Poulenc Sa Insulin preparations
US2801953A (en) * 1952-02-28 1957-08-06 Hoechst Ag Process of preparing crystallized insulin preparations
US3102077A (en) * 1953-08-19 1963-08-27 Christensen Henry Marinus Preparation of insulin containing 2.75 to 8 percent zinc content
DK98342C (da) * 1959-06-16 1964-03-31 Henry Marinus Dr Christensen Fremgangsmåde til fremstilling af et insulinpræparat til peroral applikation.
US3868358A (en) * 1971-04-30 1975-02-25 Lilly Co Eli Protamine-insulin product
GB1426061A (en) * 1972-12-28 1976-02-25 Ici Ltd Polypeptides
US3856771A (en) * 1973-07-16 1974-12-24 Lilly Co Eli Process for manufacturing alkali metal or ammonium insulin
US4196196A (en) * 1978-06-19 1980-04-01 Tiholiz Ivan C Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states
AU550068B2 (en) * 1981-03-10 1986-02-27 Novo Nordisk A/S Zinc insulin stabilized with calcium or magnesium salts
US4839341A (en) * 1984-05-29 1989-06-13 Eli Lilly And Company Stabilized insulin formulations
US4764592A (en) * 1987-04-23 1988-08-16 Eli Lilly And Company Crystalline human proinsulin and process for its production

Also Published As

Publication number Publication date
EP0265213B1 (en) 1992-04-15
AU7990787A (en) 1988-04-21
CN87107049A (zh) 1988-07-06
PT85949A (en) 1987-11-01
FI874596A (fi) 1988-04-21
YU46665B (sh) 1994-01-20
NO170754B (no) 1992-08-24
US5070186A (en) 1991-12-03
DE3778287D1 (de) 1992-05-21
EP0265213A3 (en) 1988-11-09
IE872799L (en) 1988-04-20
HUT46232A (en) 1988-10-28
NZ222214A (en) 1989-11-28
NO874347D0 (no) 1987-10-19
GR3004912T3 (fi) 1993-04-28
IE60264B1 (en) 1994-06-29
NO874347L (no) 1988-04-21
PT85949B (pt) 1990-07-31
ES2033871T3 (es) 1993-04-01
CA1316819C (en) 1993-04-27
HU201475B (en) 1990-11-28
KR880004819A (ko) 1988-06-27
NO170754C (no) 1992-12-02
PH23446A (en) 1989-08-07
FI874596A0 (fi) 1987-10-19
AU616381B2 (en) 1991-10-31
EP0265213A2 (en) 1988-04-27
FI86254C (fi) 1992-08-10
YU191887A (en) 1989-04-30
IL84203A (en) 1993-04-04

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Owner name: NOVO NORDISK A/S