IL83047A - Monoclonal antibodies to pseudomonas aeruginosa flagella, method and cell line for their production and pharmaceutical compositions and kits containing them - Google Patents

Monoclonal antibodies to pseudomonas aeruginosa flagella, method and cell line for their production and pharmaceutical compositions and kits containing them

Info

Publication number
IL83047A
IL83047A IL83047A IL8304787A IL83047A IL 83047 A IL83047 A IL 83047A IL 83047 A IL83047 A IL 83047A IL 8304787 A IL8304787 A IL 8304787A IL 83047 A IL83047 A IL 83047A
Authority
IL
Israel
Prior art keywords
production
pharmaceutical compositions
cell line
monoclonal antibodies
pseudomonas aeruginosa
Prior art date
Application number
IL83047A
Other languages
English (en)
Other versions
IL83047A0 (en
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/946,554 external-priority patent/US4834976A/en
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of IL83047A0 publication Critical patent/IL83047A0/xx
Publication of IL83047A publication Critical patent/IL83047A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL83047A 1986-07-03 1987-07-01 Monoclonal antibodies to pseudomonas aeruginosa flagella, method and cell line for their production and pharmaceutical compositions and kits containing them IL83047A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88198486A 1986-07-03 1986-07-03
US06/946,554 US4834976A (en) 1986-07-03 1986-12-24 Monoclonal antibodies to pseudomonas aeruginosa flagella
US4814387A 1987-05-15 1987-05-15

Publications (2)

Publication Number Publication Date
IL83047A0 IL83047A0 (en) 1987-12-31
IL83047A true IL83047A (en) 1992-12-01

Family

ID=27367280

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83047A IL83047A (en) 1986-07-03 1987-07-01 Monoclonal antibodies to pseudomonas aeruginosa flagella, method and cell line for their production and pharmaceutical compositions and kits containing them

Country Status (19)

Country Link
JP (1) JP2639422B2 (ja)
KR (1) KR910002373B1 (ja)
AT (1) AT399885B (ja)
AU (1) AU615162B2 (ja)
BE (1) BE1000743A3 (ja)
CH (1) CH677796A5 (ja)
DE (1) DE3722098C2 (ja)
DK (1) DK172840B1 (ja)
ES (1) ES2013321A6 (ja)
FR (1) FR2601458B1 (ja)
GB (1) GB2192185B (ja)
IE (1) IE60888B1 (ja)
IL (1) IL83047A (ja)
IT (1) IT1221940B (ja)
LU (1) LU86938A1 (ja)
NL (1) NL194961C (ja)
OA (1) OA08629A (ja)
PT (1) PT85247B (ja)
SE (1) SE506421C2 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772464A (en) * 1985-08-01 1988-09-20 Miles Laboratories, Inc. Protective antibodies to serotypic determinants of flagellar antigens
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
GB2192185B (en) * 1986-07-03 1991-01-16 Genetic Systems Corp Monoclonal antibodies to pseudomonas aeruginosa flagella
CA1341375C (en) * 1988-10-12 2002-07-09 Baxter International Inc. Compositions and methods for the treatment and prevention of gram-negative bacterial infections
JPH02299594A (ja) * 1989-01-30 1990-12-11 Sumitomo Chem Co Ltd ヒトモノクローナル抗体およびその製法
WO1990013033A1 (en) * 1989-04-14 1990-11-01 Biocontrol Systems, Incorporated Process and device for detecting a particular motile organism
CA2073855C (en) * 1990-01-18 2007-04-24 Bill Elliot Cham Glycoalkaloids for controlling cellular autophagy
CA2751433A1 (en) * 2009-02-04 2010-08-12 Kalobios Pharmaceuticals, Inc. Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection
WO2011107989A1 (en) * 2010-03-01 2011-09-09 Lostam Biopharmaceuticals Ltd Improved therapeutic antibodies against flagellated pseudomonas aeruginosa

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8422649D0 (en) * 1984-09-07 1984-10-10 Technology Licence Co Ltd Monoclonal antibodies
JP2691708B2 (ja) * 1984-09-26 1997-12-17 住友製薬株式会社 ヒトモノクローナル抗体およびその製法
WO1986007382A1 (en) * 1985-06-06 1986-12-18 Genetic Systems Corporation Protective human monoclonal antibodies to pseudomonas aeruginosa exotoxin a
EP0211352B1 (en) * 1985-08-01 1994-03-16 Miles Inc. Protective antibodies to serotypic determinants of flagellar antigens
US4918163A (en) * 1985-09-27 1990-04-17 Pfizer Inc. Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
ZA868673B (en) * 1985-12-10 1988-07-27 Genetic Systems Corp Monoclonal antibodies cross-reactive and cross-protective against p.aeruginosa serotypes
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
GB2192185B (en) * 1986-07-03 1991-01-16 Genetic Systems Corp Monoclonal antibodies to pseudomonas aeruginosa flagella

Also Published As

Publication number Publication date
KR910002373B1 (ko) 1991-04-20
BE1000743A3 (fr) 1989-03-28
IT8721163A0 (it) 1987-07-02
LU86938A1 (fr) 1988-02-02
DK336687A (da) 1988-01-04
IE60888B1 (en) 1994-08-24
ES2013321A6 (es) 1990-05-01
IE871769L (en) 1988-01-03
FR2601458B1 (fr) 1992-08-21
GB8715347D0 (en) 1987-08-05
GB2192185A (en) 1988-01-06
IT1221940B (it) 1990-08-31
GB2192185B (en) 1991-01-16
IL83047A0 (en) 1987-12-31
SE506421C2 (sv) 1997-12-15
DK336687D0 (da) 1987-06-30
JPS63102697A (ja) 1988-05-07
SE8702734D0 (sv) 1987-07-02
CH677796A5 (ja) 1991-06-28
JP2639422B2 (ja) 1997-08-13
ATA168387A (de) 1994-12-15
KR880001815A (ko) 1988-04-27
NL194961C (nl) 2003-09-02
AU615162B2 (en) 1991-09-26
SE8702734L (sv) 1988-01-04
DE3722098C2 (de) 1998-06-04
AT399885B (de) 1995-08-25
PT85247A (en) 1987-08-01
OA08629A (en) 1988-11-30
DE3722098A1 (de) 1988-03-03
NL8701554A (nl) 1988-02-01
AU7495887A (en) 1988-01-07
PT85247B (pt) 1990-06-29
DK172840B1 (da) 1999-08-09
NL194961B (nl) 2003-05-01
FR2601458A1 (fr) 1988-01-15

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