DK258187D0 - 1-(hydroxystyryl)-5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem - Google Patents

1-(hydroxystyryl)-5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem

Info

Publication number
DK258187D0
DK258187D0 DK258187A DK258187A DK258187D0 DK 258187 D0 DK258187 D0 DK 258187D0 DK 258187 A DK258187 A DK 258187A DK 258187 A DK258187 A DK 258187A DK 258187 D0 DK258187 D0 DK 258187D0
Authority
DK
Denmark
Prior art keywords
hydroxystyryl
procedures
preparing
pharmaceutical preparations
preparations containing
Prior art date
Application number
DK258187A
Other languages
English (en)
Other versions
DK258187A (da
Inventor
Tibor Lang
Jeno Koeroesi
Gyoergy Rabloczky
Tamas Hamori
Maria Kuhar
Istvan Polgari
Istvan Elekes
Gabor Zolyomi
Krisztina Heltai
Judit Sarossy
Zsuzsanna Lang
Imre Moravcsik
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of DK258187D0 publication Critical patent/DK258187D0/da
Publication of DK258187A publication Critical patent/DK258187A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK258187A 1986-05-21 1987-05-21 1-(hydroxystyryl)-5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem DK258187A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU862140A HU195788B (en) 1986-05-21 1986-05-21 Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DK258187D0 true DK258187D0 (da) 1987-05-21
DK258187A DK258187A (da) 1987-11-22

Family

ID=10957976

Family Applications (1)

Application Number Title Priority Date Filing Date
DK258187A DK258187A (da) 1986-05-21 1987-05-21 1-(hydroxystyryl)-5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem

Country Status (24)

Country Link
US (1) US4840948A (da)
JP (1) JPS6322082A (da)
AT (1) AT395009B (da)
BE (1) BE1000573A4 (da)
BG (1) BG46003A3 (da)
CA (1) CA1280748C (da)
CH (1) CH671226A5 (da)
CS (1) CS262690B2 (da)
DD (1) DD268943A5 (da)
DE (1) DE3717080C2 (da)
DK (1) DK258187A (da)
ES (1) ES2005582A6 (da)
FI (1) FI91964C (da)
FR (1) FR2599034B1 (da)
GB (1) GB2190677B (da)
HU (1) HU195788B (da)
IL (1) IL82613A (da)
IT (1) IT1205665B (da)
NL (1) NL8701213A (da)
PL (1) PL147687B1 (da)
PT (1) PT84923B (da)
SE (1) SE468560B (da)
SU (1) SU1503681A3 (da)
YU (1) YU46675B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380721A (en) * 1990-09-10 1995-01-10 Sterling Winthrop Inc. Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents
HU224435B1 (hu) * 1995-02-09 2005-10-28 EGIS Gyógyszergyár Rt. Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények
EP0726257B1 (en) * 1995-02-09 2001-04-11 Egis Gyogyszergyar Rt. 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepine derivatives useful for the treatment of central nervous system disorders, and benzopyrylium intermediates for their preparation
SK283859B6 (sk) * 1995-02-09 2004-03-02 EGIS Gyógyszergyár Rt. 1-[2'-(Substituovaný)vinyl]-5H-2,3-benzodiazepínové deriváty, spôsob ich prípravy a medziprodukty na ich prípravu, liečivá ich obsahujúce a ich použitie
ES2111493B1 (es) * 1996-02-08 1999-08-01 Egyt Gyogyszervegyeszeti Gyar Derivados de 1-(2- (vinilo substituido ) ) -5h-2,3-benzo-diazepina, procedimiento para su preparacion, composiciones farmaceuticas que los contienen y utilizaciones correspondientes.
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
WO2004069155A2 (en) * 2002-12-03 2004-08-19 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine and uses therof
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
MXPA05005895A (es) * 2002-12-03 2006-02-08 Vela Pharmaceuticals Inc Composicion farmaceutica de 1-(3, 4-dimetoxifenil)-4 -metil-5-etil -7-metoxi-8 -hidroxi- 5h-2, 3-benzodiacepina y usos de la misma.
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
HUP0302449A3 (en) * 2003-08-04 2005-06-28 Egis Gyogyszergyar Nyilvanosan 8-chloro-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for producing them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK118660B (da) * 1966-12-09 1970-09-21 Egyt Gyogyszervegyeszeti Gyar Analogifremgangsmåde til fremstilling af 1-(3',4'-dimethoxyphenyl)-3-methyl-4-ethyl-6,7-dimethoxy-isoquinolin-N-imid.
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines

Also Published As

Publication number Publication date
HU195788B (en) 1988-07-28
FI91964B (fi) 1994-05-31
FI872255A0 (fi) 1987-05-21
IL82613A0 (en) 1987-11-30
GB2190677A (en) 1987-11-25
CA1280748C (en) 1991-02-26
YU90687A (en) 1988-08-31
NL8701213A (nl) 1987-12-16
FI872255A (fi) 1987-11-22
FI91964C (fi) 1994-09-12
CS262690B2 (en) 1989-03-14
PT84923A (en) 1987-06-01
BG46003A3 (en) 1989-09-15
US4840948A (en) 1989-06-20
BE1000573A4 (fr) 1989-02-07
SE8702120L (sv) 1987-11-22
SE468560B (sv) 1993-02-08
CS369087A2 (en) 1988-08-16
ES2005582A6 (es) 1989-03-16
GB2190677B (en) 1990-01-10
DE3717080A1 (de) 1987-11-26
JPS6322082A (ja) 1988-01-29
SU1503681A3 (ru) 1989-08-23
GB8712005D0 (en) 1987-06-24
AT395009B (de) 1992-08-25
CH671226A5 (da) 1989-08-15
HUT44521A (en) 1988-03-28
FR2599034A1 (fr) 1987-11-27
IT1205665B (it) 1989-03-31
PL265812A1 (en) 1988-05-12
DD268943A5 (de) 1989-06-14
ATA130287A (de) 1992-01-15
FR2599034B1 (fr) 1989-06-09
PL147687B1 (en) 1989-07-31
YU46675B (sh) 1994-01-20
IL82613A (en) 1991-03-10
IT8720619A0 (it) 1987-05-21
DE3717080C2 (de) 1996-02-08
PT84923B (pt) 1990-02-08
SE8702120D0 (sv) 1987-05-21
DK258187A (da) 1987-11-22

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