FI861410A0 - Foerfarande foer framstaellning av terapeutiskt aktiva aminopropanolderivat. - Google Patents

Foerfarande foer framstaellning av terapeutiskt aktiva aminopropanolderivat.

Info

Publication number
FI861410A0
FI861410A0 FI861410A FI861410A FI861410A0 FI 861410 A0 FI861410 A0 FI 861410A0 FI 861410 A FI861410 A FI 861410A FI 861410 A FI861410 A FI 861410A FI 861410 A0 FI861410 A0 FI 861410A0
Authority
FI
Finland
Prior art keywords
carbon atoms
group
straight
replaced
chained
Prior art date
Application number
FI861410A
Other languages
English (en)
Other versions
FI861410A (fi
Inventor
Herbert Simon
Helmut Michel
Wolfgang Bartsch
Klaus Strein
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI861410A0 publication Critical patent/FI861410A0/fi
Publication of FI861410A publication Critical patent/FI861410A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measurement Of Force In General (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Indole Compounds (AREA)
FI861410A 1985-04-06 1986-04-01 Foerfarande foer framstaellning av terapeutiskt aktiva aminopropanolderivat. FI861410A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853512627 DE3512627A1 (de) 1985-04-06 1985-04-06 Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
FI861410A0 true FI861410A0 (fi) 1986-04-01
FI861410A FI861410A (fi) 1986-10-07

Family

ID=6267498

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861410A FI861410A (fi) 1985-04-06 1986-04-01 Foerfarande foer framstaellning av terapeutiskt aktiva aminopropanolderivat.

Country Status (15)

Country Link
US (1) US4863949A (fi)
EP (1) EP0200915B1 (fi)
JP (1) JPS61236758A (fi)
AT (1) ATE46688T1 (fi)
AU (1) AU5552886A (fi)
CS (1) CS223886A2 (fi)
DD (1) DD247214A5 (fi)
DE (2) DE3512627A1 (fi)
DK (1) DK155186A (fi)
ES (1) ES8705371A1 (fi)
FI (1) FI861410A (fi)
GR (1) GR860900B (fi)
HU (1) HU198444B (fi)
IL (1) IL78352A0 (fi)
ZA (1) ZA862407B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3705622A1 (de) * 1987-02-21 1988-09-01 Boehringer Mannheim Gmbh Neue amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
US5229412A (en) * 1988-03-25 1993-07-20 The Board Of Trustees Of The Leland Stanford Junior University Method for relieving anxiety using 5-hydroxytryptamine-1a-receptor-binding compounds
US5428061A (en) * 1988-09-15 1995-06-27 Schwarz Pharma Ag Organic nitrates and method for their preparation
JP2628756B2 (ja) * 1988-09-15 1997-07-09 シュバルツファルマ アクチェンゲゼルシャフト 新規有機ニトレート及びそれらの製造方法
NL8802276A (nl) * 1988-09-15 1990-04-02 Cedona Pharm Bv Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat.
DE3836021A1 (de) * 1988-10-22 1990-05-03 Boehringer Mannheim Gmbh Arzneimittel enthaltend nitroxyalkylamine mit amidfunktion und verfahren zur herstellung dieser verbindungen
US5284872A (en) * 1989-09-12 1994-02-08 Schwarz Pharma Ag Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof
DE4011505C2 (de) * 1990-04-10 1995-01-12 Sanol Arznei Schwarz Gmbh Nitratoalkancarbonsäure-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US5925658A (en) * 1995-03-02 1999-07-20 Sankyo Company, Limited Optically active thiazolidinone derivative
DE19616020A1 (de) * 1996-04-23 1997-10-30 Huels Chemische Werke Ag Neue Polyamine sowie ein Verfahren zu ihrer Herstellung
US5807847A (en) * 1996-06-04 1998-09-15 Queen's University At Kingston Nitrate esters
US6310052B1 (en) 1996-06-04 2001-10-30 Queen's University At Kingston Nitrate esters and their use for neurological conditions
US20050137191A1 (en) * 1996-06-04 2005-06-23 Thatcher Gregory R. Nitrate esters and their use for mitigating cellular damage
AU2004266705A1 (en) * 2003-08-20 2005-03-03 Nitromed, Inc. Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
PL380065A1 (pl) * 2003-12-02 2006-12-11 Nicox S.A. Nitrooksypochodne karwedilolu i inne beta blokery jako leki przeciwko nadciśnieniu
AU2005304770A1 (en) * 2004-11-08 2006-05-18 Nicox S.A. Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders
CN115010631A (zh) * 2021-03-05 2022-09-06 中国石油化工股份有限公司 一种从天然气中脱除硫化氢及硫醇的化合物及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH512427A (de) * 1967-12-18 1971-09-15 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec. -alkylaminopropanen
SE379196B (fi) * 1971-06-24 1975-09-29 Sandoz Ag
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
ZA742728B (en) * 1973-05-08 1975-04-30 Simes Pharmaceutical composition for the treatment of coronaric ailments
GB1508208A (en) * 1975-12-05 1978-04-19 Ici Ltd Amide derivatives
GB1540463A (en) * 1976-10-07 1979-02-14 Ici Ltd Alkanolamine derivatives
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung
CH636856A5 (en) * 1978-07-17 1983-06-30 Sandoz Ag 4-(3-Aminopropoxy)indole derivatives, their preparation and medicines containing them
GB2044251B (en) * 1978-12-01 1983-03-23 Bristol Myers Co Phenoxypropanolamine derivatives
JPS5677257A (en) * 1979-11-29 1981-06-25 Teikoku Chem Ind Corp Ltd Drug having beta-blocking activity
JPS56113748A (en) * 1980-02-13 1981-09-07 Kowa Co Aminoethanol derivative and its preparation
DE3426419A1 (de) * 1984-07-18 1986-01-23 Boehringer Mannheim Gmbh, 6800 Mannheim Neue oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte

Also Published As

Publication number Publication date
CS223886A2 (en) 1989-02-10
HU198444B (en) 1989-10-30
DK155186A (da) 1986-10-07
DE3665862D1 (en) 1989-11-02
EP0200915A1 (de) 1986-11-12
JPS61236758A (ja) 1986-10-22
DD247214A5 (de) 1987-07-01
ATE46688T1 (de) 1989-10-15
DE3512627A1 (de) 1986-10-09
ZA862407B (en) 1986-11-26
IL78352A0 (en) 1986-07-31
FI861410A (fi) 1986-10-07
AU5552886A (en) 1986-10-09
ES8705371A1 (es) 1987-05-16
EP0200915B1 (de) 1989-09-27
GR860900B (en) 1986-08-04
US4863949A (en) 1989-09-05
ES553684A0 (es) 1987-05-16
HUT40617A (en) 1987-01-28
DK155186D0 (da) 1986-04-04

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Owner name: BOEHRINGER MANNHEIM GMBH