IL78373A - Process for purifying proinsulin-like materials - Google Patents

Process for purifying proinsulin-like materials

Info

Publication number
IL78373A
IL78373A IL78373A IL7837386A IL78373A IL 78373 A IL78373 A IL 78373A IL 78373 A IL78373 A IL 78373A IL 7837386 A IL7837386 A IL 7837386A IL 78373 A IL78373 A IL 78373A
Authority
IL
Israel
Prior art keywords
proinsulin
purifying
materials
acetone
support
Prior art date
Application number
IL78373A
Other languages
English (en)
Other versions
IL78373A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL78373A0 publication Critical patent/IL78373A0/xx
Publication of IL78373A publication Critical patent/IL78373A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL78373A 1985-04-08 1986-03-31 Process for purifying proinsulin-like materials IL78373A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/720,641 US4616078A (en) 1985-04-08 1985-04-08 Process for purifying proinsulin-like materials

Publications (2)

Publication Number Publication Date
IL78373A0 IL78373A0 (en) 1986-07-31
IL78373A true IL78373A (en) 1990-07-12

Family

ID=24894751

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78373A IL78373A (en) 1985-04-08 1986-03-31 Process for purifying proinsulin-like materials

Country Status (12)

Country Link
US (1) US4616078A (de)
EP (1) EP0197764B1 (de)
JP (1) JPH0796559B2 (de)
KR (1) KR890001243B1 (de)
AT (1) ATE91690T1 (de)
AU (1) AU593242B2 (de)
CA (1) CA1284249C (de)
DE (1) DE3688712T2 (de)
DK (1) DK173414B1 (de)
HU (1) HU205138B (de)
IE (1) IE60570B1 (de)
IL (1) IL78373A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3738541A1 (de) * 1987-11-13 1989-05-24 Hoechst Ag Verfahren zur isolierung und reinigung von hirudin
US4764592A (en) * 1987-04-23 1988-08-16 Eli Lilly And Company Crystalline human proinsulin and process for its production
DK340189D0 (da) * 1989-07-10 1989-07-10 Jens Villadsens Fabrikker A S Fremgangsmaade til fremstilling af en fuldklaebet belaegning paa et underlag
US5071560A (en) * 1989-07-17 1991-12-10 Uop Process for purifying phenylalanine
US6001604A (en) * 1993-12-29 1999-12-14 Bio-Technology General Corp. Refolding of proinsulins without addition of reducing agents
DE4405179A1 (de) * 1994-02-18 1995-08-24 Hoechst Ag Verfahren zur Gewinnung von Insulin mit korrekt verbundenen Cystinbrücken
US7741536B2 (en) 1997-08-07 2010-06-22 University Of Central Florida Research Foundation, Inc. Expression of human serum albumin in plastids
US20030204864A1 (en) * 2001-02-28 2003-10-30 Henry Daniell Pharmaceutical proteins, human therapeutics, human serum albumin, insulin, native cholera toxic b submitted on transgenic plastids
KR100253916B1 (ko) * 1997-12-29 2000-05-01 김충환 사람 인슐린 전구체의 제조방법
DK1071955T4 (da) * 1998-04-17 2009-06-15 Innogenetics Nv Forbedrede immundiagnostiske assays, som anvender reduktionsmidler
US20100251425A9 (en) 1998-05-15 2010-09-30 University Of Central Florida Expression of human interferon in transgenic chloroplasts
DE19838097A1 (de) * 1998-08-24 2000-03-02 Hoechst Marion Roussel De Gmbh Verfahren zur chromatographischen Reinigung von Insulinen
CA2402066C (en) * 2000-03-01 2015-09-29 Auburn University Plastid transformation vectors for expressing human proteins in plants

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3649456A (en) * 1969-09-08 1972-03-14 Rohm & Haas Separation of polypeptide substances with macroreticular resins
US3907676A (en) * 1970-07-28 1975-09-23 Novo Terapeutisk Labor As Process for purifying insulin
US3876623A (en) * 1973-05-09 1975-04-08 Lilly Co Eli Process for purifying insulin
AU5397579A (en) * 1978-12-26 1980-07-03 Eli Lilly And Company Purifying insulin
US4430266A (en) * 1980-11-28 1984-02-07 Eli Lilly And Company Process for producing an insulin precursor

Also Published As

Publication number Publication date
JPH0796559B2 (ja) 1995-10-18
AU593242B2 (en) 1990-02-08
HU205138B (en) 1992-03-30
KR890001243B1 (ko) 1989-04-28
JPS61236796A (ja) 1986-10-22
DE3688712T2 (de) 1993-11-25
KR860008277A (ko) 1986-11-14
IE860887L (en) 1986-10-08
EP0197764A3 (en) 1988-08-31
CA1284249C (en) 1991-05-14
DK150586D0 (da) 1986-04-03
EP0197764B1 (de) 1993-07-21
IL78373A0 (en) 1986-07-31
EP0197764A2 (de) 1986-10-15
ATE91690T1 (de) 1993-08-15
AU5565586A (en) 1986-10-16
DK173414B1 (da) 2000-10-02
US4616078A (en) 1986-10-07
DE3688712D1 (de) 1993-08-26
DK150586A (da) 1986-10-09
IE60570B1 (en) 1994-07-27
HUT40680A (en) 1987-01-28

Similar Documents

Publication Publication Date Title
IE860887L (en) Purifying proinsulin-like materials
EP0282317A3 (de) Gereinigter Wachstumsfaktor, abstammend von Blutplättchen, und Verfahren zu dessen Reinigung
DE3064133D1 (en) Purification of human growth hormone
IL78374A0 (en) Improvements in or relating to a process for purifying growth hormone-like materials
JPS5223017A (en) Process for purification of (meth) acrylic acid or its esters
FR2575669B1 (fr) Procede pour la separation des isotopes d'uranium par chromatographie d'oxydoreduction
FR2557872B1 (fr) Procede d'isolement de l-amino-acides d'un melange reactionnel
HU895637D0 (en) Process for adsorptive separation of para-xylene employing tetraline desorbent
DE3664039D1 (en) Process for the preparation of unsaturated compounds by elimination reaction
ES8607343A1 (es) Procedimiento para la separacion de mezclas a base de insulina, derivados de insulina y, eventualmente, impurezas.
AU568694B2 (en) N-benzyl-n-phenyl-b-pyrrolidinyl-f-isobutoxy-propylamine
ES2004796A6 (es) Un procedimiento continuo para separar acidos a partir de una mezcla de acidos y sales de acidos correspondientes
IL125414A (en) PROCESS FOR THE PURIFICATION OF 11beta-21-DIHYDROXY-2'-METHYL-5'betaH-PREGNA-1,4-DIENO [17,16-D] OXAZOLINE-3,20-DIONE
SE8204756D0 (sv) Forfarande for rening av riboflavin-5Ÿ-monofosfat
YU155789A (en) Process for adsorptive separation of para-xylene by using diethyltoluole
EP0463988A3 (en) Process for concentrating or separating mixtures of organic compounds
GB2321859B (en) Reversed phase chromatographic process
JPS54144389A (en) Purification of 7-aminocephem compound
JPS5791739A (en) Purification and separation of vitamin b12 and adsorbing agent thereof
OA08918A (fr) Procédé d'enrichissement de la canallite par flottation.
KR890014455A (ko) 11a-클로로-5-히드록시-6-메틸렌 테트라사이클린의 분리 정제방법
CS134184A1 (en) Method of organic substances' mixture adsorbing separation

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
KB Patent renewed