ES8707110A1 - Un procedimiento para preparar una composicion farmaceutica oral, de accion prolongada, en forma de dosificacion unitaria solida. - Google Patents

Un procedimiento para preparar una composicion farmaceutica oral, de accion prolongada, en forma de dosificacion unitaria solida.

Info

Publication number
ES8707110A1
ES8707110A1 ES555899A ES555899A ES8707110A1 ES 8707110 A1 ES8707110 A1 ES 8707110A1 ES 555899 A ES555899 A ES 555899A ES 555899 A ES555899 A ES 555899A ES 8707110 A1 ES8707110 A1 ES 8707110A1
Authority
ES
Spain
Prior art keywords
mucosa
oral
pharmaceutical composition
dosage form
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555899A
Other languages
English (en)
Other versions
ES555899A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Publication of ES555899A0 publication Critical patent/ES555899A0/es
Publication of ES8707110A1 publication Critical patent/ES8707110A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA COMPOSICION FARMACEUTICA ORAL DE ACCION PROLONGADA, EN FORMA DE DOSIFICACION UNITARIA SOLIDA. COMPRENDE: A) FORMAR GRANULOS QUE CONTIENEN UN FARMACO, UN ALCOHOL ALIFATICO SUPERIOR EN UN 10 A 30% EN PESO DE LA FORMA DE DOSIFICACION, Y UNA HIDROXIALQUILCELULOSA HIDRATADA Y SOLUBLE EN AGUA EN UN 2 A 15% EN PESO DE LA FORMA DE DOSIFICACION; B) REVESTIR LOS GRANULOS CON UNA CELULOSA ADHESIVA A LA MUCOSA EN POLVO Y QUE COMPRENDE HIDROXIPROPILCELULOSA EN UN 2 AL 15% EN PESO DE LA FORMA DE DOSIFICACION; Y C) COMPRIMIR LOS GRANOS REVESTIDOS DE CELULOSA ADHESIVA A LA MUCOSA PARA PROPORCIONAR UNA FORMA DE DOSIFICACION UNITARIA SOLIDA. SE UTILIZA PARA FORMAR UNA COMPOSICION ORAL, ADAPTADA PARA APLICACION A LA MUCOSA DE LA CAVIDAD ORAL O NASAL.
ES555899A 1985-06-11 1986-06-10 Un procedimiento para preparar una composicion farmaceutica oral, de accion prolongada, en forma de dosificacion unitaria solida. Expired ES8707110A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858514665A GB8514665D0 (en) 1985-06-11 1985-06-11 Oral pharmaceutical composition

Publications (2)

Publication Number Publication Date
ES555899A0 ES555899A0 (es) 1987-07-16
ES8707110A1 true ES8707110A1 (es) 1987-07-16

Family

ID=10580497

Family Applications (1)

Application Number Title Priority Date Filing Date
ES555899A Expired ES8707110A1 (es) 1985-06-11 1986-06-10 Un procedimiento para preparar una composicion farmaceutica oral, de accion prolongada, en forma de dosificacion unitaria solida.

Country Status (16)

Country Link
US (1) US4940587A (es)
EP (1) EP0205282B1 (es)
JP (1) JP2513999B2 (es)
KR (1) KR890002949B1 (es)
AT (1) ATE127687T1 (es)
AU (1) AU595801B2 (es)
CA (1) CA1277913C (es)
DE (1) DE3650390T2 (es)
DK (1) DK273086A (es)
ES (1) ES8707110A1 (es)
FI (1) FI88108C (es)
GB (1) GB8514665D0 (es)
IL (1) IL78991A (es)
NO (1) NO172027C (es)
PT (1) PT82746B (es)
ZA (1) ZA864105B (es)

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ZA864105B (en) 1987-01-28
DK273086D0 (da) 1986-06-10
JP2513999B2 (ja) 1996-07-10
PT82746A (en) 1986-07-01
FI88108C (fi) 1993-04-13
ATE127687T1 (de) 1995-09-15
KR870000068A (ko) 1987-02-16
NO862287L (no) 1986-12-12
ES555899A0 (es) 1987-07-16
DE3650390D1 (de) 1995-10-19
IL78991A (en) 1990-07-26
AU5828486A (en) 1986-12-18
CA1277913C (en) 1990-12-18
NO172027B (no) 1993-02-22
NO172027C (no) 1993-06-02
JPS61286321A (ja) 1986-12-16
GB8514665D0 (en) 1985-07-10
IL78991A0 (en) 1986-09-30
DE3650390T2 (de) 1996-04-04
FI862479A0 (fi) 1986-06-10
US4940587A (en) 1990-07-10
AU595801B2 (en) 1990-04-12
DK273086A (da) 1986-12-12
KR890002949B1 (ko) 1989-08-14
EP0205282A3 (en) 1987-08-26
EP0205282A2 (en) 1986-12-17
NO862287D0 (no) 1986-06-09
FI862479A (fi) 1986-12-12
FI88108B (fi) 1992-12-31
EP0205282B1 (en) 1995-09-13
PT82746B (pt) 1988-04-21

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