IL78954A - Hydantoin spirocondensed with benzopyran and quinoline derivatives and pharmaceutical compositions containing them - Google Patents

Hydantoin spirocondensed with benzopyran and quinoline derivatives and pharmaceutical compositions containing them

Info

Publication number
IL78954A
IL78954A IL78954A IL7895486A IL78954A IL 78954 A IL78954 A IL 78954A IL 78954 A IL78954 A IL 78954A IL 7895486 A IL7895486 A IL 7895486A IL 78954 A IL78954 A IL 78954A
Authority
IL
Israel
Prior art keywords
spirocondensed
benzopyran
hydantoin
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL78954A
Other languages
English (en)
Other versions
IL78954A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL78954A0 publication Critical patent/IL78954A0/xx
Publication of IL78954A publication Critical patent/IL78954A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL78954A 1985-05-29 1986-05-28 Hydantoin spirocondensed with benzopyran and quinoline derivatives and pharmaceutical compositions containing them IL78954A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/738,924 US4575507A (en) 1985-05-29 1985-05-29 Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use

Publications (2)

Publication Number Publication Date
IL78954A0 IL78954A0 (en) 1986-09-30
IL78954A true IL78954A (en) 1989-09-28

Family

ID=24970055

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78954A IL78954A (en) 1985-05-29 1986-05-28 Hydantoin spirocondensed with benzopyran and quinoline derivatives and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4575507A (de)
EP (1) EP0203791B1 (de)
JP (1) JPS61277671A (de)
KR (1) KR890001548B1 (de)
AT (1) ATE46332T1 (de)
AU (1) AU560429B2 (de)
DD (5) DD251972A5 (de)
DE (1) DE3665584D1 (de)
DK (1) DK248886A (de)
EG (1) EG17859A (de)
ES (2) ES8800228A1 (de)
FI (1) FI862251A7 (de)
GR (1) GR861388B (de)
HU (4) HUT49879A (de)
IL (1) IL78954A (de)
NO (1) NO862123L (de)
NZ (1) NZ216334A (de)
PH (1) PH22213A (de)
PL (5) PL146020B1 (de)
PT (1) PT82650B (de)
ZA (1) ZA863934B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000807A1 (en) * 1984-07-20 1986-02-13 Pfizer Inc. Spiro-imidazolones for treatment of diabetes complications
US4762839A (en) * 1985-06-06 1988-08-09 Tanabe Seiyaku Co., Ltd. Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications
JPS63132889A (ja) * 1986-11-21 1988-06-04 Tanabe Seiyaku Co Ltd キナゾリノン誘導体
WO1988006887A1 (en) * 1987-03-20 1988-09-22 Alcon Laboratories, Inc. Use of aldose reductase inhibitors to enhance insulin sensitivity in diabetes mellitus
US5202339A (en) * 1987-08-28 1993-04-13 Mochida Pharmaceutical Co., Ltd. Hydantoin derivatives
US5004751A (en) * 1987-08-28 1991-04-02 Mochida Pharmaceutical Co., Ltd. Hydantoin derivatives
FI902028A7 (fi) * 1988-08-24 1990-04-23 Mochida Pharm Co Ltd Hydantoiinijohdannaisia
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
US8326636B2 (en) * 2008-01-16 2012-12-04 Canyon Ip Holdings Llc Using a physical phenomenon detector to control operation of a speech recognition engine
WO2013117568A1 (de) * 2012-02-09 2013-08-15 Boehringer Ingelheim International Gmbh Verfahren zur stereoselektiven synthese von 1,4-geschützten 9-hydroxy-5-oxo-1,4-diaza-spiro [5.5] undecane

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117230A (en) 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents
US4235911A (en) * 1979-06-13 1980-11-25 Pfizer Inc. Hydantoin derivatives
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
DE3367103D1 (en) * 1982-11-10 1986-11-27 Pfizer Sorbinil by optical resolution with aminopinane derivatives
US4556670A (en) 1982-12-06 1985-12-03 Pfizer Inc. Spiro-3-hetero-azolones for treatment of diabetic complications
SU1380610A3 (ru) * 1982-12-06 1988-03-07 Пфайзер Инк. (Фирма) Способ получени спирогетероазолидиндионов или их фармацевтически приемлемых солей
DE3561198D1 (en) * 1984-03-23 1988-01-28 Pfizer Spiro-indenes and spiro-1,2-dihydro-naphthalenes for treatment of diabetic complications
US4762838A (en) 1985-08-30 1988-08-09 Pfizer Inc. Quinazolin-4(3H)-one derivatives as anticoccidial agents

Also Published As

Publication number Publication date
PL147400B1 (en) 1989-05-31
AU560429B2 (en) 1987-04-09
DK248886D0 (da) 1986-05-28
HUT49879A (en) 1989-11-28
NZ216334A (en) 1988-08-30
EP0203791A1 (de) 1986-12-03
DD273258A5 (de) 1989-11-08
ES8800228A1 (es) 1987-11-01
PH22213A (en) 1988-06-28
ATE46332T1 (de) 1989-09-15
JPS61277671A (ja) 1986-12-08
ES555375A0 (es) 1987-11-01
ES557391A0 (es) 1988-02-16
KR860008984A (ko) 1986-12-19
PT82650A (en) 1986-06-01
ES8801830A1 (es) 1988-02-16
HUT44767A (en) 1988-04-28
HU199845B (en) 1990-03-28
FI862251L (fi) 1986-11-30
AU5801286A (en) 1987-01-08
DD264213A5 (de) 1989-01-25
PL266365A1 (en) 1988-03-03
EP0203791B1 (de) 1989-09-13
PT82650B (pt) 1988-11-30
ZA863934B (en) 1988-01-27
DD264214A5 (de) 1989-01-25
HU196060B (en) 1988-09-28
PL147399B1 (en) 1989-05-31
FI862251A7 (fi) 1986-11-30
FI862251A0 (fi) 1986-05-28
PL147397B1 (en) 1989-05-31
EG17859A (en) 1991-11-30
KR890001548B1 (en) 1989-05-08
DE3665584D1 (de) 1989-10-19
IL78954A0 (en) 1986-09-30
US4575507A (en) 1986-03-11
GR861388B (en) 1986-09-17
DD251972A5 (de) 1987-12-02
DK248886A (da) 1986-11-30
PL266364A1 (en) 1988-03-03
NO862123L (no) 1986-12-01
PL146020B1 (en) 1988-12-31
PL147398B1 (en) 1989-05-31
PL266363A1 (en) 1988-03-03
DD264215A5 (de) 1989-01-25
HUT49882A (en) 1989-11-28
PL266366A1 (en) 1988-03-03
HU893127D0 (en) 1990-01-28

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