IL82613A - 1-(hydroxystyryl)-5h-2,3-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

1-(hydroxystyryl)-5h-2,3-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL82613A
IL82613A IL82613A IL8261387A IL82613A IL 82613 A IL82613 A IL 82613A IL 82613 A IL82613 A IL 82613A IL 8261387 A IL8261387 A IL 8261387A IL 82613 A IL82613 A IL 82613A
Authority
IL
Israel
Prior art keywords
hydroxystyryl
preparation
pharmaceutical compositions
compositions containing
benzodiazepine derivatives
Prior art date
Application number
IL82613A
Other languages
English (en)
Other versions
IL82613A0 (en
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IL82613A0 publication Critical patent/IL82613A0/xx
Publication of IL82613A publication Critical patent/IL82613A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
IL82613A 1986-05-21 1987-05-21 1-(hydroxystyryl)-5h-2,3-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them IL82613A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU862140A HU195788B (en) 1986-05-21 1986-05-21 Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
IL82613A0 IL82613A0 (en) 1987-11-30
IL82613A true IL82613A (en) 1991-03-10

Family

ID=10957976

Family Applications (1)

Application Number Title Priority Date Filing Date
IL82613A IL82613A (en) 1986-05-21 1987-05-21 1-(hydroxystyryl)-5h-2,3-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (24)

Country Link
US (1) US4840948A (sv)
JP (1) JPS6322082A (sv)
AT (1) AT395009B (sv)
BE (1) BE1000573A4 (sv)
BG (1) BG46003A3 (sv)
CA (1) CA1280748C (sv)
CH (1) CH671226A5 (sv)
CS (1) CS262690B2 (sv)
DD (1) DD268943A5 (sv)
DE (1) DE3717080C2 (sv)
DK (1) DK258187A (sv)
ES (1) ES2005582A6 (sv)
FI (1) FI91964C (sv)
FR (1) FR2599034B1 (sv)
GB (1) GB2190677B (sv)
HU (1) HU195788B (sv)
IL (1) IL82613A (sv)
IT (1) IT1205665B (sv)
NL (1) NL8701213A (sv)
PL (1) PL147687B1 (sv)
PT (1) PT84923B (sv)
SE (1) SE468560B (sv)
SU (1) SU1503681A3 (sv)
YU (1) YU46675B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380721A (en) * 1990-09-10 1995-01-10 Sterling Winthrop Inc. Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents
ATE200487T1 (de) * 1995-02-09 2001-04-15 Egyt Gyogyszervegyeszeti Gyar 1-(hetero)arylvinyl-5h-2,3- benzodiazepinderivative verwendbar zur behandlung von erkrankungen des zentralnervensystems, sowie benzopyrylium intermediate zu ihrer herstellung
SK283859B6 (sk) * 1995-02-09 2004-03-02 EGIS Gyógyszergyár Rt. 1-[2'-(Substituovaný)vinyl]-5H-2,3-benzodiazepínové deriváty, spôsob ich prípravy a medziprodukty na ich prípravu, liečivá ich obsahujúce a ich použitie
HU224435B1 (hu) * 1995-02-09 2005-10-28 EGIS Gyógyszergyár Rt. Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények
ES2111493B1 (es) * 1996-02-08 1999-08-01 Egyt Gyogyszervegyeszeti Gyar Derivados de 1-(2- (vinilo substituido ) ) -5h-2,3-benzo-diazepina, procedimiento para su preparacion, composiciones farmaceuticas que los contienen y utilizaciones correspondientes.
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
US20040152695A1 (en) * 2002-12-03 2004-08-05 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine and uses thereof
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
CA2508542A1 (en) * 2002-12-03 2004-06-17 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5h-2,3-benzodiazepine and uses thereof
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
HUP0302449A3 (en) * 2003-08-04 2005-06-28 Egis Gyogyszergyar Nyilvanosan 8-chloro-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for producing them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK118660B (da) * 1966-12-09 1970-09-21 Egyt Gyogyszervegyeszeti Gyar Analogifremgangsmåde til fremstilling af 1-(3',4'-dimethoxyphenyl)-3-methyl-4-ethyl-6,7-dimethoxy-isoquinolin-N-imid.
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines

Also Published As

Publication number Publication date
GB2190677B (en) 1990-01-10
PL147687B1 (en) 1989-07-31
DE3717080A1 (de) 1987-11-26
FI91964B (sv) 1994-05-31
CS369087A2 (en) 1988-08-16
JPS6322082A (ja) 1988-01-29
HUT44521A (en) 1988-03-28
SE8702120D0 (sv) 1987-05-21
HU195788B (en) 1988-07-28
FI872255A (sv) 1987-11-22
CS262690B2 (en) 1989-03-14
FR2599034B1 (fr) 1989-06-09
IT8720619A0 (it) 1987-05-21
PT84923B (pt) 1990-02-08
BE1000573A4 (fr) 1989-02-07
PT84923A (en) 1987-06-01
FR2599034A1 (fr) 1987-11-27
YU90687A (en) 1988-08-31
DK258187A (da) 1987-11-22
US4840948A (en) 1989-06-20
CA1280748C (en) 1991-02-26
SE468560B (sv) 1993-02-08
CH671226A5 (sv) 1989-08-15
AT395009B (de) 1992-08-25
FI91964C (sv) 1994-09-12
DE3717080C2 (de) 1996-02-08
ES2005582A6 (es) 1989-03-16
YU46675B (sh) 1994-01-20
FI872255A0 (sv) 1987-05-21
IL82613A0 (en) 1987-11-30
BG46003A3 (en) 1989-09-15
IT1205665B (it) 1989-03-31
SU1503681A3 (ru) 1989-08-23
GB8712005D0 (en) 1987-06-24
GB2190677A (en) 1987-11-25
SE8702120L (sv) 1987-11-22
DD268943A5 (de) 1989-06-14
PL265812A1 (en) 1988-05-12
ATA130287A (de) 1992-01-15
DK258187D0 (da) 1987-05-21
NL8701213A (nl) 1987-12-16

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Legal Events

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