CH512427A - Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec. -alkylaminopropanen - Google Patents

Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec. -alkylaminopropanen

Info

Publication number
CH512427A
CH512427A CH1874168A CH1874168A CH512427A CH 512427 A CH512427 A CH 512427A CH 1874168 A CH1874168 A CH 1874168A CH 1874168 A CH1874168 A CH 1874168A CH 512427 A CH512427 A CH 512427A
Authority
CH
Switzerland
Prior art keywords
alkylaminopropanes
phenoxy
sec
hydroxy
preparation
Prior art date
Application number
CH1874168A
Other languages
English (en)
Inventor
Herbert Dr Koeppe
Werner Dr Kummer
Helmut Dr Staehle
Karl Dr Zeile
Werner Dr Traunecker
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to CH1128871A priority Critical patent/CH559718A5/xx
Priority to CH333771A priority patent/CH513812A/de
Priority to CH1128771A priority patent/CH583174A5/xx
Priority to CH333471A priority patent/CH513115A/de
Priority to CH333671A priority patent/CH513117A/de
Priority to CH334171A priority patent/CH513813A/de
Priority to CH33971A priority patent/CH513118A/de
Priority to CH333871A priority patent/CH553745A/de
Priority to CH334071A priority patent/CH526511A/de
Priority to CH333571A priority patent/CH513116A/de
Publication of CH512427A publication Critical patent/CH512427A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CH1874168A 1967-12-18 1968-12-17 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec. -alkylaminopropanen CH512427A (de)

Priority Applications (10)

Application Number Priority Date Filing Date Title
CH1128871A CH559718A5 (de) 1967-12-18 1968-12-17
CH333771A CH513812A (de) 1967-12-18 1968-12-17 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec.-alkylaminopropanen
CH1128771A CH583174A5 (de) 1967-12-18 1968-12-17
CH333471A CH513115A (de) 1967-12-18 1968-12-17 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec. -alkylaminopropanen
CH333671A CH513117A (de) 1967-12-18 1968-12-17 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec.alkylaminopropanen
CH334171A CH513813A (de) 1967-12-18 1968-12-17 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec.-alkylaminopropanen
CH33971A CH513118A (de) 1967-12-18 1968-12-17 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec.alkylaminopropanen
CH333871A CH553745A (de) 1967-12-18 1968-12-17 Verfahren zur herstellung von neuen racemischen oder optisch aktiven 1-phenoxy-2-hydroxy-3-sec.alkylaminopropanen.
CH334071A CH526511A (de) 1967-12-18 1968-12-17 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec.-alkylaminopropanen
CH333571A CH513116A (de) 1967-12-18 1968-12-17 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec. -alkylaminopropanen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEB0095902 1967-12-18
DEB0095988 1967-12-22

Publications (1)

Publication Number Publication Date
CH512427A true CH512427A (de) 1971-09-15

Family

ID=25968397

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1874168A CH512427A (de) 1967-12-18 1968-12-17 Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-sec. -alkylaminopropanen

Country Status (11)

Country Link
US (1) US3644469A (de)
JP (1) JPS5210854B1 (de)
BE (1) BE725679A (de)
CA (1) CA956641A (de)
CH (1) CH512427A (de)
DK (1) DK129447B (de)
ES (8) ES361530A1 (de)
FR (2) FR1595323A (de)
GB (1) GB1260848A (de)
NL (1) NL163775C (de)
SE (1) SE358382B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975539A (en) * 1935-11-15 1976-08-17 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing an N,N-bis-(3-phenoxy-2-hydroxy-propyl)-alkylenediamine and method of use
SE384853B (sv) * 1972-04-04 1976-05-24 Haessle Ab Forfarande for framstellning av nya aminer
FR2119843B1 (de) * 1970-12-28 1974-03-22 Laroche Navarro Labo
US4145442A (en) * 1972-04-04 1979-03-20 Aktiebolaget Hassle Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases
JPS49245A (de) * 1972-04-17 1974-01-05
ZA741812B (en) * 1973-04-18 1975-04-30 Haessle A New amines and process for their preparation
US4191765A (en) * 1976-05-25 1980-03-04 Hoechst Aktiengesellschaft 1-Aryloxy-2-hydroxy-3-aminopropanes
DE2645710C2 (de) * 1976-10-09 1985-06-27 Merck Patent Gmbh, 6100 Darmstadt Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung
US4328213A (en) * 1979-11-28 1982-05-04 Schering Corporation Stable injectable labetalol formulation
US4347177A (en) * 1980-04-14 1982-08-31 Burroughs Wellcome Co. Compounds and methods of making them
SE8004088L (sv) * 1980-06-02 1981-12-03 Haessle Ab Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ...
SE8004087L (sv) * 1980-06-02 1981-12-03 Haessle Ab Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ...
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
JPS60100961U (ja) * 1983-12-15 1985-07-10 豊根　實 植木鉢
DE3512627A1 (de) * 1985-04-06 1986-10-09 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel
US4665094A (en) * 1985-08-29 1987-05-12 Merck & Co., Inc. Oculoselective beta-blockers for treatment of elevated intraocular pressure
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US5480908A (en) * 1993-12-13 1996-01-02 American Cyanamid Company β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions
AU1890201A (en) * 1999-12-14 2001-06-25 Showa Denko Kabushiki Kaisha Process for producing salt of cyanobenzylamine or derivative

Also Published As

Publication number Publication date
ES379738A1 (es) 1973-02-01
ES379739A1 (es) 1973-02-01
ES379736A1 (es) 1973-02-01
GB1260848A (en) 1972-01-19
FR1595323A (de) 1970-06-08
DK129447B (da) 1974-10-14
ES361530A1 (es) 1970-11-01
JPS5210854B1 (de) 1977-03-26
NL163775B (nl) 1980-05-16
DK129447C (de) 1975-03-03
BE725679A (de) 1969-06-18
ES379735A1 (es) 1973-01-16
NL163775C (nl) 1980-10-15
FR8262M (de) 1970-10-19
SE358382B (de) 1973-07-30
US3644469A (en) 1972-02-22
ES379737A1 (es) 1973-02-01
ES379731A1 (es) 1973-01-16
NL6818101A (de) 1969-06-20
ES379733A1 (es) 1973-01-16
CA956641A (en) 1974-10-22

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