IL78991A - Sustained release oral pharmaceutical composition with improved mucosal adhesion - Google Patents

Sustained release oral pharmaceutical composition with improved mucosal adhesion

Info

Publication number
IL78991A
IL78991A IL78991A IL7899186A IL78991A IL 78991 A IL78991 A IL 78991A IL 78991 A IL78991 A IL 78991A IL 7899186 A IL7899186 A IL 7899186A IL 78991 A IL78991 A IL 78991A
Authority
IL
Israel
Prior art keywords
cellulose
mucosa
sustained release
pharmaceutical composition
drug
Prior art date
Application number
IL78991A
Other languages
English (en)
Other versions
IL78991A0 (en
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of IL78991A0 publication Critical patent/IL78991A0/xx
Publication of IL78991A publication Critical patent/IL78991A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL78991A 1985-06-11 1986-06-02 Sustained release oral pharmaceutical composition with improved mucosal adhesion IL78991A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858514665A GB8514665D0 (en) 1985-06-11 1985-06-11 Oral pharmaceutical composition

Publications (2)

Publication Number Publication Date
IL78991A0 IL78991A0 (en) 1986-09-30
IL78991A true IL78991A (en) 1990-07-26

Family

ID=10580497

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78991A IL78991A (en) 1985-06-11 1986-06-02 Sustained release oral pharmaceutical composition with improved mucosal adhesion

Country Status (16)

Country Link
US (1) US4940587A (xx)
EP (1) EP0205282B1 (xx)
JP (1) JP2513999B2 (xx)
KR (1) KR890002949B1 (xx)
AT (1) ATE127687T1 (xx)
AU (1) AU595801B2 (xx)
CA (1) CA1277913C (xx)
DE (1) DE3650390T2 (xx)
DK (1) DK273086A (xx)
ES (1) ES8707110A1 (xx)
FI (1) FI88108C (xx)
GB (1) GB8514665D0 (xx)
IL (1) IL78991A (xx)
NO (1) NO172027C (xx)
PT (1) PT82746B (xx)
ZA (1) ZA864105B (xx)

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NL159577B (nl) * 1968-02-15 1979-03-15 Organon Nv Werkwijze ter bereiding van snel desintegrerende vaste vormstukken.
GB1405088A (en) * 1971-06-03 1975-09-03 Mundipharma Ag Slow release formulation
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4039653A (en) * 1974-01-23 1977-08-02 Defoney, Brenman, Mayes & Baron Long-acting articles for oral delivery and process
JPS5438167B2 (xx) * 1974-04-27 1979-11-19
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4259314A (en) * 1979-12-10 1981-03-31 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals
IE49324B1 (en) * 1979-12-19 1985-09-18 Euro Celtique Sa Controlled release compositions
JPS5758615A (en) * 1980-09-26 1982-04-08 Nippon Soda Co Ltd Film agnent and its preparation
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
CA1208558A (en) * 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
US4695591A (en) * 1985-03-29 1987-09-22 Schering Corporation Controlled release dosage forms comprising hydroxypropylmethylcellulose

Also Published As

Publication number Publication date
EP0205282A2 (en) 1986-12-17
FI88108C (fi) 1993-04-13
DK273086A (da) 1986-12-12
ES8707110A1 (es) 1987-07-16
FI88108B (fi) 1992-12-31
ES555899A0 (es) 1987-07-16
IL78991A0 (en) 1986-09-30
PT82746A (en) 1986-07-01
JP2513999B2 (ja) 1996-07-10
GB8514665D0 (en) 1985-07-10
NO862287L (no) 1986-12-12
DE3650390D1 (de) 1995-10-19
NO172027B (no) 1993-02-22
FI862479A0 (fi) 1986-06-10
EP0205282A3 (en) 1987-08-26
AU5828486A (en) 1986-12-18
KR870000068A (ko) 1987-02-16
FI862479A (fi) 1986-12-12
PT82746B (pt) 1988-04-21
NO172027C (no) 1993-06-02
DE3650390T2 (de) 1996-04-04
ATE127687T1 (de) 1995-09-15
US4940587A (en) 1990-07-10
JPS61286321A (ja) 1986-12-16
KR890002949B1 (ko) 1989-08-14
NO862287D0 (no) 1986-06-09
DK273086D0 (da) 1986-06-10
AU595801B2 (en) 1990-04-12
CA1277913C (en) 1990-12-18
EP0205282B1 (en) 1995-09-13
ZA864105B (en) 1987-01-28

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